Asamizu Shumpei

アサミズシュンペイ | Asamizu Shumpei

Affiliation and department：
Job title： Project Associate Professor

Research field (2)： Applied microbiology , Applied biochemistry

Research keywords (15)： Streptomyces , secondary metabolism , natural product biosynthesis , bacterial interaction , genome mining , stable isotope labeling , comparative metabolomics , comparative transcriptomics , 抗生物質 , Trojan horse antibiotic , siderophore , RiPPs , lipopeptide , aminocyclitol , bacterial alkaloid

Research theme for competitive and other funds (9)：

2024 - 2026 放線菌の分枝発生メカニズムの解析と応用
2024 - 2024 Biosynthesis of non-natural RiPP-type lipopeptides using enzymatic promiscuity and bioengineering
2018 - 2021 Biosynthesis and mechanistic analysis of Trojan-horse antibiotic from Streptomyces species
2018 - 2020 ミコール酸含有細菌の接触刺激による放線菌二次代謝応答機構の変異ゲノム解析を用いた解明
2018 - 2019 放線菌由来シデロマイシン系抗生物質の生合成及び作用機作解析

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Papers (46)：

Kimberly S. Taylor, Madison M. McMonagle, Schaelee C. Guy, Ariana M. Human-McKinnon, Shumpei Asamizu, Heidi J. Fletcher, Bradley W. Davis, Takashi L. Suyama. Albumin-ruthenium catalyst conjugate for bio-orthogonal uncaging of alloc group. Organic & Biomolecular Chemistry. 2024. 22. 15. 2992-3000
Shotaro Hoshino, Shinta Ijichi, Shumpei Asamizu, Hiroyasu Onaka. Insights into Arsenic Secondary Metabolism in Actinomycetes from the Structure and Biosynthesis of Bisenarsan. Journal of the American Chemical Society. 2023. 145. 32. 17863-17871
Fumihiro Ishikawa, Natsumi Tsukumo, Erika Morishita, Shumpei Asamizu, Saaya Kusuhara, Shinsuke Marumoto, Katsuki Takashima, Hiroyasu Onaka, Genzoh Tanabe. Biosynthetic diversification of non-ribosomal peptides through activity-based protein profiling of adenylation domains. Chemical Communications. 2023. 59. 62. 9473-9476
Toshiki Nagakubo, Shumpei Asamizu, Tatsuya Yamamoto, Manami Kato, Tatsuya Nishiyama, Masanori Toyofuku, Nobuhiko Nomura, Hiroyasu Onaka. Intracellular Phage Tail-Like Nanostructures Affect Susceptibility of Streptomyces lividans to Osmotic Stress. mSphere. 2023. 8. 3. e0011423
Shinta Ijichi, Shotaro Hoshino, Shumpei Asamizu, Hiroyasu Onaka. SolS-catalyzed sulfoxidation of labionin to solabionin drives antibacterial activity of solabiomycins. Bioorganic & Medicinal Chemistry Letters. 2023. 89. 129323

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MISC (16)：

Manami Kato, Shumpei Asamizu, Hiroyasu Onaka. Redox-active compound generated by bacterial crosstalk induces hypha branching in Streptomyces species. 2023
浅水俊平. ミコール酸含有細菌の接触刺激による放線菌二次代謝応答機構の変異ゲノム解析を用いた解明. Institute for Fermentation, Osaka. Research Communications. 2020. 34
尾仲宏康, 浅水俊平. Combined-culture: Antibiotic Production Induced by Microbial Physical Contact. Journal of Environmental Biotechnology (Web). 2020. 20. 1
菅井佳宣, 菅井佳宣, 尾崎太郎, 尾崎太郎, 浅水俊平, 尾仲宏康, 菅裕明, 後藤佑樹. Analysis of lanthipeptide biosynthetic enzymes responsible for formation of novel goadionin structure. Institute for Fermentation, Osaka. Research Communications. 2018. 32. 167-177
浅水俊平, 尾崎太郎, 菅井佳宣, 尾仲宏康, 佐々木槇子, 吉田昭介, 吉田昭介, 宮本憲二. RNA sequencing analysis of contact-dependent secondary metabolism responses by Streptomyces coelicolor. Institute for Fermentation, Osaka. Research Communications. 2018. 32. 87-94

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Lectures and oral presentations (91)：

Discovery of phage tail-like nanostructures associated with a host stress response and implication of their ecological impact.
(日本微生物生態学会大会(Web) 2023)
Signals from Nature: The Environmental Response of Actinomycetes via Pyrogallol
(日本微生物生態学会大会(Web) 2023)
Microbial chemical communications drive hyphal branching of actinomycetes
(日本放線菌学会大会講演要旨集 2023)
Exploration of arsenic secondary metabolic pathways distributed in actinomycetes
(日本放線菌学会大会講演要旨集 2023)
Sulfoxidation of labionin enhances antibacterial activity
(日本放線菌学会大会講演要旨集 2023)

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Education (4)：

2007 - 2010 Toyama Prefectural University
2005 - 2007 Toyama Prefectural University Graduate School of Engineering
2003 - 2005 Toyama Prefectural University
2001 - 2003 Toyama Prefectural University

Professional career (1)：

Ph.D. (Toyama Prefectural University)

Work history (7)：

2023/06 - 現在 Kobe University Engineering Biology Research Center Project Associate Professor
2023/04 - 2023/05 Gakushuin University Faculty of Science, Department of Life Science Project Researcher
2019/05 - 2023/03 The University of Tokyo Graduate School of Agricultural and Life Sciences
2013/05 - 2019/04 The University of Tokyo Graduate School of Agricultural and Life Sciences
2013/04 - 2013/04 The University of Tokyo Graduate School of Agricultural and Life Sciences Project Researcher

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Awards (6)：

2023/03 - 日本農芸化学会日本農芸化学会2023年度広島大会(第13回)トピックス賞放線菌におけるヒ素二次代謝経路に関する研究
2022/03 - JSBBA Hot Topics Award (12th) at Annual Meeting of JSBBA 2022 Biological significance of the phage tail-like nanostructures produced by soil bacteria.
2021/03 - JSBBA Hot Topics Award (11th) at Annual Meeting of JSBBA 2021 Analysis of fatty acyl chain biosynthesis in goadvionins.
2018/03 - JSBBA Hot Topics Award (9th) at Annual Meeting of JSBBA 2018 Analysis of lanthipeptide biosynthetic enzymes responsible for formation of novel labionen structure.
2016/09 - The Society for Actinomycetes Japan Hamada award

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Association Membership(s) (2)：

日本放線菌学会 , 日本農芸化学会

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