Higuchi Takuma

ヒグチタクマ | Higuchi Takuma

Affiliation and department：
Job title：助教
Homepage URL (1)： http://www.kochi-u.ac.jp/kms/ct_mrc/academic/

Research field (1)： Medical biochemistry

Research keywords (5)： RNA modification , microRNA , RNA結合タンパク質 , hepatocellular carcinoma , 非アルコール性脂肪肝炎

Research theme for competitive and other funds (8)：

2023 - 2026 miRNA生合成阻害因子によるNASH発症・増悪化の新たな調節機構の解明
2018 - 2023 Preservation of mammalian genetic resources and study for the developmental mechanism using freeze-dried cells
2019 - 2022 The effect of RNA binding proteins on regulatory mechanisms of anti-fibrotic and anti-inflammatory miRNA biogenesis
2020 - 2021 RNA修飾によるがん抑制miRNA産生性制御機構の解明
2016 - 2019 Elucidation of molecular mechanisms through RNA-RNA binding protein network in physiological regulation and disease onset

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Papers (19)：

Todaka Hiroshi, Arikawa Mikihiko, Noguchi Tatsuya, Ichikawa Atsushi, Higuchi Takuma, Sakamoto Shuji, Sato Takayuki. Promoting effect of sigma-1 receptor on the skeletal muscle differentiation and regeneration(タイトル和訳中). The Journal of Physiological Sciences. 2024. 74. Suppl.2. 223-223
Susumu Muroya, Yuta Horiuchi, Kazuki Iguchi, Takuma Higuchi, Shuji Sakamoto, Koichi Ojima, Kazutsugu Matsukawa. Depth of Interbreed Difference in Postmortem Bovine Muscle Determined by CE-FT/MS and LC-FT/MS Metabolomics. Metabolites. 2024. 14. 5
Ken-ichi MATSUMOTO, Takuma HIGUCHI, Mirei UMEKI, Masafumi ONO, Shuji SAKAMOTO. Tenascin-X is increased with decreased expression of miR-378a-5p and miR-486-5p in mice fed a methionine-choline-deficient diet that induces hepatic fibrosis. Biomedical Research. 2024. 45. 2. 67-76
Sylvia Lai, Takuma Higuchi, Masayuki Tsuda, Yasunori Sugiyama, Keiko Morisawa, Taketoshi Taniguchi, Shuji Sakamoto. NF90-NF45 is essential for β cell compensation under obesity-inducing metabolic stress through suppression of p53 signaling pathway. Scientific reports. 2022. 12. 1. 8837-8837
Kaz Kawamura, Takuma Higuchi, Shigeki Fujiwara. YAF2-Mediated YY1-Sirtuin6 Interactions Responsible for Mitochondrial Downregulation in Aging Tunicates. Molecular and Cellular Biology. 2021. 41. 7

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MISC (46)：

戸高寛, 有川幹彦, 野口達哉, 市川厚, 樋口琢磨, 坂本修士, 佐藤隆幸. 認知症治療薬ドネペジルはSigma 1受容体を介して筋再生を促進する. 日本病態生理学会雑誌. 2021. 30. 2 (CD-ROM)
島倉秀勝, 島倉秀勝, 鶴井大幹, 坂本修士, 樋口琢磨, 伊從慶太, 下池健太, 阪口雅弘, 内山淳平. Search for Staphylococcus pseudintermedius molecule associated with atopic dermatitis in dogs. 日本細菌学雑誌(Web). 2020. 75. 1
鶴井大幹, 島倉秀勝, 内山淳平, 今西市朗, 今西市朗, 坂本修士, 樋口琢磨, 伊從慶太, 下池健太, 藤村正人, et al. Staphylococcus pseudintermediusのイヌアトピー性皮膚炎増悪因子の探索. 日本獣医学会学術集会講演要旨集. 2020. 163rd
岡村早穂, 本郷新, 田村慎之介, 赤木悟史, 竹中由布, 樋口琢磨, 坂本修士, 枝重圭祐, 井上梓, 松川和嗣. ウシ凍結乾燥体細胞を用いて作出した核移植胚におけるヒストンH3のメチル化および遺伝子発現解析. The Journal of Reproduction and Development. 2019. 65. Suppl. j143-j143
那須川忠弥, 内山淳平, 鶴井大幹, 坂本修士, 樋口琢磨, 伊從慶太, 下池健太, 島倉秀勝, 松崎茂展, 阪口雅弘. 犬アトピー性皮膚炎を悪化させるStaphylococcus pseudintermedius分子の探索. 日本細菌学雑誌. 2019. 74. 1. 140-140

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Lectures and oral presentations (1)：

Professional career (1)：

Awards (3)：

Association Membership(s) (3)：

THE RNA SOCIETY OF JAPAN , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY

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