Rchr
J-GLOBAL ID:201701013720650326   Update date: Feb. 22, 2024

Kawasoe Yoshitaka

Kawasoe Yoshitaka
Research field  (1): Molecular biology
Research keywords  (6): DNA replication ,  DNA repair ,  Xenopus egg extracts ,  mismatch repair ,  DNA double-strand break ,  PCNA
Research theme for competitive and other funds  (5):
  • 2022 - 2024 相同組換えの正確性制御メカニズムの試験管内再構成による解明
  • 2023 - 2024 光照射による特定反応誘導可能な新規試験管内生命現象解析ツールの構築とその評価
  • 2022 - 2023 試験管内再構成による相同組換え反応正確性制御メカニズムの解明
  • 2019 - 2022 Elucidation of regulations of PCNA dynamics by the mismatch repair system
  • 2017 - 2019 PCNAアンローディングをミスマッチ修復機構が制御するメカニズムの解明
Papers (9):
  • Kensuke Tatsukawa, Reihi Sakamoto, Yoshitaka Kawasoe, Yumiko Kubota, Toshiki Tsurimoto, Tatsuro S Takahashi, Eiji Ohashi. Resection of DNA double-strand breaks activates Mre11-Rad50-Nbs1- and Rad9-Hus1-Rad1-dependent mechanisms that redundantly promote ATR checkpoint activation and end processing in Xenopus egg extracts. Nucleic acids research. 2024
  • Yoshitaka Kawasoe, Sakiko Shimokawa, Peter J. Gillespie, J. Julian Blow, Toshiki Tsurimoto, Tatsuro S. Takahashi. The Atad5 RFC-like complex is the major unloader of proliferating cell nuclear antigen in Xenopusegg extracts. 2023
  • Kensuke Tatsukawa, Reihi Sakamoto, Yoshitaka Kawasoe, Yumiko Kubota, Toshiki Tsurimoto, Tatsuro S. Takahashi, Eiji Ohashi. Unique and shared functions of the Rad9-Hus1-Rad1 and Mre11-Rad50-Nbs1 complexes in ATR checkpoint activation and long-range DNA end resection in Xenopusegg extracts. 2023
  • Ryota Miyashita, Atsuya Nishiyama, Weihua Qin, Yoshie Chiba, Satomi Kori, Norie Kato, Chieko Konishi, Soichiro Kumamoto, Hiroko Kozuka-Hata, Masaaki Oyama, et al. The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5. eLife. 2023. 12
  • Mathew J K Jones, Camille Gelot, Stephanie Munk, Amnon Koren, Yoshitaka Kawasoe, Kelly A George, Ruth E Santos, Jesper V Olsen, Steven A McCarroll, Mark G Frattini, et al. Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication. Molecular cell. 2021. 81. 3. 426-441
more...
Lectures and oral presentations  (17):
  • WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する
    (第27回 DNA複製・組換え・修復ワークショップ 2023)
  • WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する
    (第45回日本分子生物学会年会 2022)
  • 試験管内再構成による抗組換え反応のメカニズムの解析
    (第45回日本分子生物学会年会 2022)
  • WernerヘリカーゼとMutLαエンドヌクレアーゼは一本鎖アニーリングの正確性を制御する
    (第95回日本生化学会大会 2022)
  • Werner helicase and MutLα endonuclease control the fidelity of DNA double strand break repair
    (2021)
more...
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