Rchr
J-GLOBAL ID:201801000402964594
Update date: Oct. 26, 2024
Fujihara Chiharu
Fujihara Chiharu
Affiliation and department:
Research field (4):
Mathematical analysis
, Regenerative dentistry and dental engineering
, Immunology
, Conservative dentistry and endodontics
Research keywords (1):
mathematical modeling
Research theme for competitive and other funds (16):
- 2022 - 2025 歯周病におけるFPR2シグナルを介した炎症収束機構の解明
- 2022 - 2025 細胞ダイバーシティーを基盤とした歯周組織幹細胞の運命決定機構の解明
- 2022 - 2024 多因子トランスオミックス解析で挑む口唇口蓋裂研究の新戦略
- 2021 - 2023 p-dentistry確立に向けた歯周病発症予測法の開発
- 2019 - 2023 統合オミクス解析に基づく侵襲性歯周炎の病態理解
- 2020 - 2023 歯周病進行の細菌・分子間ダイナミクス制御に基づく歯周病重症化予測診断法の開発
- 2019 - 2020 数理モデリングによる歯周組織再生メカニズムの解明と再生効果予測
- 2018 - 2020 歯周組織再生のための幹細胞コンピテンシーの解明と細胞移植治療への応用
- 2018 - 2019 NAD+中間代謝産物補充と老化細胞除去による 全身と歯周組織の健康寿命の延伸
- 2017 - 2019 歯周組織恒常性維持の統合的理解とホメオダイナミクス-歯周治療・診断への新戦略-
- 2017 - 2019 Mechanisms of activation of cement-PDL-bone complex by CD40-CD40L interaction
- 2017 - 2018 Elucidation of mechanisms of proliferation in periodontal ligament stem cells: analysis using database of patients suffering from aggressive periodontitis
- 2017 - 2017 Fibroblast growth factor-2 Inhibits CD40-mediated Periodontal Inflammation
- 2015 - 2017 Analysis of bone metabolism in B-cell-specific CD40 conditional knockout mice
- 2015 - 2017 Role of CD40 in Periodontal Inflammation
- 2009 - 2010 Analysis of novel periodontal ligament-specific molecules identified in human periodontal ligament full-length cDNA database.
Show all
Papers (42):
-
FUJIHARA Chiharu, KITAGAKI Jirouta, MATSUMOTO Masahiro, MASUMOTO Risa, SHIMABUKURO Yoshio, MURAKAMI Shinya. Association of CLSPN Variant rs115197921 with Aggressive Periodontitis and its Functional Analysis in Periodontal Ligament Cells. The Japanese Journal of Conservative Dentistry. 2024. 67. 5. 304-314
-
Risa Masumoto, Chiharu Fujihara, Masahiro Matsumoto, Jirouta Kitagaki, Shinya Murakami. Single nucleotide polymorphism rs854560 in paraoxonase-1 regulates the cytodifferentiation of human periodontal ligament cells. Frontiers in Dental Medicine. 2024. 5. 1449482
-
Chiharu Fujihara, Osa Amila Hafiyyah, Shinya Murakami. Identification of disease-associate variants of aggressive periodontitis using genome-wide association studies. Japanese Dental Science Review. 2023. 59. 357-364
-
Masaki Kinoshita, Satoru Yamada, Junichi Sasaki, Shigeki Suzuki, Tetsuhiro Kajikawa, Tomoaki Iwayama, Chiharu Fujihara, Satoshi Imazato, Shinya Murakami. Mice Lacking PLAP-1/Asporin Show Alteration of Periodontal Ligament Structures and Acceleration of Bone Loss in Periodontitis. International Journal of Molecular Sciences. 2023. 24. 21. 15989-15989
-
C. Fujihara, K. Murakami, S. Magi, D. Motooka, T. Nantakeeratipa, A. Canela, R. J. Tanaka, M. Okada, S. Murakami. Omics-Based Mathematical Modeling Unveils Pathogenesis of Periodontitis in an Experimental Murine Model. Journal of Dental Research. 2023. in press. 220345231196530
more...
