MURAKAMI Chiaki

ムラカミチアキ | MURAKAMI Chiaki

Affiliation and department：
Job title： Visiting Professor
Other affiliations (2)：

Chiba University Institute for Advanced Academic Research Project Assistant Professor
Chiba University Graduate School of Science Project Assistant Professor

Homepage URL (1)： https://scholar.google.com/citations?user=lgRQ9pwAAAAJ&hl=ja

Research field (1)： Functional biochemistry

Research keywords (15)： sphingolipids , glycerophospholipids , protein-protein interaction , 脂質代謝酵素 , biochemistry , LC-MS/MS , Phospholipase C , Phosphatidic acid phosphatase (PAP) , Sphingomyelin synthase-related protein (SMSr) , Diacylglycerol , Sphingomyelin synthase , Phosphatidic acid , Lipid signaling , diacylglycerol kinase , biochemistry of lipids

Research theme for competitive and other funds (26)：

2023 - 2028 生活習慣病とフレイルのリスクをシームレスに低減する画期的健康寿命延伸食品の開発
2024 - 2027 Characterization of novel mammalian phospholipase C & Diacylglycerol kinase
2024 - 2026 Characterization of novel mammalian phospholipase Cs
2024 - 2026 令和6年度日本人若手研究者研究助成金
2023 - 2026 Characterization of novel mammalian phospholipase C & Diacylglycerol kinase

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Papers (25)：

Rika Suzuki, Chiaki Murakami, Kamila Dilimulati, Kyoko Atsuta-Tsunoda, Takuma Kawai, Fumio Sakane. Human sphingomyelin synthase 1 generates diacylglycerol in the presence and absence of ceramide via multiple enzymatic activities. FEBS Letters. 2023
Masataka Furuta, Chiaki Murakami, Yuki Numagami, Rika Suzuki, Fumio Sakane. Diacylglycerol kinase ζ interacts with sphingomyelin synthase 1 and sphingomyelin synthase-related protein via different regions. FEBS open bio. 2023
Ayako Yamazaki, Ayane Kawashima, Takuya Honda, Takafumi Kohama, Chiaki Murakami, Fumio Sakane, Toshihiko Murayama, Hiroyuki Nakamura. Identification and characterization of diacylglycerol kinase ζ as a novel enzyme producing ceramide-1-phosphate. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2023. 159307-159307
Naoto Yachida, Fumi Hoshino, Chiaki Murakami, Masayuki Ebina, Yuri Miura, Fumio Sakane. Saturated fatty acid- and/or monounsaturated fatty acid-containing phosphatidic acids selectively interact with heat shock protein 27. Journal of Biological Chemistry. 2023. 299. 3. 103019-103019
Yuki Numagami, Fumi Hoshino, Chiaki Murakami, Masayuki Ebina, Fumio Sakane. Distinct regions of Praja-1 E3 ubiquitin-protein ligase selectively bind to docosahexaenoic acid-containing phosphatidic acid and diacylglycerol kinase δ. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2022. 159265-159265

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MISC (44)：

Dilimulati Kamila, Murakami Chiaki, Atsuta-Tsunoda Kyoko, Inomata Sho, Kawai Takuma, Sakane Fumio. Human sphingomyelin synthase 2 exhibit phosphatidylcholine/phosphatidylethanolamine phospholipase C activity(タイトル和訳中). 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-075]
村上千明, 堺弘道, 角田京子[熱田], Dilimulati Kamila, 川合巧真, 猪俣翔, 坂根郁夫. PHOSPHO1はホスファチジルコリンとホスファチジルエタノールアミンに対するホスホリパーゼC活性を持つ. 日本生化学会大会プログラム・講演要旨集. 2023. 96回. [1P-076]
Chiaki Murakami. 半世紀以上分子実体不明の哺乳類ホスホリパーゼC酵素群の同定. 2023
Chiaki Murakami, Hiromichi Sakai, Fumio Sakane. PHOSPHO1はホスファチジルコリンとホスファチジルエタノールアミンのホスホリパーゼC活性を持つ. 2023. 65. 65-68
山崎綾子, 本田拓也, 古浜孝文, 村上千明, 坂根郁夫, 中村浩之. ジアシルグリセロールキナーゼζはセラミドキナーゼ非依存的にセラミド-1-リン酸を産生する. 脂質生化学研究. 2023. 65. 188-190

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Lectures and oral presentations (16)：

Identification of new mammalian phospholipase Cs
(the 25th Enzyme Application Symposium 2024)
Human PHOSPHO1 displays phosphatidylcholine/phosphatidylethanolamine phospholipase C
(The regular meeting of the JBS Kanto Branch 2023 2023)
PHOSPHO1 displays phosphatidylcholine/phosphatidylethanolamine phospholipase C
(65th the Japanese Conference on the Biochemistry of Lipids 2023)
Where do substrates of diacylglycerol kinases come from?
(The 128th Annual Meeting of The Japanese Association of Anatomists 2023)
Mammalian sphingomyelin synthase-related protein is new type of phospholipase C
(Annual meeting of Japanese biochemical society 2021 2021)

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Works (1)：

Development of New Lipid Second Messenger Analytical Method Toward Green Chemistry from Chiba university
Chiaki Murakami 2019 -

Education (3)：

2018 - 2021 Chiba university Graduate School of Science and Engineering Department of Chemistry
2016 - 2018 Chiba university Graduate School of Science Department of Chemistry
2012 - 2016 Chiba University Faculty of Science Department of Chemistry

Professional career (3)：

Ph.D. (Science) (Chiba University)
Master of Science (Chiba University)
Bachelor of Science (Chiba University)

Work history (5)：

2024/04 - 現在 Japan Society for the Promotion of Science JSPS Scientist for Joint International Research
2022/05 - 現在 Chiba University Graduate School of Science Project Assistant Professor
2022/05 - 現在 Chiba University Institute for Advanced Academic Research Assistant Professor
2021/04 - 2022/04 Japan Society for the Promotion of Science JSPS Research Fellow (PD)
2018/04 - 2021/03 Japan Society for the Promotion of Science JSPS Research Fellow (DC1)

Awards (11)：

2024/06 - Amano Enzyme Foundation for Science and Technology the 25th Enzyme Application Symposium Research Incentive Award Identification of new mammalian phospholipase Cs
2021/11 - The Japanese Biochemical Society Young Scientist Award (The 94th Annual Meeting of the Japanese Biochemical Society) Mammalian sphingomyelin synthase-related protein displays phospholipase C activity
2021/03 - Chiba University Chiba University President’s Award for Outstanding Students
2021/03 - Chiba University Dean’s Award for Outstanding Students (Doctoral Course), Graduate School of Science 2021
2020/08 - Young Researchers Society for Biochemistry (Japan) Best Presentation Award Mammalian sphingomyelin synthase-related protein shows phosphatidic acid phosphatase activity

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Association Membership(s) (4)：

THE JAPANESE BIOCHEMICAL SOCIETY , 生化学若い研究者の会 , The American Society for Biochemistry and Molecular Biology , THE JAPANESE CONFERENCE ON THE BIOCHEMISTRY OF LIPIDS

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