Rchr
J-GLOBAL ID:201701018533416257
Update date: May. 08, 2024
Tsukamoto Takashi
ツカモト タカシ | Tsukamoto Takashi
Affiliation and department:
Job title:
Assostant Professor
Homepage URL (1):
https://altair.sci.hokudai.ac.jp/infana/
Research field (5):
Biogeoscience
, Ecology and environmental science
, Biophysics
, Molecular biochemistry
, Biophysics
Research keywords (6):
過渡吸収分光
, 膜輸送
, Membrane Proteins
, Retinal Proteins
, Photobiology
, Biophysics
Research theme for competitive and other funds (14):
- 2023 - 2026 アニオンチャネルロドプシンの動的なイオン選択性メカニズムの解明
- 2022 - 2025 過渡現象解析で追求する膜輸送タンパク質の多段階構造変化と輸送素過程の連関
- 2022 - 2025 全長型アニオンチャネルロドプシンのイオン輸送機能:C末端ドメインの役割について
- 2022 - 2023 天然全長型アニオンチャネルロドプシンの見過ごされてきた分子機能
- 2021 - 2022 トライアル研究支援制度
- 2019 - 2021 生体分子中の窒素の特性を、中性子回折と計算化学により解明する
- 2018 - 2020 イオン輸送型ロドプシンのアミノ酸変異による輸送方式の変換とその分子機構の解明
- 2015 - 2018 Investigation, modification and utilization of the retinal proteins
- 2017 - 2018 光駆動細胞内向きプロトン輸送タンパク質の分子機構の解明と応用技術
- 2015 - 2018 高度好熱菌ロドプシンにおける構造安定性の追求(研究課題番号:15K18519)
- 2015 - 2017 Time-resolved infrared spectroscopy of the thermophilic rhodopsin under various pressures and temperatures
- 2016 - 2017 カロテノイド結合型ロドプシンの2光子吸収による活性化の可能性調査
- 2016 - 2016 時間分解赤外分光法によるレチナールタンパク質の構造ダイナミクスの解析
- 2015 - 2016 時間分解赤外分光法によるレチナールタンパク質の構造ダイナミクスの解析
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Papers (37):
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Yukino Sato, Tsubasa Hashimoto, Koji Kato, Akiko Okamura, Kaito Hasegawa, Tsukasa Shinone, Yoshikazu Tanaka, Yoshiki Tanaka, Tomoya Tsukazaki, Takashi Tsukamoto, et al. Multistep conformational changes leading to the gate opening of light-driven sodium pump rhodopsin. The Journal of biological chemistry. 2023. 105393-105393
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Yuya Ohki, Tsukasa Shinone, Sayo Inoko, Miu Sudo, Makoto Demura, Takashi Kikukawa, Takashi Tsukamoto. The preferential transport of NO3- by full-length Guillardia theta anion channelrhodopsin 1 is enhanced by its extended cytoplasmic domain. The Journal of biological chemistry. 2023. 105305-105305
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Masaiku Ohya, Takashi Kikukawa, Junpei Matsuo, Takashi Tsukamoto, Ryota Nagaura, Tomotsumi Fujisawa, Masashi Unno. Structure and Heterogeneity of Retinal Chromophore in Chloride Pump Rhodopsins Revealed by Raman Optical Activity. The journal of physical chemistry. B. 2023
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Kunisato Kuroi, Takashi Tsukamoto, Naoya Honda, Yuki Sudo, Yuji Furutani. Concerted primary proton transfer reactions in a thermophilic rhodopsin studied by time-resolved infrared spectroscopy at high temperature. Biochimica et biophysica acta. Bioenergetics. 2023. 1864. 3. 148980-148980
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Yuhei Doi, Jo Watanabe, Ryota Nii, Takashi Tsukamoto, Makoto Demura, Yuki Sudo, Takashi Kikukawa. Mutations conferring SO42- pumping ability on the cyanobacterial anion pump rhodopsin and the resultant unique features of the mutant. Scientific reports. 2022. 12. 1. 16422-16422
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MISC (14):
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塚本卓, 出村誠. 光で働く微生物のロドプシン-どのように?なんのために?を紐解いてきた50年. 化学. 2021. 76. 4
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宋 子豪, 包 克非, 北田 直也, 清水 由宇, 菊池 摩仁, 熊木 康裕, 大西 裕季, 塚本 卓, 菊川 峰志, 出村 誠, et al. ヒト便試料の保存条件とメタボローム変動のNMR解析(Impact of sample storage conditions on NMR-based human fecal metabolomics). 腸内細菌学雑誌. 2020. 34. 2. 148-148
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GU Hao, 加藤貴純, 石田博昭, 熊木康裕, 塚本卓, 塚本卓, 菊川峰志, 菊川峰志, 出村誠, 出村誠, et al. Overexpression of stable isotope-labeled cecropin P1 by using calmodulin-fusion protein system and NMR researches. Abstracts. Annual Meeting of the NMR Society of Japan. 2020. 59th
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水谷健二, 橋本直記, 塚本卓, 須藤雄気, 村田武士. 微生物型ロドプシンTRのX線結晶構造解析. KEK Progress Report (Web). 2017. 2016-8. ROMBUNNO.242 (WEB ONLY)
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Sayaka Nemoto, Satoshi Yasuda, Takashi Tsukamoto, Yuki Sudo, Masahiro Kinoshita, Takeshi Murata. Identification of thermostabilizing mutations for the Thermophilic Rhodopsin based on statistical thermodynamics. 第54回 日本生物物理学会年会 つくば国際会議場、2016年11月25-27日. 2016
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Lectures and oral presentations (49):
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Anion Concentration Dependency on the Photocycle of PsuACR1: Implications for the Impairment of its Fast Channel Function.
(18th International Conference on Retinal Proteins 2018)
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Substrate anion concentration significantly affects the fast channel function of Proteomonas sulcata anion channelrhodopsin-1
(2018)
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Photochemical Properties of Microbial Rhodopsin Pumps and Channels
(APSBMS 2018 Annual Meeting 2018)
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塩濃度に依存したアニオンチャネルロドプシンの光化学的性質の変化
(日本生物物理学会北海道支部例会 2018)
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Light-driven Cl- transport mechanism of Nonlabens marinus rhodopsin-3 studied by static and time-resolved spectroscopy
(日本生物物理学会第55回年会 2017)
more...
Education (3):
- 2010 - 2013 Hokkaido University Graduate School of Life Science
- 2008 - 2010 Hokkaido University Graduate School of Life Science
- 2004 - 2008 Hokkaido University School of Science Biological Sciences (Macromolecular Functions)
Professional career (1):
- Ph.D. (Hokkaido University)
Work history (5):
- 2017/04 - 現在 Hokkaido University Faculty of Advanced Life Science Assistant professor
- 2014/07 - 2017/03 Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences Assistant professor
- 2014/04 - 2014/06 Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences
- 2013/04 - 2014/03 Nagoya University Division of Biological Science, Graduate School of Science
- 2010/09 - 2010/11 National Institute for Materials Science
Committee career (6):
Awards (1):
- 2005/10 - Hokkaido University Nitobe Prize
Association Membership(s) (2):
Japanese Society of Microbial Ecology
, THE BIOPHYSICAL SOCIETY OF JAPAN
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