Yukiko Matsuo

Research field (1)： Environmental and pharmaceutical development resources

Research keywords (6)： metabolic syndrome , kampo , sesquiterpene , steroidal glycoside , natural products , antitumor

Research theme for competitive and other funds (7)：

2023 - 2026 Search for new seeds of anti-cancer agents targeting PARP from natural products
2020 - 2023 IDO-1を分子標的とした天然物由来の難治がん治療薬のシーズ探索とその併用効果
2018 - 2021 Search for seeds of anti-lifestyle-related disease drugs and antineoplastic drugs from invasive alien species
2017 - 2021 Search for new natural products with anticancer potential in targeting with AMPK, and their combination effects with metformin
2016 - 2019 Research on steroidal glycosides with anti-metabolic syndrome activity in vivo

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Papers (37)：

Yukiko Matsuo, Takuya Fujii, Hironao Kato, Kazuki Tomizawa, Haruhiko Fukaya, Katsunori Miyake, Minpei Kuroda, Yoshihiro Mimaki. Lanceolanone A, a new biflavanone, and a chalcone glucoside from the flower heads of Coreopsis lanceolata and their aldose reductase inhibitory activity and AMPK activation. Journal of natural medicines. 2022
Naoko Kuwabara, Yukiko Matsuo, Tsuyoshi Ueki, Yuki Nakamura, Nanami Kase, Taisuke, Okayasu, Yoshihiro Mimaki, Eiichi Tachikawa, Shinji Sato, et al. Inhibitory Effect of Rhei Rhizoma Constituents on the Cortisol Production in ACTH-Stimulated Bovine Adrenal Fasciculata Cells. Traditional Medicine. 2022. 3. 2. 1-7
Yukiko Matsuo, Hiroko Tsuchihashi, Kazuhiro Takatori, Haruhiko Fukaya, Minpei Kuroda, Yoshihiro Mimaki. Cytotoxic triterpene and steroidal glycosides from the seeds of Digitalis purpurea and the synergistic cytotoxicity of steroidal glycosides and etoposide in SBC-3 cells. Bioorganic chemistry. 2022. 122. 105697-105697
冨澤一樹, 加藤宏直, 藤井拓也, 松尾侑希子, 深谷晴彦, 三宅克典, 黒田明平, 三巻祥浩. 特定外来植物からの医薬品シーズの探索研究オオキンケイギク頭花の化学成分とAMPK活性化. 日本薬学会年会要旨集. 2022. 142年会. 27PO1-18S
Kazuhiro Takatori, Minpei Kuroda, Masaki Mishima, Yukiko Matsuo, Yoshihiro Mimaki. Digipregnosides A-C, three novel rearranged 11,12-secopregnane glycosides, and digipregnosides D and E, 12,20-epoxypregnane glycosides from the seeds of Digitalis purpurea. Tetrahedron Letters. 2021. 70. 153020-153020

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MISC (81)：

松尾侑希子, 井口巴樹, 黒田明平, 三宅克典, 加藤宏直, 木村優花, 三巻祥浩. Triterpene Glycosides from the Underground Parts of Alternanthera philoxeroides Designated as an Invasive Alien Species and Their Cytotoxicity. 生薬学雑誌. 2024. 78. 1
羽賀淳貴, 横須賀章人, 赤岩玲奈, 松尾侑希子, 三宅克典, 三巻祥浩. ユリ科植物の化学成分(93)オウゴンオニユリLilium lancifolium var.flaviflorumの化学成分(2). 日本薬学会関東支部大会講演要旨集(CD-ROM). 2023. 67th
菊地美静, 松尾侑希子, 川原有菜, 赤岩玲奈, 柳岡美紅, 吉田拓真, 稲葉二朗, 井口巴樹, 中南秀将, 三巻祥浩. トリプシン阻害活性を示す漢方エキス製剤のスクリーニング(4). 和漢医薬学会学術大会要旨集. 2023. 40th
諸喜田すず, 田中三鈴, 松尾侑希子, 三宅克典, 三巻祥浩. トベラ科トベラPittosporum tobira葉の化学成分とIDO1阻害活性. 日本薬学会関東支部大会講演要旨集(CD-ROM). 2022. 66th
山寺祐輔, 松尾侑希子, 三宅克典, 三巻祥浩. ユリ科植物の化学成分(92)オウゴンオニユリLilium lancifolium var.flaviflorumの化学成分について(1). 日本薬学会関東支部大会講演要旨集. 2021. 65th (CD-ROM)

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Patents (2)：

美白剤、美白用化粧料及び美白剤の製造方法
美白剤、美白用化粧料及び美白剤の製造方法

Lectures and oral presentations (2)：

がん治療薬のシーズ化合物の探索研究~ステロイド系化合物を中心に~
(第39回和漢医薬学会学術大会 2022)
生物活性を指標としたがんと生活習慣病の治療薬のシーズ探索研究
(第65回日本薬学会関東支部会 2021)

Professional career (1)：

薬学 (東京薬科大学)

Awards (1)：

2021/09 - 日本生薬学会学術奨励賞天然物を由来とするステロイド系化合物からの新規抗がん剤シーズの探索研究

Association Membership(s) (4)：

MEDICAL AND PHARMACEUTICAL SOCIETY FOR WAKAN-YAKU , THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER , THE JAPANESE SOCIETY OF PHARMACOGNOSY , THE PHARMACEUTICAL SOCIETY OF JAPAN

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