Rchr
J-GLOBAL ID：201701008874109896   Update date: Oct. 03, 2024

Yamamoto Yusuke

Yamamoto Yusuke | Yamamoto Yusuke
Affiliation and department：
National Cancer Center,Research Institute Laboratory of Integrative Oncology

About National Cancer Center,Research Institute Laboratory of Integrative Oncology


Job title： Unit leader
Research field  (1)： Tumor biology
Research keywords  (3)： 上皮組織 ,  cancer biology ,  Stem cells
Research theme for competitive and other funds  (12)：
  • 2024 - 2027 Comprehensive Understanding of Interstitial Cystitis through Single-cell Multi-omics Analysis and Biomarker Discovery
  • 2024 - 2027 ブタとシングルセル解析で挑むMWCNT肺疾患の病態解明
  • 2023 - 2026 Generation of pneumoconiosis atlas unraveling at 1-cell resolution
  • 2023 - 2026 Developing a pneumoconiosis atlas at the single-cell resolution
  • 2022 - 2026 Integrated analysis for mitochondrial morphology
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Papers (134)：
  • Mayu Shibata, Kosuke Yoshida, Akira Yokoi, Hironori Suzuki, Yusuke Yamamoto, Masami Kitagawa, Eri Asano-Inami, Yuko Yasui, Yuki Nishiko, Masato Yoshihara, et al. Elucidation of the role of XBP1 in the progression of complete hydatidiform mole to invasive mole through RNA-seq. Gynecologic oncology. 2024. 190. 189-199
  • Tomofumi Yamamoto, Jun Nakayama, Fumihiko Urabe, Kagenori Ito, Nao Nishida-Aoki, Masami Kitagawa, Akira Yokoi, Masahiko Kuroda, Yutaka Hattori, Yusuke Yamamoto, et al. Aberrant regulation of serine metabolism drives extracellular vesicle release and cancer progression. Cell reports. 2024. 43. 8. 114517-114517
  • Marta Prieto-Vila, Yusuke Yoshioka, Naoya Kuriyama, Akihiko Okamura, Yusuke Yamamoto, Asao Muranaka, Takahiro Ochiya. Adult cardiomyocytes-derived EVs for the treatment of cardiac fibrosis. Journal of extracellular vesicles. 2024. 13. 7. e12461
  • Takashi Uehara, Juntaro Matsuzaki, Hiroshi Yoshida, Yuto Ogawa, Junichiro Miura, Hitoshi Fujimiya, Yusuke Yamamoto, Junpei Kawauchi, Satoko Takizawa, Kan Yonemori, et al. Potential utility of pretreatment serum miRNAs for optimal treatment selection in advanced high-grade serous ovarian cancer. Japanese journal of clinical oncology. 2024
  • Yukari Nagao, Akira Yokoi, Kosuke Yoshida, Masami Kitagawa, Eri Asano-Inami, Tomoyasu Kato, Mitsuya Ishikawa, Yusuke Yamamoto, Hiroaki Kajiyama. Uterine leiomyosarcoma cell-derived extracellular vesicles induce the formation of cancer-associated fibroblasts. Biochimica et biophysica acta. Molecular basis of disease. 2024. 167103-167103
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MISC (192)：
  • 都倉 桃子, 椎野 翔, 高山 伸, 首藤 昭彦, 吉田 正行, 谷田部 恭, 山本 雄介. 遺伝子発現解析に基づいた乳がんの腫瘍内細胞不均一性に関する研究. 日本乳癌学会総会プログラム抄録集. 2024. 32回. 52-52
  • 吉田 康将, 横井 暁, 山本 雄介. 子宮平滑筋肉腫に対するマルチオミクス解析による新たな治療標的の探索. 臨床薬理の進歩. 2024. 45. 42-49
  • 長尾 有佳里, 横井 暁, 吉田 康将, 北川 雅美, 山本 雄介, 加藤 友康, 梶山 広明. 婦人科発癌の謎に迫る~ここまでわかった分子機序 子宮平滑筋肉腫における発がんメカニズム解析と新規治療戦略の同定. 日本婦人科腫瘍学会雑誌. 2024. 42. 2. 75-85
  • 鈴木 一弘, 横井 暁, 吉田 康将, 稲見 恵理, 北川 雅美, 山本 雄介, 北井 美穂, 植野 さやか, 須藤 保, 梶山 広明. プラチナ抵抗性卵巣癌克服に向けた細胞外小胞関連JAK/STAT経路解析(Overcoming platinum resistance of ovarian cancer regulating the activated JAK/STAT pathways via extracellular vesicles). 日本癌学会総会記事. 2023. 82回. 129-129
  • 占部 文彦, 木村 高弘, 山本 雄介, 落谷 孝広. 遺伝子スクリーニングを用いた前立腺癌におけるエクソソーム治療の開発(Screening for regulators of extracellular vesicle secretion in prostate cancer). 日本癌学会総会記事. 2023. 82回. 450-450
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Education (5)：
  • 2006 - 2008 Ph.D. (Molecular Physiology), Waseda University Graduate School Major in Integrative Bioscience and Biomedical Engineering Graduate School of Science and Engineering
  • 2006 - 2008 早稲田大学 大学院 博士課程 理工学研究科 生命理工
  • 2004 - 2006 M.Sc. (Molecular Physiology), Waseda University Graduate School Major in Integrative Bioscience and Biomedical Engineering Graduate School of Science and Engineering
  • 2004 - 2006 Waseda University
  • 2000 - 2004 Waseda university Department of education
Professional career (1)：
  • 理学 (早稲田大学)
Work history (8)：
  • 2021/10 - 現在 National Cancer Center Laboratory of Integrative Oncology Unit Leader
  • 2019/04 - 2021/09 National Cancer Center, Research Institute Division of Cellular Signaling Senior Staff Scientist
  • 2015/07 - 2019/03 National Cancer Center Research Institute Division of Molecular and Cellular Medicine Senior Staff Scientist
  • 2012/12 - 2015/06 Jackson laboratory Research Scientist
  • 2010/04 - 2012/12 Genome institute of Singapore Research Associate
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Committee career (1)：
  • 2022/01 - 現在 日本癌学会 評議員
Association Membership(s) (4)：
日本細胞外小胞学会 ,  International Society for Extracellular Vesicles (ISEV) ,  日本癌学会 ,  日本分子生物学会
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