Yasunari Kanda

カンダヤスナリ | Yasunari Kanda

Homepage URL (1)： http://www.nihs.go.jp/phar/phar-j.html

Research field (1)： Pharmacology

Research keywords (8)： Lipid , Signal transducstion , Receptor , Pharmacology , Safety assessment , Cancer stem cells , Stem cells , iPS cells

Research theme for competitive and other funds (16)：

2021 - 2025 超瞬間レーザー解凍による次世代細胞凍結保存技術の確立とバイオバンキングへの展開
2021 - 2024 Development of mature iPSC cardiomyocytes toward drug development
2021 - 2024 ヒトiPS細胞技術を用いた新たな心毒性評価法の開発と国際標準化
2020 - 2023 ALS患者iPS細胞由来ミクログリアを用いた炎症反応模倣BBB評価系の構築
2019 - 2023 A multidisciplinary approaches for drug-induced arrhythmia using human iPS cells

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Papers (163)：

Akiyuki Nishimura, Liuchenzi Zhou, Yuri Kato, Xinya Mi, Tomoya Ito, Yuko Ibuki, Yasunari Kanda, Motohiro Nishida. Supersulfide prevents cigarette smoke extract-induced mitochondria hyperfission and cardiomyocyte early senescence by inhibiting Drp1-filamin complex formation. Journal of pharmacological sciences. 2024. 154. 2. 127-135
Yasunari Kanda, Junko Kurokawa. [Comprehensive Assessment of Cardiovascular Toxicity~From Basic to Clinic~]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2024. 144. 3. 249-250
Xiaokang Tang, Akiyuki Nishimura, Kohei Ariyoshi, Kazuhiro Nishiyama, Yuri Kato, Elena A Vasileva, Natalia P Mishchenko, Sergey A Fedoreyev, Valentin A Stonik, Hyoung-Kyu Kim, et al. Echinochrome Prevents Sulfide Catabolism-Associated Chronic Heart Failure after Myocardial Infarction in Mice. Marine drugs. 2023. 21. 1
Yosuke Uchiyama, Daiju Yamazaki, Naoki Kobayashi, Yasunari Kanda, Yoshiko Sugita-Konishi. Electrophysiological Effect of Citreoviridin on Human InducedPluripotent Stem Cell-derived Cardiomyocytes. Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi). 2022. 63. 6. 210-217
Yuri Kato, Kazuhiro Nishiyama, Jae Man Lee, Yuko Ibuki, Yumiko Imai, Takamasa Noda, Noriho Kamiya, Takahiro Kusakabe, Yasunari Kanda, Motohiro Nishida. TRPC3-Nox2 Protein Complex Formation Increases the Risk of SARS-CoV-2 Spike Protein-Induced Cardiomyocyte Dysfunction through ACE2 Upregulation. International journal of molecular sciences. 2022. 24. 1

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MISC (53)：

田京茉実, 田京茉実, 三澤隆史, 平田尚也, 諫田泰成, 石田寛明, 山本恵子, 出水庸介, 出水庸介. Development of helical peptides containing non-proteinogenic amino acids inhibiting VDR-mediated transcription. 日本薬学会年会要旨集(Web). 2022. 142nd
津田萌菜, 津田萌菜, 正田卓司, 平田尚也, 諫田泰成, 井上英史, 出水庸介, 出水庸介. Development of Selective Estrogen Receptor βDown-regulators Containing a Long Alkyl Chains. 日本薬学会年会要旨集(Web). 2022. 142nd
津田萌菜, 津田萌菜, 正田卓司, 平田尚也, 諫田泰成, 井上英史, 出水庸介. 長鎖アルキル基を有する選択的エストロゲン受容体分解誘導剤の開発. 日本薬学会関東支部大会講演要旨集. 2021. 65th (CD-ROM)
中瀬古寛子, 諫田泰成, 長澤美帆子, 内藤篤彦, 関野祐子, 杉山篤. ヒト人工多能性幹細胞由来心筋細胞シートの細胞外電位持続時間の補正式の開発. 応用薬理. 2018. 94. 5-6. 111-111
三澤隆史, 諫田泰成, 出水庸介. 多様な官能基修飾を志向したヘリカルテンプレートペプチドの開発. 日本薬学会年会要旨集(CD-ROM). 2018. 138th. ROMBUNNO.27PA-am080

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Professional career (1)：

博士(薬学) (東京大学)

Work history (2)：

2017/04 - 現在国立医薬品食品衛生研究所薬理部部長
2008/04 - 2017/03 国立医薬品食品衛生研究所薬理部第二室長

Committee career (4)：

2020/04 - 現在日本薬理学会理事
2019/04 - 現在日本動物実験代替法学会理事
2017/04 - 現在 DIA cardiac safety workshop プログラム委員
2016/04 - 現在国際安全性薬理学会プログラム委員

Association Membership(s) (13)：

International Society for Stem Cell Research , Safety Pharmacology Society , Japanese Safety Pharmacology Society , THE JAPAN NEUROSCIENCE SOCIETY , SOCIETY FOR REGULATORY SCIENCE OF MEDICAL PRODUCTS , JAPANESE SOCIETY FOR ALTERNATIVES TO ANIMAL EXPERIMENTS , THE JAPANESE SOCIETY FOR NEUROCHEMISTRY , THE JAPANESE BIOCHEMICAL SOCIETY , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE SOCIETY FOR REGENERATIVE MEDICINE , THE JAPANESE SOCIETY OF TOXICOLOGY , THE PHARMACEUTICAL SOCIETY OF JAPAN , THE JAPANESE PHARMACOLOGICAL SOCIETY

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