Nakahira Kiichi

Affiliation and department：
Job title： Associate Professor
Other affiliations (1)：

Weill Cornell Medicine Medicine Adjunct Assistant Professor of Medicine

Research field (1)： Experimental pathology

Research keywords (9)： COVID-19 , intensive care , sepsis , COPD , mitochondrial fusion and fission , autophagy , inflammasome , heteroplasmy , mitochondria

Research theme for competitive and other funds (6)：

2023 - 2026 超らせん構造型ミトコンドリアDNAの敗血症における機能的役割の解明
2020 - 2023 伸展負荷による血管平滑筋細胞死での転写因子Nr4aの役割解明と動脈解離予防薬開発
2020 - 2023 The role of mitochondrial heteroplasmy in sepsis
2017 - 2019 Mitochondrial Heteroplasmy in Sepsis
2016 - 2018 Heteroplasmic Mitochondrial DNA Mutation in Sepsis

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Papers (70)：

Kuei-Pin Chung, Chih-Ning Cheng, Yi-Jung Chen, Chia-Lang Hsu, Yen-Lin Huang, Min-Shu Hsieh, Han-Chun Kuo, Ya-Ting Lin, Yi-Hsiu Juan, Kiichi Nakahira, et al. Alveolar epithelial cells mitigate neutrophilic inflammation in lung injury through regulating mitochondrial fatty acid oxidation. Nature communications. 2024. 15. 1. 7241-7241
Akihiko Tanaka, Katsuki Wakayama, Yosuke Fukuda, Shin Ohta, Tetsuya Homma, Koichi Ando, Yuji Nishihara, Ryuichi Nakano, Jing Zhao, Yuki Suzuki, et al. Increased levels of circulating cell-free DNA in COVID-19 patients with respiratory failure. Scientific reports. 2024. 14. 1. 17399-17399
Kuei-Pin Chung, Jia-Ying Su, Yi-Fu Wang, Bugi Ratno Budiarto, Yu-Chang Yeh, Jui-Chen Cheng, Li-Ta Keng, Yi-Jung Chen, Ya-Ting Lu, Yi-Hsiu Juan, et al. Immunometabolic features of natural killer cells are associated with infection outcomes in critical illness. Frontiers in immunology. 2024. 15. 1334882-1334882
Yoji Kyotani, Jing Zhao, Kiichi Nakahira, Masanori Yoshizumi. The role of antipsychotics and other drugs on the development and progression of neuroleptic malignant syndrome. Scientific reports. 2023. 13. 1. 18459-18459
Wei Song, Haixi Zhang, Fan Yang, Kiichi Nakahira, Cheng Wang, Keqian Shi, Ruoyu Zhang. Single cell profiling of γδ hepatosplenic T-cell lymphoma unravels tumor cell heterogeneity associated with disease progression. Cellular oncology (Dordrecht). 2023. 46. 1. 211-226

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MISC (28)：

趙晶, 中平毅一, 京谷陽司, 吉栖正典. 高血圧を模倣した伸展刺激による血管平滑筋細胞死での転写因子NR4A1の保護作用について. 日本循環薬理学会口演要旨集. 2024. 33rd
趙晶, 中平毅一, 京谷陽司, 吉栖正典. 急激な高血圧を模した伸展刺激による血管平滑筋細胞死における転写因子NR4A1の役割について. 日本循環薬理学会口演要旨集. 2023. 32nd
趙晶, 中平毅一, 京谷陽司, 吉栖正典. 急激な伸展刺激によるラット血管平滑筋細胞死におけるNR4A1の保護作用について. 日本薬理学雑誌. 2022. 157. Supplement
趙晶, 中平毅一, 京谷陽司, 吉栖正典. ラット大動脈平滑筋の伸展刺激誘導性細胞死におけるiNOSの保護作用. 日本薬理学雑誌. 2021. 156. Supplement
趙晶, 中平毅一, 京谷陽司, 吉栖正典. 転写因子NR4A1は伸展負荷による血管平滑筋細胞死を抑制する. 日本循環薬理学会口演要旨集. 2021. 31st

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Lectures and oral presentations (7)：

Mitofusin1 regulates innate immune responses by inhibiting the accumulation of mitochondrial DNA mutation in sepsis
(The 95th Annual Meeting of the Japanese Pharmacological Society 2022)
Medication error
(The Nursing Pharmacology Conference 2021 in Nara 2021)
The role of mitochondria on pulmonary diseases and critical care illness
(2020)
Measuring the Mitochondrial Danger Signal Extracellular mitochondrial DNA in plasma
(American Thoracic Society International Conference 2018)
Carbon monoxide in the treatment of sepsis
(Asian Critical Care Conference and 37th the Korean Society of Critical Care Medicine Annual Congress, Seoul, South Korea 2018)

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Education (2)：

1999 - 2003 Okayama University Graduate School of Medicine , Dentistry and Pharmaceutical Sciences
1991 - 1997 Okayama University Medical School Faculty of Medicine

Professional career (2)：

MD (Okayama University Medical School)
PhD (Okayama University Medical School)

Work history (9)：

2020/04 - 現在 Nara Medical University Department of Pharmacology, Faculty of Medicine Associate Professor
2019/03 - 現在 Weill Cornell Medical College, New York, NY Department of Medicine Adjunct Assistant Professor of Medicine
2019/04 - 2020/03 Nara Medical University Department of Pharmacology Lecturer
2019/03 - 2019/03 Nara Medical University Department of Pharmacology Research Assistant Professor
2016/03 - 2019/03 Weill Cornell Medical College, New York, NY Department of Medicine Assistant Professor in Medicine

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Committee career (1)：

2022/03 - 2022/12 The 96th Annual Meeting of the Japanese Pharmacological Society Program committee

Awards (1)：

2022/03 - The 95th Annual Meeting of the Japanese Pharmacological Society Excellent Presentation Award Mitofusin1 regulates innate immune responses by inhibiting the accumulation of mitochondrial DNA mutation in sepsis

Association Membership(s) (2)：

American Thoracic Society , THE JAPANESE PHARMACOLOGICAL SOCIETY

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