Inaba Hironori

イナバヒロノリ | Inaba Hironori

Homepage URL (1)： https://www.medic.mie-u.ac.jp/organization/course/kaibo/

Research field (2)： Anatomy , Cell biology

Research keywords (3)：クライオ電子線トモグラフィー , 光遺伝学 , 細胞生物学

Research theme for competitive and other funds (4)：

2022 - 2025 Analyses on RhoA-induced intracellular calcium signaling using optogenetics
2018 - 2019 RAC1光スイッチによるアクチン重合・分岐の急速凍結クライオ電子線トモグラフィー
2018 - 2019 シグナル分子の光操作による上皮細胞集団遊走機構の解析
ホスホリパーゼCεによる一次線毛退縮制御機構の解明

Papers (7)：

Hiroshi Hanafusa, Shin Kedashiro, Mako Gotoh, Ko-Hei Saitoh, Hironori Inaba, Tomoki Nishioka, Kozo Kaibuchi, Masaki Inagaki, Naoki Hisamoto, Kunihiro Matsumoto. LRRK1-mediated NDEL1 phosphorylation promotes cilia disassembly via dynein-2-driven retrograde intraflagellar transport. Journal of cell science. 2022. 135. 21
Hironori Inaba, Qianqian Miao, Takao Nakata. Optogenetic control of small GTPases reveals RhoA mediates intracellular calcium signaling. Journal of Biological Chemistry. 2021. 296. 100290-100290
Takanobu Shimizu, Takeshi Nakamura, Hironori Inaba, Hiroaki Iwasa, Junichi Maruyama, Kyoko Arimoto-Matsuzaki, Takao Nakata, Hiroshi Nishina, Yutaka Hata. The RAS-interacting chaperone UNC119 drives the RASSF6-MDM2-p53 axis and antagonizes RAS-mediated malignant transformation. The Journal of biological chemistry. 2020. 295. 32. 11214-11230
Hironori Inaba, Daishi Yamakawa, Yasuko Tomono, Atsushi Enomoto, Shinji Mii, Kousuke Kasahara, Hidemasa Goto, Masaki Inagaki. Regulation of keratin 5/14 intermediate filaments by CDK1, Aurora-B, and Rho-kinase. Biochemical and Biophysical Research Communications. 2018. 498. 3. 544-550
Hironori Inaba, Koji Yoda, Hiroyuki Adachi. The F-actin-binding RapGEF GflB is required for efficient macropinocytosis in Dictyostelium. Journal of Cell Science. 2017. 130. 18. 3158-3172

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MISC (4)：

Optogenetic manipulations of small GTPases and observations of their intracellular functions. 2021. 56. 2. 59-63
Hidemasa Goto, Hironori Inaba, Masaki Inagaki. Mechanisms of ciliogenesis suppression in dividing cells. Cell. Mol. Life Sci. 2017. 74. 5. 881-890
稲葉弘哲, 後藤英仁, 笠原広介, 熊本香奈子, 米村重信, 猪子誠人, 何東偉, 五島直樹, 山野荘太郎, 鰐渕英機, et al. Ndel1はtrichoplein-Aurora A経路の制御によって増殖細胞の線毛形成を抑制する. 日本癌学会総会記事. 2016. 75回. P-3100
稲葉弘哲, 後藤英仁, 笠原広介, 熊本香奈子, 米村重信, 猪子誠人, 何東偉, 五島直樹, 山野荘太郎, 鰐渕英機, et al. 細胞骨格、形態、運動を制御する分子機構 Ndel1は増殖細胞において一次線毛形成を抑制する. 日本細胞生物学会大会講演要旨集. 2016. 68回. 40-40

Books (1)：

Lectures and oral presentations (22)：

低分子量Gタンパク質の光遺伝学的制御により明らかとなったRhoAによる細胞内カルシウムシグナル制御
(第126回日本解剖学会総会・全国学術集会 / 第98回日本生理学会大会合同大会 2021)
Optogenetic control of small GTPases reveals RhoA-mediated intracellular calcium signaling
(Cell Bio Virtual 2020 - An Online ASCB/EMBO Meeting 2020)
Analyses of the regulation of PLCε activity by small GTPases using optogenetics
(The 72nd Annual Meeting of the Japan Society for Cell Biology 2020)
Analyses on the intracellular Ca2+ signaling regulated by RhoA using optogen etics
(Joint Annual Meeting of 71st JSCB & 19th PSSJ 2019)
CDK1によるケラチン5のリン酸化が皮膚基底層上皮細胞の細胞分裂に必要である
(日本細胞生物学会大会講演要旨集 2017)

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Education (2)：

Professional career (1)：

Work history (3)：

2022/03 - 現在 Mie University Graduate School of Medicine, Department of Histology and Cell Biology Lecturer
2017/01 - 2022/02 Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Bio-Matrix Cell Biology Assistant Professor
2013/04/01 - 2016/12/31 Aichi Cancer Center Research Institute Division of Biochemistry Research resident

Awards (2)：

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