Rchr
J-GLOBAL ID：201701007127602994
Update date: Jun. 21, 2024
Pradipta Ambara R
アンバラ プラディプタ | Pradipta Ambara R
Affiliation and department：
Job title：
Assistant Professor
Research field (1)：
Bioorganic chemistry
Research keywords (5)：
Bioscience Organic Chemistry
, Organic Analytical Chemistry
, Natural Product Organic Chemistry
, Organic Synthetic Chemistry
, Bioorganic Chemistry
Research theme for competitive and other funds (13)：
- 2024 - 2027 がん細胞内アクロレインおよび一酸化炭素の有機反応を利用した革新的がん治療法の開拓
- 2024 - 2025 内在性アクロレインを標的とした革新的がん診断法
- 2022 - 2025 有機パラジウムの反応性に基づくがん細胞 CO 検出及び化学療法への応用
- 2022 - 2025 生細胞染色法を用いた乳癌の乳房温存手術の切除断端に対する術中迅速診断の確立
- 2022 - 2025 乳癌における脂質メディエーターを標的とする薬物送達システムを用いた新規治療の開発
- 2021 - 2024 Reactivity of acrolein produced by cancer cells: Application to selective cancer therapy
- 2018 - 2023 (Chemical biology for controlling ubiquitin function
- 2018 - 2021 乳癌手術切除断端に対する生組織標本を用いた癌細胞の術中迅速診断の開発
- 2018 - 2021 In vivo Click Reaction of Acrolein: Application to In vivo Synthetic Chemistry and Cancer Imaging
- 2018 - 2020 Acrolein sensor for rapid and accurate intraoperative diagnosis of breast cancer morphology
- 2017 - 2020 生体内合成化学治療:動物内における毒性分子アクロレインから薬理活性複素環化合物への変換
- 2016 - 2018 Conversion of toxic acrolein into pharmacologically active heterocycles in live animals
- 2014 - 2017 生体内イミン[4+4]環化化合物によるエピジェネちエピジェネティクス制御の解明と制御
Show all
Papers (63)：
-
T. Kasahara, T.-C. Chang, H. Yoshioka, S. Urano, Y. Egawa, M. Inoue, T. Tahara, K. Morimoto, Ambara R. Pradipta, K. Tanaka. Anticancer approach by targeted activation of a global inhibitor of sialyltransferases with acrolein. Chemical Science. 2024
-
Yudai Ode, Ambara R. Pradipta, Akihiro Ishiwata, Akihiro Nambu, Kazunobu Ohnuki, Hiroshi Mizuma, Hiromitsu Haba, Katsunori Tanaka. Metallic radionuclide-labeled tetrameric 2,6-diisopropylphenyl azides for cancer treatment. Chemical Communications. 2024
-
Y. Ode, A. R. Pradipta, P. Ahmadi, A. Ishiwata, A. Nakamura, Y. Egawa, Y. Kusakari, K. Muguruma, Y. Wang, X. Yin, et al. Preclinical evaluation of the therapeutic potential of 211At-radiolabeled 2,6-diisopropylphenyl azide in mouse models of human lung cancer. RIKEN Accelerator Progress Report. 2023. 57
-
永橋昌幸, 服部彬, 浦野清香, 黒岩真美子, 小松美希, A. R. Pradipta, 盛本浩二, 田中克典, 三好康雄. 乳癌における脂質メディエーターの役割と臨床応用へ向けた取り組み. 乳癌基礎研究. 2023. 31. 27-33
-
Y. Ode, Ambara R. Pradipta, P. Ahmadi, A. Ishiwata, A. Nakamura, Y, Egawa, Y. Kusakari, K. Muguruma, Y. Wang, et al. Therapeutic efficacy of 211At-radiolabeled 2,6-diisopropylphenyl azide in mouse models of human lung cancer. Chemical Science. 2023. 14. 30. 8054-8060
ｍore...
Patents (3)：
-
腫瘍の治療剤
-
アクロレインのインビボクリック反応を利用した化学療法剤の送達と治療
-
アクロレインとの反応薬、その利用及び新規化合物
Lectures and oral presentations (166)：
-
From Outsider to Insider: Transforming Challenges into Impacts in Japanese Academia
(第14回 CSJ化学フェスタ 2024 2024)
-
Reactivity and Application of Cancer Metabolites for Therapy and Diagnosis
(BRIN Webinar: The Challenges and Solutions of Translating Drug Discovery from Nature into Successful Ventures 2024)
-
パラジウム触媒反応によるがん細胞内での内因性一酸化炭素を用いた抗がん活性分子の合成
(日本ケミカルバイオロジー学会 第18回年会 2024)
-
個別化医療を可能とする糖鎖アルブミンライブラリーの合成
(日本化学会第104春季年会 2024)
-
がん代謝物との[3+2]付加環化反応を利用したRI内用療法
(日本化学会第104春季年会 2024)
ｍore...
Education (4)：
- 2008 - 2011 Osaka University Graduate School of Science (Ph.D.) Department of Chemistry
- 2006 - 2008 Osaka University Graduate School of Science (M.Sc.) Department of Chemistry
- 2005 - 2006 Osaka University School of Science Department of Chemistry
- 1999 - 2003 Padjadjaran University Faculty of Mathematics and Natural Sciences (B.Sc.) Department of Chemistry
Professional career (1)：
Work history (8)：
- 2020/04 - 現在 Tokyo Institute of Technology School of Materials and Chemical Technology Assistant Professor
- 2020/07 - 2026/03 RIKEN Visiting Scientist (additional position)
- 2022/08 - 2023/07 Taiwan National Chung Hsing University Visiting Assistant Professor (additional position)
- 2017/04 - 2020/03 RIKEN Cluster for Pioneering Research Biofunctional Synthetic Chemistry Laboratory Special Postdoctoral Researcher
- 2015/04 - 2020/03 Tokyo Medical and Dental University Visiting Lecturer (additional position)
- 2012/04 - 2017/03 RIKEN Biofunctional Synthetic Chemistry Laboratory Postdoctoral Researcher
- 2011/04 - 2012/03 Osaka University Laboratory for Natural Product Chemistry (Fukase Research Group) Postdoctoral Researcher
- 2003/09 - 2005/08 Industrial experience
Show all
Awards (9)：
- 2024/06 - Innovation Design Platform, Office of Research and Innovation, Tokyo Tech Tokyo Tech Social Change Challenge Award 2024 (Encouragement Award) 内在性アクロレインを標的とした革新的がん診断法
- 2021/09 - Tokyo Institute of Technology Research Incentive Award 2021
- 2016/07 - RIKEN Letter of Appreciation from RIKEN President
- 2016/04 - The Chemical Society of Japan The 96th Annual Meeting Best Presentation Award
- 2016/03 - RIKEN RIKEN Researcher Incentive Award 2015
- 2014/01 - RIKEN Letter of Appreciation from RIKEN President
- 2013/07 - Best Poster Award The 1st Asian Conference for “MONODUKURI” Strategy by Synthetic Organic Chemistry
- 2011/04 - Osaka University Global Center of Excellence Program Fellowship
- 2005/10 - MEXT Scholarship
Show all
Association Membership(s) (4)：
Division of Biofunctional Chemistry, The Chemical Society of Japan
, The Society of Synthetic Organic Chemistry Japan
, Japanese Society for Chemical Biology
, The Chemical Society of Japan
