Takashima Shigeo

タカシマシゲオ | Takashima Shigeo

Affiliation and department：
Job title： Associate Professor
Other affiliations (3)：

Gifu University Division of Genomics Research, Life Science Research Cetner Associate Professor
Gifu University Center for One Medicine Innovative Translational Research (COMIT) Associate Professor
Gifu University United Graduate School of Drug Discovery and Medical Information Sciences Associate Professor

Homepage URL (2)： http://stakashimaj.blogspot.jp/ , http://stakashima.blogspot.jp/

Research field (1)： Developmental biology

Research keywords (6)： Fatty acid metabolism , Very Long Chain Fatty Acid , Inherited Metabolic Diseases , Peroxisomal Disease , X-linked adrenoleukodystrophy (X-ALD) , Developmental genetics

Research theme for competitive and other funds (9)：

2021 - 2025 Studies on the interaction between changes of molecules in exosomes and the development of enzootic bovine leukosis
2019 - 2024 ゴルジ体ストレスシグナルに着目した新たな老年病発症メカニズムの解析
2020 - 2023 Identification of the pathological metabolites of peroxisome biogenesis disorder using disease models
2016 - 2019 疾患モデルフィッシュを用いたペルオキシソーム病発病因子の特定と治療法の開発
2015 - 2018 Research on elucidation of pathology and drug discovery in peroxisomal diseases using stem cells and diseased model organisms

Show all

Papers (74)：

Aimi Fuyuki, Md Shahriar Hasan Sohel, Takeshi Homma, Kai Kitamura, Shigeo Takashima, Sawa Onouchi, Shouichiro Saito. Selective prosaposin expression in Langerhans islets of the mouse pancreas. Tissue & cell. 2024. 88. 102367-102367
Rei Funahashi, Fumiaki Matsuura, Masayuki Ninomiya, Sayo Okabe, Shigeo Takashima, Kaori Tanaka, Atsuyoshi Nishina, Mamoru Koketsu. Hybrid pharmacophore design and synthesis of donepezil-inspired aurone derivative salts as multifunctional acetylcholinesterase inhibitors. Bioorganic chemistry. 2024. 145. 107229-107229
Md Matiur Rahman, Hinata Ishikawa, Marika Yamauchi, Shigeo Takashima, Yuji O Kamatari, Kaori Shimizu, Ayaka Okada, Yasuo Inoshima. Characterization of mRNA Signature in Milk Small Extracellular Vesicles from Cattle Infected with Bovine Leukemia Virus. Pathogens (Basel, Switzerland). 2023. 12. 10. 1239-1239
Teiko Komori Nomura, Satoshi Endo, Takuma Kuwano, Kazuya Fukasawa, Shigeo Takashima, Tomoki Todo, Kyoji Furuta, Takuhei Yamamoto, Eiichi Hinoi, Hiroko Koyama, et al. ARL-17477 is a dual inhibitor of NOS1 and the autophagic-lysosomal system that prevents tumor growth in vitro and in vivo. Scientific reports. 2023. 13. 1. 10757-10757
Kyoka Kawaguchi, Miyu Watanabe, Saho Furukawa, Kenichi Koga, Hiromitsu Kanamori, Mitsushi J Ikemoto, Shigeo Takashima, Miwa Maeda, Kentaro Oh-Hashi, Yoko Hirata, et al. Intermittent inhibition of FYVE finger-containing phosphoinositide kinase induces melanosome degradation in B16F10 melanoma cells. Molecular biology reports. 2023. 50. 7. 5917-5930

ｍore...

MISC (30)：

川合裕規, 久保田一生, 高島茂雄, 大西秀典, 下澤伸行. 副腎白質ジストロフィーにおける病型と血中極長鎖脂肪酸値の相関についての検討. 日本先天代謝異常学会雑誌. 2022. 38. 203-203
下澤伸行, 高島茂雄, 川合裕規, 笹井英雄, 久保田一生, 中田智彦, 村松秀城, 夏目淳, 伊藤哲哉, 大西秀典. 難治性小児神経疾患の新生児スクリーニング国内新規導入の現状と課題副腎白質ジストロフィー. 脳と発達. 2022. 54. Suppl. S120-S120
川合裕規, 久保田一生, 高島茂雄, 大西秀典, 下澤伸行. 副腎白質ジストロフィーの重症度と血中極長鎖脂肪酸値の相関についての再検討. 脳と発達. 2022. 54. Suppl. S249-S249
久保田一生, 高島茂雄, 川合裕規, 大西秀典, 鈴木康之, 下澤伸行. 日本人二頭酵素欠損症患者におけるてんかん症状と遺伝学的、生化学的検討. 脳と発達. 2022. 54. Suppl. S336-S336
下澤伸行, 高島茂雄, 川合裕規, 笹井英雄, 久保田一生, 松本英樹, 堀友博, 折居建治, 鈴木康之, 中田智彦, et al. 拡大新生児マススクリーニングの展望と課題:新規候補疾患のエビデンス副腎白質ジストロフィー新生児マススクリーニングの現状と課題. 日本小児科学会雑誌. 2022. 126. 2. 220-220

ｍore...

Books (2)：

Experimental Medicine, Special number Vol. 28 No. 7
Yodosha Co., Ltd. 2010 ISBN:9784758103060
Cell Technology Vol. 27 No. 11
Shujunsha Co., Ltd. 2008 ISBN:9784879624901

Lectures and oral presentations (4)：

質量分析を応用したペルオキシソーム病代謝解析法の開発
(第42回日本医用マススペクトル学会年会シンポジウム質量分析の代謝異常症への応用 2017)
遺伝病にどう向き合うか -幹細胞移植と遺伝子治療-
(岐阜大学公開講座生命科学への扉 ~研究がもたらすもの~ 2014)
先端生命科学の2大革命-iPS細胞と次世代遺伝子診断-
(岐阜大学公開講座生命科学への扉 ~研究がもたらすもの~ 2013)
メダカに学ぶ私たちのからだ
(岐阜大学公開講座 ~先端科学を知ろう~ 2012)

Professional career (1)：

博士(理学) (山口大学)

Association Membership(s) (3)：

Japanese Society of Developmental Biologists , The Molecular Biology Society of Japan , Japanese Society for Inherited Metabolic Diseases

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page