Ikawa Tomokatsu

イカワトモカツ | Ikawa Tomokatsu

Affiliation and department：
Job title： Professor
Homepage URL (1)： http://www.ribs.tus.ac.jp/index.php/institute/labforres/ikawalab/

Research field (1)： Immunology

Research keywords (7)： Hematopoiesis , Hematopoietic stem cell , Transcriptional regulation , Epigenetics , B cell differentiation , T cell differentiation , Immunology

Research theme for competitive and other funds (13)：

2019 - 2022 Roles of a non-coding RNA that regulates normal and neoplastic T cell development
2018 - 2020 Dissection of immune cell differentiation by a single cel epigenome analysis
2017 - 2020 Role of Polycomb proteins in lymphocyte cell fate decision
2017 - 2020 Identification of miRNA which rescues EBF1 deficiency indispensable for B cell lineage commitment
2016 - 2018 SIngle-cell transcriptional networks during B cell differentiation

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Papers (52)：

Jin J, Ogawa T, Hojo N, Kryukov K, Shimiz K, Ikawa T, Imanishi T, Okazaki T, and Shiroguchi K. Robotic data acquisition with deep learning enables cell image-based prediction of transcriptomic phenotypes. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2023. 2210283120. e2210283120. e2210283120
Yosuke Nagahata, Kyoko Masuda, Yuji Nishimura, Tomokatsu Ikawa, Shinpei Kawaoka, Toshio Kitawaki, Yasuhito Nannya, Seishi Ogawa, Hiroshi Suga, Yutaka Satou, et al. Tracing the evolutionary history of blood cells to the unicellular ancestor of animals. Blood. 2022. 140. 24. 2611-2625
Junichiro Takano, Shinsuke Ito, Yixing Dong, Jafar Sharif, Yaeko Nakajima-Takagi, Taichi Umeyama, Yong-Woon Han, Kyoichi Isono, Takashi Kondo, Yusuke Iizuka, et al. PCGF1-PRC1 links chromatin repression with DNA replication during hematopoietic cell lineage commitment. Nature Communications. 2022. 13. 1. 7159-7159
Ogawa T, Ochiai K, Iwata T, Ikawa T, Tsuzuki T, Shiroguchi K and Takahashi K. Different cell imaging methods did not significantly improve immune cell image classification performance. PLoS One. 2022. 17. 1. e0262397
Ochiai K, Yamaoka M, Swaminathan A, Shima H, Hiura H, Matsumoto M, Kurotaki D, Nakabayashi J, Funeyama R, Nakayama K, Arima T, Ikawa T, Tamura T, Sciammas R, Bouvet P, Kundu TK, Igarashi K. Chromatin protein PC4 orchestrates B cell differentiation by collaborating with IKAROS and IRF4. Cell Reports. 2020. 33. 12. 108517-108538

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MISC (14)：

伊川友活. 転写因子とマクロファージ分化. 臨床免疫・アレルギー科. 2021. 75. 699-706
藥師寺那由他, 伊川友活. B細胞分化を駆動する転写プログラムとクロマチン制御. 臨床免疫・アレルギー科. 2019. 71. 215-222
宮井智浩, 伊川友活. 多能性前駆細胞からB細胞への分化における段階的転写制御. 臨床免疫・アレルギー科. 2018. 70. 503-513
Bidisha Chanda, Tomokatsu Ikawa, Kazuki Okuyama, Katsuto Hozumi, Kiyoshi Ando, Arinobu Tojo, Hiroshi Kawamoto, Ai Kotani. EBF Deficient Hematopoietic Progenitor Cells Potentialy Differentiated into Immature B Cell: EBF1 Dispensable for B Cell Linage Commitment from Pro-B to Pre-B Stage. BLOOD. 2014. 124. 21
Bidisha Chanda, Tomokatsu Ikawa, Kazuki Okuyama, Katsuto Hozumi, Kiyoshi Ando, Arinobu Tojo, Hiroshi Kawamoto, Ai Kotani. EBF Deficient Hematopoietic Progenitor Cells Potentialy Differentiated into Immature B Cell: EBF1 Dispensable for B Cell Linage Commitment from Pro-B to Pre-B Stage. BLOOD. 2014. 124. 21

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Lectures and oral presentations (42)：

合成免疫学の魅力〜免疫系は「調べる」時代から「創る」時代へ〜
(第51回日本免疫学会 2022)
The function of Polycomb group proteins during B cell development
(第51回日本免疫学会 2022)
Generation of genetically engineered TCR-T cells from self-renewing multipotent progenitor cells
(第51回日本免疫学会 2022)
The roles of transcription factors PU.1, IRF4, and IRF8 in regulation of the genes expressed in dendritic cells
(第51回日本免疫学会学術集会 2022)
iLS細胞を用いた白血病治療モデル
(令和4年度 HM-SCREEN 班会議 2022)

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Professional career (1)：

Ph.D (Kyoto University)

Committee career (3)：

2023/05/28 - 2028/06/18 Kyoto T Cell Conference administration officer
2021/01/01 - 2024/12/31 Japanese Society for Immunology councilor
2018/08 - 2022/08 Japanese Society of Interferon & Cytokine Research exective board

Association Membership(s) (3)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE SOCIETY OF HEMATOLOGY , THE JAPANESE SOCIETY FOR IMMUNOLOGY

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