Rchr
J-GLOBAL ID：201701011123049120   Update date: Jul. 16, 2024

Yamakoshi Hiroyuki

ヤマコシ ヒロユキ | Yamakoshi Hiroyuki
Affiliation and department：
Tohoku University Research Center for Pharmaceutical Development and Central Analytical Center, Graduate School of Pharmaceutical Sciences

About Tohoku University Research Center for Pharmaceutical Development and Central Analytical Center, Graduate School of Pharmaceutical Sciences


Job title： Assistant Professor
Homepage URL  (1)： http://www.phar.nagoya-cu.ac.jp/hp/ygk/index.html
Research field  (3)： Bioorganic chemistry ,  Structural/physical organic chemistry ,  Pharmaceuticals - chemistry and drug development
Research keywords  (4)： imaging ,  chemical biology ,  bioactive natural products ,  Synthetic organic chemistry
Research theme for competitive and other funds  (8)：
  • 2022 - 2025 ラマンプローブによる可逆的チアMichael反応の生細胞解析
  • 2022 - 2025 有機ニトロキシルラジカルー遷移金属協奏触媒の機能創成を機軸とする精密有機分子構築
  • 2019 - 2022 Studies on the synthesis of kadcoccilactone A
  • 2016 - 2019 Studies on the synthesis of scillascilloside E-1
  • 2014 - 2016 Studies on the synthesis of marine alkaloid spirolide D
Show all
Papers (62)：
  • Hiroyuki Yamakoshi, Michihiro Fukuda, Hiro Ikeda, Shogo Fujiki, Aki Kohyama, Shota Nagasawa, Hanae Shinozaki, Hiroyuki Shibata, Yoshiharu Iwabuchi. Design, Synthesis, and Biological Evaluation of Water-Soluble Prodrugs of C5-Curcuminoid GO-Y030 Based on Reversible Thia-Michael Reaction. Chemical and Pharmaceutical Bulletin. 2024. 72. 1. 127-134
  • Takashi MaruYama, Hiroyuki Yamakoshi, Yoshiharu Iwabuchi, Hiroyuki Shibata. Mono-Carbonyl Curcumin Analogs for Cancer Therapy. Biological and Pharmaceutical Bulletin. 2023. 46. 6. 756-763
  • Hiroyuki Yamakoshi, Jun Ando, Syusuke Egoshi, Kosuke Dodo, Mikiko Sodeoka, Katsumasa Fujita. Raman Imaging and Screening of Bioactive Small Molecules. Raman Spectroscopy in Human Health and Biomedicine. 2023. 271-298
  • Hiroyuki Yamakoshi, Daiki Shibata, Kazuki Bando, Shinji Kajimoto, Aki Kohyama, Syusuke Egoshi, Kosuke Dodo, Yoshiharu Iwabuchi, Mikiko Sodeoka, Katsumasa Fujita, et al. Ratiometric analysis of reversible thia-Michael reactions using nitrile-tagged molecules by Raman microscopy. Chemical Communications. 2023
  • Kimihiro Noguchi, Sayuri Saito, Hiroyuki Yamakoshi, Seiichi Nakamura. Stereoselective Synthesis of the DE Ring Portion of Kadcoccilactone A by a Radical Addition/Cyclization Approach. European Journal of Organic Chemistry. 2022. 2022. 45
ｍore...
MISC (20)：
ｍore...
Patents (1)：
  • ビス(アリールメチリデン)アセトン化合物、抗癌剤、発癌予防剤、Ki-Ras、ErbB2、c-Myc及びCyclinD1の発現抑制剤、β-カテニン分解剤並びにp53の発現増強剤
Books (1)：
  • 実験医学増刊号
    羊土社 2012
Education (2)：
  • 2005 - 2010 Tohoku University Graduate School of Pharmaceutical Sciences
  • - 2005 Tohoku University Faculty of Pharmaceutical Sciences
Professional career (1)：
  • 東北大学大学院薬学研究科創薬化学専攻/博士(薬学)
Work history (5)：
  • 2020/07 - 現在 Tohoku University Graduate School of Pharmaceutical Sciences Research Center for Pharmaceutical Development
  • 名古屋市立大学薬学研究科助教
  • 理化学研究所客員研究員
  • 日本科学技術振興機構ERATO袖岡生細胞分子化学プロジェクト博士研究員
  • 日本学術振興会特別研究員
Association Membership(s) (5)：
The Chemical Society of Japan ,  The Japanese Association for Molecular Target Therapy of Cancer ,  Japanese Society for Chemical Biology ,  The Society of Synthetic Organic Chemistry, Japan ,  The Pharmaceutical Society of Japan
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page

TOP

BOTTOM