Ohnishi Takashi

オオニシタカシ | Ohnishi Takashi

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Orthopedics

Research theme for competitive and other funds (5)：

2022 - 2025 椎間板障害に対するexosome を用いた低侵襲治療法の開発
2022 - 2024 椎間板障害に対する exosome を用いた低侵襲治療法の開発
2022 - 2024 椎間板障害に対するexosome を用いた低侵襲治療法の開発
2021 - 2022 外傷や生体力学的負荷により生じる椎間板障害に対するexosome を用いた低侵襲治療法の開発
2019 - 2021 脊椎椎間板変性における炎症性メディエーターの関与と治療

Papers (23)：

Yoko Ishikawa, Satoshi Kanai, Katsuro Ura, Terufumi Kokabu, Katsuhisa Yamada, Yuichiro Abe, Hiroyuki Tachi, Hisataka Suzuki, Takashi Ohnishi, Tsutomu Endo, et al. Development of Notch-Free, Pre-Bent Rod Applicable for Posterior Corrective Surgery of Thoracolumbar/Lumbar Adolescent Idiopathic Scoliosis. Journal of clinical medicine. 2023. 12. 17
Takashi Ohnishi, Kentaro Homan, Akira Fukushima, Daisuke Ukeba, Norimasa Iwasaki, Hideki Sudo. A Review: Methodologies to Promote the Differentiation of Mesenchymal Stem Cells for the Regeneration of Intervertebral Disc Cells Following Intervertebral Disc Degeneration. Cells. 2023. 12. 17. 2161-2161
Takashi Ohnishi, Victoria Tran, Kimheak Sao, Pranay Ramteke, William Querido, Ruteja A. Barve, Koen van de Wetering, Makarand V. Risbud. Loss of function mutation in Ank causes aberrant mineralization and acquisition of osteoblast-like-phenotype by the cells of the intervertebral disc. Cell Death & Disease. 2023. 14. 7. 447-447
Katsuhisa Yamada, Ken Nagahama, Yuichiro Abe, Yoshinori Hyugaji, Daisuke Ukeba, Tsutomu Endo, Takashi Ohnishi, Katsuro Ura, Hideki Sudo, Norimasa Iwasaki, et al. Evaluation of Surgical Indications for Full Endoscopic Discectomy at Lumbosacral Disc Levels Using Three-Dimensional Magnetic Resonance/Computed Tomography Fusion Images Created with Artificial Intelligence. Medicina (Kaunas, Lithuania). 2023. 59. 5
Katsuhisa Yamada, Hideki Sudo, Yuichiro Abe, Terufumi Kokabu, Hiroyuki Tachi, Tsutomu Endo, Takashi Ohnishi, Daisuke Ukeba, Katsuro Ura, Masahiko Takahata, et al. Influence of Lateral Translation of Lowest Instrumented Vertebra on L4 Tilt and Coronal Balance for Thoracolumbar and Lumbar Curves in Adolescent Idiopathic Scoliosis. Journal of Clinical Medicine. 2023. 12. 4. 1389-1389

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MISC (124)：

大西貴士. 【ナースのギモン大解決!なるほどナットク!見てわかる!整形外科のあやふや知識】脊椎(Q8) 腰椎椎体間固定術(PLIF・TLIF・XLIF・OLIF・ALIF)はどう違う?. 整形外科看護. 2024. 29. 1. 35-37
大西貴士, 中下並人, 山田勝久, 須藤英毅, 岩崎倫政. 腰椎後方除圧術における棘上棘間靱帯・棘突起温存は,術後の二次性椎間板変性の進行を抑制する. 東日本整形災害外科学会雑誌. 2023. 35. 3. 292-292
山田勝久, 長濱賢, 安倍雄一郎, 日向寺義則, 筌場大介, 遠藤努, 大西貴士, 浦勝郎, 高畑雅彦, 須藤英毅, et al. AI技術により作成した3D腰神経MRI像を用いたL5/Sレベルの全内視鏡下椎間板ヘルニア摘出術シミュレーションの有用性. 日本整形外科学会雑誌. 2023. 97. 8. S1698-S1698
大西貴士, 宝満健太郎, 須藤英毅, 山田勝久, 岩崎倫政. 骨髄由来間葉系細胞移植による再生医療を背景とした椎間板再生に有効な核酸ターゲットの探索. 日本整形外科学会雑誌. 2023. 97. 8. S1858-S1858
石川蓉子, 小甲晃史, 山田勝久, 安倍雄一郎, 舘弘之, 鈴木久崇, 大西貴士, 遠藤努, 岩崎倫政, 須藤英毅. 三次元デプスセンサーと人工知能を用いた側彎角の自動予測着衣の有無による精度検証. 日本整形外科学会雑誌. 2023. 97. 8. S1914-S1914

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Professional career (1)：

医学博士 (北海道大学大学院医学研究科)

Work history (4)：

2024/04 - 現在 Hokkaido University Hospital Department of Orthopaedic Surgery Assisstant professor
2022/06 - 2024/03 Faculty of Medicine and Graduate School of Medicine, Hokkaido University Department of Orthopaedic Surgery Assistant Professor
2021/11 - 2022/05 Hokkaido University Hospital Department of Orthopaedic Surgery
2019/10 - 2021/09 Thomas Jefferson University Department of Orthopaedic Research Visiting Scholar

Awards (4)：

2023/05 - Korean Society of Spine Surgery Best Paper Award Loss of Function in Ank Gene Causes Aberrant Mineralization and Acquisition of Osteoblast-like-phenotype in the Cells of Annulus Fibrosus
2022/04 - English Presentation Session Silver Award Loss of function in Ank gene causes aberrant mineralization and acquisition of osteoblast-like-phenotype in the cells of annulus fibrosus
2020 - 32th JSSR Basic Award Caspase-3 knockout inhibits intervertebral disc degeneration related to injury but accelerates degeneration related to aging.
2018/03 - 2018 ORS/OREF Travel Award in Orthopaedic Research Translation

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