Rchr
J-GLOBAL ID:201801000240951876   Update date: Jan. 19, 2023

Yuu Miyauchi

ミヤウチ ユウ | Yuu Miyauchi
Affiliation and department:
Job title: 講師
Research field  (3): Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - health and biochemistry ,  Pharmaceuticals - health and biochemistry
Research keywords  (5): 終末糖化産物 ,  タンパク質間相互作用 ,  核内受容体 ,  小胞体 ,  薬物代謝
Research theme for competitive and other funds  (11):
  • 2022 - 2024 シトクロムP450による肝障害惹起の機構解明:終末糖化産物に対する感受性の上昇
  • 2022 - 2023 シトクロムP450による肝毒性発現の機構解明:終末糖化産物に対する感受性の上昇
  • 2020 - 2023 Suppression of oxidative stress by protein-protein interaction between cytochrome P450 and UDP-glucuronosyltransferase
  • 2021 - 2022 炎症反応が薬物代謝酵素の複合体形成に与える影響:薬物代謝活性低下の新規機構
  • 2020 - 2022 Quantitative analysis of drug metabolizing enzymes forming complex
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Papers (21):
  • Madoka Sawai, Yuu Miyauchi, Takumi Ishida, Shinji Takechi. Dihydropyrazine suppresses TLR4-dependent inflammatory responses by blocking MAPK signaling in human hepatoma HepG2 cells. The Journal of Toxicological Sciences. 2022. 47. 9. 381-387
  • Yuu Miyauchi, Akane Kimura, Madoka Sawai, Keiko Fujimoto, Yuko Hirota, Yoshitaka Tanaka, Shinji Takechi, Peter I Mackenzie, Yuji Ishii. Use of a Baculovirus-Mammalian Cell Expression-System for Expression of Drug-Metabolizing Enzymes: Optimization of Infection With a Focus on Cytochrome P450 3A4. Frontiers in pharmacology. 2022. 13. 832931-832931
  • Shoji Nakamura, Ryohei Yamashita, Yuu Miyauchi, Yoshitaka Tanaka, Yuji Ishii. Adenine-related compounds modulate UDP-glucuronosyltransferase (UGT) activity in mouse liver microsomes. Xenobiotica; the fate of foreign compounds in biological systems. 2021. 51. 11. 1-25
  • Hong-Bin Chen, Jorge Carlos Pineda Garcia, Shinako Arizono, Tomoki Takeda, Ren-Shi Li, Yukiko Hattori, Hiroe Sano, Yuu Miyauchi, Yuko Hirota, Yoshitaka Tanaka, et al. DAPL1 is a novel regulator of testosterone production in Leydig cells of mouse testis. Scientific reports. 2021. 11. 1. 18532-18532
  • The in Vitro Inhibitory Effects of Nobiletin, a Polymethoxyflavonoid from Citrus Depressa, on the Hepatic Enzyme Activity of Dams Maternally Exposed to Low-Dose 2,3,7,8-Tetrachlorodibenzo-p-dioxin. 2021. 112. 2. 136-147
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MISC (9):
  • 宮内優. 奨励賞を受賞して. 日本薬物動態学会ニュースレター. 2022. 37. 6
  • Yuu Miyauchi. [Protein-Protein Interactions as Underlying Regulatory Mechanisms of Drug-metabolizing Enzyme Function]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2022. 142. 11. 1169-1175
  • 宮内 優. 万病のもと「糖化産物」:生命にとって不可欠な糖がもたらすリスク. 環境・衛生薬学トピックス. 2022
  • 宮内 優. 甘いだけではない糖との関係:終末糖化産物 (AGEs) による不妊の惹起. ファルマシア. 2020. 56. 10
  • 宮内 優. 学会道しるべ: 12th International ISSX Meetingに参加して. 日本薬物動態学会ニュースレター. 2019. 34. 5
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Education (3):
  • 2012 - 2015 九州大学大学院 薬学府 創薬科学専攻博士後期課程
  • 2010 - 2012 九州大学大学院 薬学府 創薬科学専攻修士課程
  • 2006 - 2010 Kyushu University School of Pharmaceutical Sciences
Professional career (2):
  • 修士(創薬科学) (九州大学大学院薬学府)
  • 博士(創薬科学) (九州大学大学院薬学府)
Work history (4):
  • 2020/04 - 現在 Faculty of Pharmaceutical Sciences, Sojo University Laboratory of Hygienic Chemistry Senior Assistant Professor
  • 2016/11 - 2020/03 Kyushu University Faculty of Pharmaceutical Sciences
  • 2015/05 - 2016/11 National Institute of Environmental Health Sciences (NIEHS) Pharmacogenetics Group Visiting Fellow
  • 2015/04 - 2015/04 Kyushu University Faculty of Pharmaceutical Sciences
Committee career (1):
  • 2021/04 - 現在 日本薬学会「ファルマシア」 トピックス小委員
Awards (9):
  • 2022/12 - 崇城大学 令和3年度ベストリサーチアワード
  • 2022/11 - The Japanese Society for the Study of Xenobiotics JSSX Award for Young Scientists
  • 2022/07 - 崇城大学 令和3年度ベストティーチング賞
  • 2021/11 - 日本薬学会 九州山口支部 学術奨励賞
  • 2021/09 - 日本薬学会 環境・衛生部会 部会賞・金原賞
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Association Membership(s) (5):
American Society for Pharmacology and Experimental Therapeutics ,  International Society for the Study of Xenobiotics ,  THE JAPANESE SOCIETY OF TOXICOLOGY ,  THE JAPANESE SOCIETY FOR THE STUDY OF XENOBIOTICS ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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