Rchr
J-GLOBAL ID:201801000287031457   Update date: Nov. 02, 2024

Tanaka Yoshio

Tanaka Yoshio
Affiliation and department:
Job title: Professor
Research field  (1): Pharmacology
Research keywords  (5): n-3 unsaturated fatty acid ,  BK channel ,  urinary bladder smooth muscle ,  Smooth muscle contraction/relaxation mechamism ,  adrenoceptor
Research theme for competitive and other funds  (22):
  • 2024 - 2027 n-3系PUFAはストア作動性Caチャネルを標的として気管平滑筋の収縮を抑制する
  • 2024 - 2027 フェルラ酸は血小板活性化因子(PAF)による膀胱平滑筋の過活動を改善する
  • 2023 - 2026 α-リノレン酸は脳動脈収縮を即時的かつDHA・EPAに匹敵するほど強力に抑制する
  • 2021 - 2024 下部泌尿器平滑筋の収縮機能異常に対するγ-リノレン酸の抑制効果の分子基盤
  • 2020 - 2023 Mechanisms which underlie the immediate inhibitory effects by n-3 polyunsaturated fatty acids of coronary artery contraction
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Papers (186):
  • Keisuke Obara, Kento Yoshioka, Yoshio Tanaka. Platelet-activating Factor (PAF) in Urinary Bladder Smooth Muscle (UBSM): Its Novel Role as a Potential Inducer of Detrusor Overactivity and the Mechanisms Underlying Its Effects in Enhancing UBSM Mechanical Activities. YAKUGAKU ZASSHI. 2024. 144. 11. 997-1007
  • Keisuke Obara, Yuki Usami, Risa Okamoto, Kento Yoshioka, Yoshio Tanaka. Evaluation of inhibitory actions of antidepressants on muscarinic receptors assessed by a binding assay in the mouse cerebral neocortex. Journal of Pharmacological Sciences. 2024
  • Keisuke Obara, Kento Yoshioka, Yoshio Tanaka. Effects of Platelet-Activating Factor (PAF) on the Mechanical Activities of Lower Urinary Tract and Genital Smooth Muscles. Biological and Pharmaceutical Bulletin. 2024. 47. 9. 1467-1476
  • Kento Yoshioka, Keisuke Obara, Mikoto Ozawa, Mayu Kiguchi, Yuri Nakao, Hinako Miyaji, Toma Yamashita, Noboru Saitoh, Yutaka Nakagome, Yoshio Tanaka. Alpha-linolenic acid selectively inhibits the contraction of pig coronary arteries mediated through prostanoid TP receptors. Journal of pharmacological sciences. 2024. 155. 4. 148-151
  • Keyue Xu, Miyuki Shimizu, Toma Yamashita, Mako Fujiwara, Shunya Oikawa, Guanghan Ou, Naho Takazakura, Taichi Kusakabe, Keisuke Takahashi, Keisuke Kato, et al. Inhibitory mechanisms of docosahexaenoic acid on carbachol-, angiotensin II-, and bradykinin-induced contractions in guinea pig gastric fundus smooth muscle. Scientific reports. 2024. 14. 1. 11720-11720
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MISC (168):
Professional career (1):
  • PhD
Association Membership(s) (3):
JAPAN SOCIETY OF SMOOTH MUSCLE RESEARCH ,  THE JAPANESE PHARMACOLOGICAL SOCIETY ,  THE PHARMACEUTICAL SOCIETY OF JAPAN
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