Kashio Makiko

カシオマキコ | Kashio Makiko

Affiliation and department：
Job title： Associate professor

Research field (2)： Clinical pharmacy , Physiology

Research keywords (3)： Physiology , Temperature , TRP channel

Research theme for competitive and other funds (5)：

2020 - 2023 体温と代謝をつなぐ体温センサーTRPM2機能制御機構の解明
2017 - 2020 Molecular basis of basolateral CALHM channel sorting in epithelial cells
2016 - 2019 Neurotransmission of sensory information through CALHM ion channels
2015 - 2017 Heteromeric CALHM1/3 in neurotransmission of taste cells
2013 - 2015 Physiological roles of TRPM2 in microglial functions

Papers (26)：

Makiko Kashio, Sandra Derouiche, Reiko U Yoshimoto, Kenji Sano, Jing Lei, Mizuho A Kido, Makoto Tominaga. Involvement of TRPV4 in temperature-dependent perspiration in mice. eLife. 2024
Makiko Kashio. TRP channels and thermoregulation; therapeutic opportunities. 2024
Makiko Kashio, Makoto Tominaga. Role of novel de novo gain-of-function TRPM3 mutations in a spectrum of neurodevelopmental disorders. Cell calcium. 2023. 110. 102704-102704
Makiko Kashio, Satoru Masubuchi, Makoto Tominaga. Protein kinase C-mediated phosphorylation of transient receptor potential melastatin type 2 Thr738 counteracts the effect of cytosolic Ca2+ and elevates the temperature threshold. The Journal of physiology. 2022. 600. 19. 4287-4302
Makiko Kashio, Makoto Tominaga. TRP channels in thermosensation. Current opinion in neurobiology. 2022. 75. 102591-102591

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MISC (10)：

加塩麻紀子. Thermosensitive-TRP channels detecting environmental/internal temperatures, and their physiological functions. 月刊メディカル・サイエンス・ダイジェスト. 2024. 50. 1
加塩麻紀子. 温度・機械刺激受容の最前線 1 温度感受性TRPチャネル-温度変化の受容から体温下機能まで. 生物の科学遺伝. 2024. 78. 2
富永真琴, 加塩麻紀子. Mechanisms Underlying Thermosensation. Brain and Nerve. 2022. 74. 2
加塩麻紀子, NGUYEN Thi Hong Dung, CHAPMAN Stella, 齋藤くれあ, STROM Tatjana, STROM Tatjana, 安井美桜, 安井美桜, 富永真琴. Single amino acids set apparent temperature thresholds for heat-evoked activation of mosquito transient receptor potential channel TRPA1. Pain Research. 2022. 37. 4
内田邦敏, 加塩麻紀子. エネルギー代謝調節におけるTRPチャネルの役割. 医学のあゆみ. 2019. 270. 10

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Books (1)：

Chapter 31 - TRP channels and thermoregulation; therapeutic opportunities
2024 ISBN:9780443186530

Lectures and oral presentations (29)：

Multiple pathways regulating TRPM2 activity at body temperature
(2024)
痛覚受容の末梢機構;現在地と今後の課題
(第129回日本解剖学会総会・全国学術集会 2024)
Functional interaction between TRPM2 and IKCa1 ion channels in mouse microglia.
(2023)
A new perspective in the study of TRPM2, a body temperature sensor.
(2023)
TRPM2 as a body temperature sensor.
(Ion channel modulation symposium 2023)

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Education (3)：

2008 - 2011 SOKENDAI (The Graduate University for Advanced Studies) School of Life Science Department of Physiological Science
2000 - 2002 Hiroshima University
1996 - 2000 Hiroshima University Faculty of Medicine Institute of Pharmaceutical Sciences

Professional career (1)：

Work history (7)：

2024/04 - 現在 Kumamoto University Department of Cell Physiology, Faculty of Life Sciences Associate Professor
2021/04 - 2024/03 National Institute for Physiological Sciences
2017/04 - 2021/03 Aichi Medical University Department of Physiology Assistant Professor
2014/09 - 2017/03 Kyoto Prefectural University of Medicine Department of Molecular Cell Physiology Assistant Professor
2013/08 - 2014/08 Okazaki Institute for Integrative Bioscience Division of Cell Signaling Postdoctoral fellow

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Awards (3)：

2016/03 - Physiological Society of Japan Irisawa Memorial Promotion Award for Young Physiologists
2012/06 - 4th International Congress on Cell Membranes and Oxidative Stress: Focus on Calcium Signaling and TRP Channels Poster award
2012/05 - 日本生化学会中部支部奨励賞

Association Membership(s) (4)：

日本生化学会 , 日本神経科学学会 , THE PHYSIOLOGICAL SOCIETY OF JAPAN , THE JAPANESE ASSOCIATION FOR THE STUDY OF TASTE AND SMELL

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