Rchr
J-GLOBAL ID:201701020655740084
Update date: Sep. 24, 2024
VAVRICKA JR CHRISTOPHER JOHN
VAVRICKA JR CHRISTOPHER JOHN
Affiliation and department:
Job title:
Associate Professor
Research field (4):
Functional biochemistry
, Bioorganic chemistry
, Applied biochemistry
, Applied biofunctional and bioprocess engineering
Research theme for competitive and other funds (2):
- 2018 - 2021 Development of sulfo-sialic acids into next-generation antimicrobial agents
- 2018 - 2018 Development sulfosialic acids as irreversible inhibitors of influenaza neuraminidase
Papers (57):
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Musashi Takenaka, Kouhei Kamasaka, Kim Daryong, Keiko Tsuchikane, Seiha Miyazawa, Saeko Fujihana, Yoshimi Hori, Christopher J Vavricka, Akira Hosoyama, Hiroko Kawasaki, et al. Integrated pathway mining and selection of an artificial CYP79-mediated bypass to improve benzylisoquinoline alkaloid biosynthesis. Microbial cell factories. 2024. 23. 1. 178-178
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Shunki Katayama, Mitsuki Nishimoto, Tatsuya Ura, Taiki Ishimoto, Kousuke Ida, Yuki Sato, Christopher J. Vavricka, Minoru Izumi, Hiromasa Kiyota. Synthesis of the C/D/E-ring core compound of maoecrystal V. Synthetic Communications. 2023. 53. 10. 708-712
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Musashi Takekana, Takanobu Yoshida, Erika Yoshida, Sumika Ono, Shinnosuke Horie, Christopher J. Vavricka, Moe Hiratani, Kenji Tsuge, Jun Ishii, Yoshihiro Hayakawa, et al. Online SFE-SFC-MS/MS colony screening: A high-throughput approach for optimizing (-)-limonene production. Journal of Chromatography B. 2023. 1215. 123588-123588
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Kenya Tanaka, Tomokazu Shirai, Christopher J Vavricka, Mami Matsuda, Akihiko Kondo, Tomohisa Hasunuma. Dark accumulation of downstream glycolytic intermediates initiates robust photosynthesis in cyanobacteria. Plant Physiology. 2022
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Varada Jagadeesh, Takanobu Yoshida, Misugi Uraji, Nobuyuki Okahashi, Fumio Matsuda, Christopher J. Vavricka, Kenji Tsuge, Akihiko Kondo. Simple and Rapid Non-ribosomal Peptide Synthetase Gene Assembly Using the SEAM-OGAB Method. ACS Synthetic Biology. 2022
more...
MISC (5):
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工藤恒, VAVRICKA Christopher J., 伏見圭司, 蓮沼誠久, 近藤昭彦. Development of aldehyde-deformylating oxygenase with substrate specificificity toward various carbon chain length aldehydes. 日本生物工学会大会講演要旨集. 2022. 74th
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伏見圭司, 秀瀬涼太, 秀瀬涼太, VAVRICKA Christopher J., 工藤恒, 蓮沼誠久, 蓮沼誠久, 近藤昭彦, 近藤昭彦. Development of alpha-keto acid decarboxylase for tailor-made bio-production. 日本生物工学会大会講演要旨集. 2022. 74th
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蓮沼 誠久, Christopher John Vavricka Jr., 荒木通啓. 新たに設計した代謝経路を用いた大腸菌によるアルカロイド高生産. バイオサイエンスとインダストリー. 2020. 78. 1. 32-33
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清田洋正, C. J. Vavricka. シアリダーゼ阻害剤・抗インフルエンザ薬の創出 - スルホシアル酸の展開. 化学. 2018. 73. 5. 66-67
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George F. Gao, Christopher J. Vavricka. 2009 Pandemic Influenza Virus: What Special for its HA and NA?. ANTIVIRAL RESEARCH. 2011. 90. 2. A26-A26
Patents (2):
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ベンジルイソキノリンアルカロイド(BIA)産生用の組換え宿主細胞及びベンジルイソキノリンアルカロイド(BIA)の新規製造方法
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シアル酸誘導体、その製造方法及びそれを利用したシアリダーゼ阻害剤、抗菌剤、抗ウイルス剤
Lectures and oral presentations (8):
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Genome-scale prediction of gene ontology from yeast knockout MASS fingerprints
(Frontiers in Genome Engineering 2019 2019)
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Application of the design, build, test and learn paradigm to the discovery and engineering of specialized aromatic aldehyde synthases
(The 37th Symposium on Environmental Science of Pesticide 2019)
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Re-design, synthesis, and bio-analysis of sulfosialic acids as covalent inhibitors of neuraminidase
(第61回天然有機化合物討論会 2019)
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A ‘DBTL’ workflow for engineering enzymes in the reticuline pathway
(iBioN 2018 2018)
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Discovery and improvement of covalent influenza neuraminidase inhibitors
(250th American Chemical Society National Meeting & Exposition 2015)
more...
Education (1):
- - 2009 バージニア工科大学 College of Agriculture and Life Sciences修了
Professional career (1):
- Ph.D. (Biochemistry) (バージニア工科大学)
Awards (6):
- 2013 - GENEWIZ Jin Weizhi Publication Award
- 2013 - Chinese Academy of Sciences (CAS), Beijing Institutes of Life Sciences BIOLS Publication Award
- 2013 - Beijing ZEPING Bioscience & Technology Co., Ltd. Publication Award
- 2013 - Beijing Leadman Biochemistry Co., Ltd. Annual Scientific Achievement Award
- 2011 - CAS Key Laboratory of Pathogenic Microbiology and Immunology Qiang Yao Publication Award
- 2011 - CAS Key Laboratory of Pathogenic Microbiology and Immunology Zhou Jiachi Virology Publication Award
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