MISC (41):
-
島袋善夫, 島袋善夫, 沢田啓吾, 小清水まみ, 品田和子, 浅井晴美, 溝口あゆみ, 林裕子, 塚本明奈, 宮後緑, et al. Patient Characterization according to the New Classification of Periodontitis and Performance of the Latter as a Predictor of Tooth Loss. 日本歯周病学会会誌(Web). 2021. 63. 3
-
松本 昌大, 藤原 千春, 島袋 善夫, 山本 優, Nantakeeratipat Teerachate, 北垣 次郎太, 八木 寛子, 林 聡子, 岩山 智明, 柏木 陽一郎, et al. 生物学的直接覆髄剤開発に向けた生理活性物質RVX-208の歯髄細胞における機能解析. 日本歯科保存学雑誌. 2020. 63. 6. 527-535
-
藤原千春, TEERACHATE Nantakeeratipat, WIBISANA Johannes Nicolaus, 飯田渓太, 井元宏明, 岡田眞里子, 村上伸也. オミクス解析を用いた歯周病における歯周組織破壊機構の理解. 日本分子生物学会年会プログラム・要旨集(Web). 2020. 43rd
-
木下 昌毅, 山田 聡, 藤原 千春, 佐々木 淳一, 下村 純平, 川嵜 公輔, 林 聡子, 粟田 敏仁, 津島 賢一朗, 竹立 匡秀, et al. ノックアウトマウスを用いたPLAP-1の歯根膜機械的機能解析. 日本歯周病学会会誌. 2019. 61. 秋季特別. 127-127
-
木下昌毅, 山田聡, 藤原千春, 佐々木淳一, 下村純平, 川嵜公輔, 林聡子, 粟田敏仁, 津島賢一朗, 竹立匡秀, et al. ノックアウトマウスを用いたPLAP-1の歯根膜機械的機能解析. 日本歯周病学会会誌(Web). 2019. 61
more...
Lectures and oral presentations (56):
-
Temporal Transcriptomic Insights into Periodontal Tissue Regeneration
(1st Asia & Pacific Bioinformatics Joint Conference 2024)
-
オミクス解析と数理モデリングによる歯周病進行の病態理解
(第5回「医学と数理」研究会 2024)
-
Non-symergistic interaction between periodontal pathogens and Ccl2 in periodontitis progression
(The 45th Annual Meeting of the Japanese Society of Inflammation and Regeneration 2024)
-
The localization and timing of MCP-1 expression during periodontitis progression
(2024)
-
オミクス解析と数理モデリングによる歯周病進行の病態理解と口腔疾患解明への展望
(広島大学理学部・理学研究科 2023)
more...
Works (2):
-
Complete Gene Expression Profile of Human Periodontal Ligaments
Yamada S 2016 -
-
48-h stretched human periodontal ligament cells (GSE19118)
Chiharu Fujihara 2009 -
Education (2):
- 2005 - 2009 Osaka University Graduate School of Dentistry Department of Periodontology
- 1999 - 2005 Osaka University Dental School
Professional career (2):
- 学士 (歯学) (大阪大学)
- 博士 (歯学) (大阪大学)
Work history (5):
- 2017/10 - 現在 Osaka University Graduate School of Dentistry, Department of Periodontology Assistant professor
- 2017/01 - 2017/09 Osaka University Graduate School of Dentistry Specially appointed assistant professor
- 2015/04 - 2017/01 Osaka University Dental Hospital Translational research center Specially appointed assistant professor
- 2010/02 - 2015/03 National Institutes of Health NCI, EIB Visiting fellow
- 2009/04 - 2010/01 Osaka University Dental Hospital Periodontics Senior resident
Awards (6):
Association Membership(s) (5):
大阪大学歯学会
, THE JAPANESE SOCIETY FOR IMMUNOLOGY
, THE JAPANESE SOCIETY OF CONSERVATIVE DENTISTRY
, JAPANESE SOCIETY OF PERIODONTOLOGY
, 分子生物学会
Return to Previous Page