Otani Junji

オオタニジュンジ | Otani Junji

Affiliation and department：
Job title： Assistant Professor

Research field (2)： Structural biochemistry , Molecular biology

Research theme for competitive and other funds (5)：

2020 - 2023 配列特異的翻訳抑制蛋白質によるHippo-YAP経路の制御
2018 - 2020 Elucidation of molecular mechanisms of tumor initiation and progression by ribosomal stresses
2016 - 2019 Role of YAP1/TAZ in cell competition
2016 - 2018 Biochemical study of a splicing factor Sde2
2011 - 2012 テロメア特異的蛋白質複合体シェルタリンによるテロメラーゼの制御機構解明

Papers (25)：

Tomohiko Maehama, Miki Nishio, Junji Otani, Tak Wah Mak, Akira Suzuki. Nucleolar stress: Molecular mechanisms and related human diseases. Cancer science. 2023
Yusuke Shiraishi, Tomohiko Maehama, Miki Nishio, Junji Otani, Hiroki Hikasa, Tak Wah Mak, Takehiko Sasaki, Teruki Honma, Yasumitsu Kondoh, Hiroyuki Osada, et al. N-(3,4-dimethoxyphenethyl)-6-methyl-2,3,4,9-tetrahydro-1H-carbazol-1-amine inhibits bladder cancer progression by suppressing YAP1/TAZ. GENES TO CELLS. 2022. 27. 10. 602-612
Yuntao Dai, Tetsuya Kawaguchi, Miki Nishio, Junji Otani, Hironori Tashiro, Yoshito Terai, Ryohei Sasaki, Tomohiko Maehama, Akira Suzuki. The TIGD5 gene located in 8q24 and frequently amplified in ovarian cancers is a tumor suppressor. GENES TO CELLS. 2022
Hirotoshi Soyama, Miki Nishio, Junji Otani, Toshiko Sakuma, Shintaro Takao, Shigeo Hara, Takaaki Masuda, Koshi Mimori, Shinya Toyokuni, John P. Lydon, et al. Hippo-TAZ signaling is the master regulator of the onset of triple-negative basal-like breast cancers. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2022. 119. 29
西尾美希, 前濱朝彦, 大谷淳二, 曽山弘敏, 鈴木聡. 動物モデルによる先端がん研究 Hippoシグナルによるがんの発症進展制御. 日本生化学会大会プログラム・講演要旨集. 2021. 94回. [1S04a-01]

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MISC (3)：

Education (1)：

Professional career (2)：

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