Rchr
J-GLOBAL ID：201701018888365840
Update date: Nov. 13, 2024
Kosuke Nakashima
ナカシマ コウスケ | Kosuke Nakashima
Affiliation and department：
Research field (1)：
Pharmaceuticals - chemistry and drug development
Research keywords (3)：
Synthetic Organic Chemistry
, asymmetric reaction
, organocatalyst
Research theme for competitive and other funds (3)：
- 2024 - 2025 Development and application of stimulus-responsive molecules for deep biological imaging
- 2015 - 2017 Research and development of organocatalyst as an artificial acylating enzyme
- 2017 - The development of the Photoswitchable Organic Catalyst
Papers (53)：
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Yasuyuki Matsushima, Yoshiyuki Iijima, Chinatsu Tanabe, Kosuke Nakashima, Shin-ichi Hirashima, Tsuyoshi Miura. Organocatalyzed Asymmetric Conjugate Addition of Cyclic β-Keto Esters to (E)-β-Nitroacrylate Derivatives. Chemistry - An Asian Journal. 2024
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Kosuke Nakashima, Dancho Yordanov, Yasuyuki Matsushima, Shin-ichi Hirashima, Tsuyoshi Miura, Anton Georgiev. Rearrangement of C2-Spirooxindoles: Conversion to the 2-Hydroxyhemi-Indigo and Chromenoindole. The Journal of Organic Chemistry. 2024
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Yuta Iino, Yasuyuki Matsushima, Kosuke Nakashima, Shin-ichi Hirashima, Tsuyoshi Miura. Organocatalyzed Synthesis of γ-Alkenyl Butenolides via Asymmetric Direct Vinylogous Conjugate Addition-Elimination of Substituted Furanone Derivatives to β-Phenylsulfonylenones. The Journal of Organic Chemistry. 2024. 89. 16. 11789-11795
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Ryo Tsuyusaki, Kosuke Nakashima, Yasuyuki Matsushima, Shin-ichi Hirashima, Tsuyoshi Miura. Organocatalyzed Asymmetric Cascade Michael/Michael Reaction of α-Alkylidene Succinimides with a 2-(Trifluoromethylmethylene)indane-1,3-dione. European Journal of Organic Chemistry. 2024. e202400713
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Eiki Hirota, Shin-Ichi Hirashima, Ryuki Morita, Junya Takase, Yasuyuki Matsushima, Kosuke Nakashima, Hiroshi Akutsu, Tsuyoshi Miura. Regioselective One-Pot Synthesis of Vicinal Bisphosphine Derivatives from Nitroalkenes by Hydrophosphinylation/Elimination/Hydrophosphinylation. Organic letters. 2024. 26. 9. 1797-1802
ｍore...
Lectures and oral presentations (25)：
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有機分子触媒を用いたCF3 基含有スピロインダン-1,3-ジオン誘導体の不斉合成
(第68回 日本薬学会 関東支部大会 2024)
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有機分子触媒を用いたβ-ニトロアクリレートに対するβ-ケトエステルの不斉共役付加反応
(第68回 日本薬学会関東支部大会 2024)
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チオウレア型有機分子触媒を用いたフラン誘導体の位置選択的不斉反応
(第68回 日本薬学会 関東支部大会 2024)
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不斉共役付加反応を利用した2-アザビシクロ[3.3.0]オクタン誘導体の合成
(第49回 反応と合成の進歩シンポジウム)
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第二級ホスフィンスルフィドを用いた有機強塩基触媒による不斉プロトン化反応の開発
(第49回反応と合成の進歩シンポジウム)
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Education (2)：
- 2010 - 2012 Gifu Pharmaceutical University Graduate School Department of Pharmaceutical Science Master's Program
- 2006 - 2010 Gifu Pharmaceutical University Faculty of Pharmaceutical Science Faculty of Pharmaceutial Science
Professional career (1)：
Work history (5)：
- 2022/04 - 現在 東京薬科大学 薬学部 医療薬物薬学科 薬化学教室 講師
- 2017/04 - 2022/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy Assistant Professor
- 2018/05 - 2019/11 Humboldt-Universität zu Berlin Department of Chemistry & IRIS Adlershof Postdoctoral researcher
- 2013/07 - 2017/03 Tokyo University of Pharmacy and Life Sciences School of Pharmacy School of Pharmacy assistant researcher
- 2012/04 - 2013/06 KATAYAMA SEIYAKUSHO Research and deveplopment division researcher
Association Membership(s) (1)：
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