Research theme for competitive and other funds (4):
2020 - 2023 Development of innovative treatment for multiple sclerosis based on control of neurodegeneration and inflammation by applying function of LOTUS
2018 - 2021 神経再生機能分子LOTUSによるALS の治療法開発
2018 - 2020 development of biomarker for disease activity of multiple sclerosis
2016 - 2018 Elucidation of pathogenesis and development of new therapy for neurological disorder in multiple sclerosis
Papers (65):
Takuya Ikeda, Keita Takahashi, Minatsu Higashi, Hiroyasu Komiya, Tetsuya Asano, Akihiro Ogasawara, Shun Kubota, Shunta Hashiguchi, Misako Kunii, Kenichi Tanaka, et al. Lateral olfactory tract usher substance (LOTUS), an endogenous Nogo receptor antagonist, ameliorates disease progression in amyotrophic lateral sclerosis model mice. Cell death discovery. 2023. 9. 1. 454-454
Taishi Wada, Hiroshi Doi, Masaki Okubo, Mikiko Tada, Naohisa Ueda, Hidefumi Suzuki, Wakana Tominaga, Haruki Koike, Hiroyasu Komiya, Shun Kubota, et al. RNA foci in two bi-allelic RFC1 expansion carriers. Annals of neurology. 2023