Research theme for competitive and other funds (7)：
2024 - 2027 Identification of therapeutic targets for heart failure and development of intervention methods related to the control mechanism of cardiac pump function
2017 - 2020 Development of novel therapeutic strategy for ischemic heart diseases through targeting protein degradation
2015 - 2017 Unraveling the mechanism by which G0S2 regulates mitochondrial ATP production under ischemia
2013 - 2015 Analysis of a novel mitochondrial protein AMF in energy metabolism
2009 - 2011 急性炎症における血管内皮細胞の細胞骨格ダイナミクス制御機構の解明
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Papers (40)：
Yusuke Katsuma, Isao Matsui, Ayumi Matsumoto, Hiroki Okushima, Atsuhiro Imai, Yusuke Sakaguchi, Takeshi Yamamoto, Masayuki Mizui, Shohei Uchinomiya, Hisakazu Kato, et al. Endogenous activation of peroxisome proliferator-activated receptor alpha in proximal tubule cells in counteracting phosphate toxicity. American journal of physiology. Renal physiology. 2024
Shinji Tokuyama, Hisakazu Kato, Hidekazu Takahashi, Kyoko Ueda, Asami Arita, Ryuta Ueda, Hiroto Seto, Yuki Sekido, Tsuyoshi Hata, Atsushi Hamabe, et al. BRAF V600E-induced distinct DNA damage response defines the therapeutic potential of p53 activation for TP53 wild-type colorectal cancer. Carcinogenesis. 2024
Mengying Cui, Koji Yamano, Kenichi Yamamoto, Hitomi Yamamoto-Imoto, Satoshi Minami, Takeshi Yamamoto, Sho Matsui, Tatsuya Kaminishi, Takayuki Shima, Monami Ogura, et al. HKDC1, a target of TFEB, is essential to maintain both mitochondrial and lysosomal homeostasis, preventing cellular senescence. Proceedings of the National Academy of Sciences. 2024. 121. 2
Hironori Yamamoto, Yohei Miyashita, Hitoshi Minamiguchi, Kazuyoshi Hosomichi, Shohei Yoshida, Hidetaka Kioka, Haruki Shinomiya, Haruno Nagata, Kenji Onoue, Masato Kawasaki, et al. Human leukocyte antigen-DQ risk heterodimeric haplotypes of left ventricular dysfunction in cardiac sarcoidosis: an autoimmune view of its role. Scientific reports. 2023. 13. 1. 19767-19767
Tatsuro Hitsumoto, Osamu Tsukamoto, Ken Matsuoka, Junjun Li, Li Liu, Yuki Kuramoto, Shuichiro Higo, Shou Ogawa, Noboru Fujino, Shohei Yoshida, et al. Restoration of Cardiac Myosin Light Chain Kinase Ameliorates Systolic Dysfunction by Reducing Superrelaxed Myosin. Circulation. 2023. 147. 25. 1902-1918
Hisakazu Kato, Hidetaka Kioka, Yoshihiro Asano, Seiji Takashima. Evaluation of Mitochondrial ATP Levels In Vivo Identifies G0/G1 Switch Gene 2 as a Therapeutic Target of Ischemic Heart Failure. JOURNAL OF CARDIAC FAILURE. 2014. 20. 10. S198-S198
