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J-GLOBAL ID:201701011450882065   Update date: Oct. 24, 2024

Otani Tetsuhisa

オオタニ テツヒサ | Otani Tetsuhisa
Affiliation and department:
Other affiliations (1):
  • Japan Science and Technology Agency
Homepage URL  (1): https://www.biol.se.tmu.ac.jp/faculty.asp?otani
Research field  (2): Developmental biology ,  Cell biology
Research keywords  (4): 上皮恒常性 ,  Epithelial Barrier ,  Tight Junction ,  Cell Adhesion
Research theme for competitive and other funds  (12):
  • 2021 - 2026 細胞間接着を起点とした細胞競合の分子機構とその生理的制御機構の解明
  • 2024 - 2026 細胞間接着装置による創傷治癒応答の空間スケールの制御機構の解明
  • 2020 - 2023 接着と張力の操作で明らかにする上皮ダイナミクス
  • 2018 - 2021 Modular organization of tight junctions and its roles in epithelial plasticity
  • 2019 - 2021 上衣細胞間接着の異常を起点とした水頭症発症機構の解明
Show all
Papers (31):
  • Kaoru Sugimura, Tetsuhisa Otani. Vertex remodeling during epithelial morphogenesis. Current Opinion in Cell Biology. 2024. 91. 102427-102427
  • Eriko Deguchi, Shuhao Lin, Daiki Hirayama, Kimiya Matsuda, Akira Tanave, Kenta Sumiyama, Shinya Tsukiji, Tetsuhisa Otani, Mikio Furuse, Alexander Sorkin, et al. Low-affinity ligands of the epidermal growth factor receptor are long-range signal transmitters during collective cell migration of epithelial cells. bioRxiv. 2024
  • Sayuki Hirano, Yohei Kondo, Noriyuki Kinoshita, Tetsuhisa Otani, Mikio Furuse, Naoto Ueno, Kazuhiro Aoki. ZO-1 shuttles between tight junctions and podosomes by riding ERK activation waves during collective cell migration. bioRxiv. 2024
  • Thanh Phuong Nguyen, Tetsuhisa Otani, Motosuke Tsutsumi, Noriyuki Kinoshita, Sachiko Fujiwara, Tomomi Nemoto, Toshihiko Fujimori, Mikio Furuse. Tight junction membrane proteins regulate the mechanical resistance of the apical junctional complex. Journal of Cell Biology. 2024
  • Shuhei Kuno, Ryu Nakamura, Tetsuhisa Otani, Hideru Togashi. Multivalent Afadin Interaction Promotes IDR-Mediated Condensate Formation and Junctional Separation of Epithelial Cells. bioRxiv. 2024
more...
MISC (2):
Education (2):
  • 2000 - 2005 京都大学大学院 生命科学研究科 統合生命科学専攻
  • 1996 - 2000 Kyoto University Faculty of Science Faculty of Science
Professional career (1):
  • 博士(生命科学) (京都大学)
Work history (5):
  • 2023/10 - 現在 Tokyo Metropolitan University
  • 2020/11 - 現在 Japan Science and Technology Agency
  • 2015/10 - 2023/09 National Institute for Physiological Sciences Division of Cell Structure Assistant Professor
  • 2007/04 - 2015/09 RIKEN CDB Laboratory for Morphogenetic Signaling
  • 2005/04 - 2007/03 RIKEN CDB Laboratory for Cell Adhesion and Tissue Patterning
Awards (4):
  • 2021/09 - 4th International Tight Junction Conference Poster award
  • 2012/05 - 第45回日本発生生物学会・第64回日本細胞生物学会合同年会 優秀ポスター賞
  • 2010/05 - 第62回日本細胞生物学会大会 若手優秀発表賞
  • 2007/03 - 第5回国際学生セミナー 最優秀発表賞
Association Membership(s) (4):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  JAPANESE SOCIETY OF DEVELOPMENTAL BIOLOGISTS ,  JAPAN SOCIETY FOR CELL BIOLOGY ,  The American Society for Cell Biology
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