Rchr
J-GLOBAL ID:201701013503659820
Update date: Jan. 31, 2024
Murakoshi Hideji
ムラコシ ヒデジ | Murakoshi Hideji
Affiliation and department:
Homepage URL (1):
http://www.nips.ac.jp/multiphoton/
Research field (2):
Neuroscience - general
, Biophysics
Research keywords (4):
光応答性タンパク質
, FRET
, 蛍光寿命イメージング
, 2光子顕微鏡
Research theme for competitive and other funds (13):
- 2022 - 2025 新規シナプティックオプトジェネティクスによる記憶保存様式の解明
- 2021 - 2023 光応答性CaMKIIによるiPlasticityの分子メカニズムの解明
- 2019 - 2021 シンギュラリティシナプスの探索と機能解析
- 2018 - 2021 Understanding Memory Storage Mechanism through Optical Manipulation of Synaptic States
- 2018 - 2020 Development and application of photoactivatable molecules for single-pathway activation
- 2018 - 2020 個体動物における組織深部分子活性化イメージングのための新規蛍光タンパク質の開発
- 2016 - 2018 “無蛍光”蛍光タンパク質で実現する組織深部分子活性化イメージング
- 2016 - 2018 新規分子活性操作法によるシナプスダイナミズムの意義の解明
- 2016 - 2018 Development of a new optogenetic tools and its application toward the understanding of the mechanism of signal transduction
- 2015 - 2018 Revealing the synaptic memory system by a new light sensitive signaling molecules
- 2014 - 2016 シナプス内状態揺らぎによる反応モジュレーションと機能連関
- 2014 - 2016 Development of a method to activate specific signaling pathway.
- 2012 - 2014 シナプス内分子数揺らぎが可塑性誘起に与える影響
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Papers (27):
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Shotaro Tsujioka, Ayumi Sumino, Yutaro Nagasawa, Takashi Sumikama, Holger Flechsig, Leonardo Puppulin, Takuya Tomita, Yudai Baba, Takahiro Kakuta, Tomoki Ogoshi, et al. Imaging single CaMKII holoenzymes at work by high-speed atomic force microscopy. Science advances. 2023. 9. 26. eadh1069
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Hideji Murakoshi, Hiromi H. Ueda, Ryuichiro Goto, Kosuke Hamada, Yutaro Nagasawa, Takao Fuji. In vivo three- and four-photon fluorescence microscopy using a 1.8 μm femtosecond fiber laser system. Biomedical Optics Express. 2023. 14. 1. 326-334
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Hiromi H Ueda, Yutaro Nagasawa, Aiko Sato, Maki Onda, Hideji Murakoshi. Chronic neuronal excitation leads to dual metaplasticity in the signaling for structural long-term potentiation. Cell reports. 2022. 38. 1. 110153-110153
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Akihiro C E Shibata, Hiromi H Ueda, Kei Eto, Maki Onda, Aiko Sato, Tatsuko Ohba, Junichi Nabekura, Hideji Murakoshi. Photoactivatable CaMKII induces synaptic plasticity in single synapses. Nature communications. 2021. 12. 1. 751-751
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Takeshi Shimizu, Hideji Murakoshi, Hidetoshi Matsumoto, Kota Ichino, Atsunori Hattori, Shinya Ueno, Akimasa Ishida, Naoki Tajiri, Hideki Hida. Tension Sensor Based on Fluorescence Resonance Energy Transfer Reveals Fiber Diameter-Dependent Mechanical Factors During Myelination. Frontiers in cellular neuroscience. 2021. 15. 685044-685044
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MISC (19):
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Hiromi H Ueda, Yutaro Nagasawa, Hideji Murakoshi. Imaging intracellular protein interactions/activity in neurons using 2-photon fluorescence lifetime imaging microscopy. Neuroscience research. 2021
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Hideji Murakoshi. Optogenetic Imaging of Protein Activity Using Two-Photon Fluorescence Lifetime Imaging Microscopy. Advances in experimental medicine and biology. 2021. 1293. 295-308
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Hideji Murakoshi. Minorities and Small Numbers from Molecules to Organisms in Biology. Springer Singapore. 2018
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Murakoshi H. [Optogenetics sheds light on memory research.Development and application of photoactivatable CaMKII inhibitory peptide to the study of synaptic plasticity.]. Clinical calcium. 2018. 28. 3. 414-419
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Hideji Murakoshi, Ryohei Yasuda. Imaging signal transduction in dendrites using genetically encoded biosensors. Dendrites: Development and Disease. 2016. 139-154
more...
Education (1):
- 1999 - 2004 Nagoya University Graduate School of Science Division of Biological Science
Professional career (1):
Work history (5):
- 2011/07 - 現在 National Institute for Physiological Sciences Supportive Center for Brain Research
- 2011/10 - 2015/03 Japan Science and Technology Agency
- 2006/07 - 2011/06 Duke University Medical Center 研究員
- 2005/04 - 2007/11 日本学術振興会 特別研究員PD
- 2004/04 - 2005/03 JST SORST 楠見膜組織能プロジェクト 研究員
Awards (2):
- 2012/03 - 日本生理学会ポスターアワード受賞
- 2011/09 - 日本生物物理学会若手奨励賞受賞
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