Hagihara Masaki

ハギハラマサキ | Hagihara Masaki

Affiliation and department：

Research field (2)： Molecular biochemistry , Biochemistry

Research keywords (6)： antisense , RNA , グアニン四重鎖 , ケミカルバイオロジー , Bioorganic Chemistry , Nucleic Acids Chemistry

Research theme for competitive and other funds (17)：

2023 - 2026 New technologies for RNA structural regulation that enables the control and analysis of cellular function
2022 - 2025 新規修飾アンチセンスを用いた標的選択的なRNAグアニン四重鎖安定化法の開発
2021 - 2025 日本発の革新的バイオ医薬開発を目指した細胞内RNA機能の制御機構の解明と創薬応用
2020 - 2023 Understanding Cellular Function with Short RNAs and Small Molecules
2016 - 2019 Development of a practical protein-chip using designed DNA-arrays

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Papers (52)：

Yousuke Katsuda, Shin-ichi Sato, Maimi Inoue, Hisashi Tsugawa, Takuto Kamura, Tomoki Kida, Rio Matsumoto, Sefan Asamitsu, Norifumi Shioda, Shuhei Shiroto, et al. Small molecule-based detection of non-canonical RNA G-quadruplex structures that modulate protein translation. Nucleic Acids Research. 2022
Masaki Hagihara, Chikara Dohno, Kaoru Saito, Kazuhiro Sugimoto, Yuta Hishinuma, Yuri Sohma, Tomonori Shibata, Kazuhiko Nakatani. Short Tandem Repeat Contractions during in vitro DNA Synthesis by Repeat-Binding Molecules. Chemistry Letters. 2021
Masaki Hagihara, Shuhei Shiroto, Shunya Igarashi, Shin-ichi Sato. Guanine-Tethered Oligonucleotides Restore Abnormal Protein Synthesis with a SNP Mutation in a 5’-UTR G-quadruplex of Human MSH2. Chemistry Letters. 2021
Chikara Dohno, Masaki Hagihara, Nursakinah Binti Mohd Zaifuddin, Mizuki Nihei, Kaoru Saito, Kazuhiko Nakatani. Small molecule-induced trinucleotide repeat contractions during in vitro DNA synthesis. Chemical communications (Cambridge, England). 2021
Yasuhiko Yamamoto, Haruka Araki, Ryosuke Shinomiya, Kosuke Hayasaka, Yusaku Nakayama, Kentaro Ochi, Tomokazu Shibata, Atsuya Momotake, Takako Ohyama, Masaki Hagihara, et al. Structures and Catalytic Activities of Complexes between Heme and All Parallel-Stranded Monomeric G-Quadruplex DNAs. Biochemistry, in press. 2018

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MISC (11)：

嘉村匠人, 勝田陽介, 北村祐介, 萩原正規, 佐藤慎一, 井原敏博. A nucleic acid medicine against PAH based on the construction of RNA G-quadruplex structure. 日本核酸医薬学会年会講演要旨集(CD-ROM). 2022. 7th
勝田陽介, 嘉村匠人, 北村裕介, 萩原正規, 佐藤慎一, 井原敏博. G-quadruplexを利用したRNA faction検出法の開発. 日本分析化学会講演要旨集. 2018. 67年会. 104-104
武井史恵, 萩原正規, ZHANG Jinhua, 中谷和彦. Application for The Fluorescent Detection of Single Nucleotide Difference using N, N’-bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine. 日本化学会講演予稿集. 2006. 86th. 2
T. Hasegawa, M. Hagihara, S. Sato, K. Ohkubo, T. Morii, S. Yoshikawa. Development of a Nanobiodevice based Ribonucleopeptide Complex. The 2nd International Symposium on Sustainable Energy System,Kyoto University Clock Tower Centennial Hall, Kyoto (Japan),2004.12.17-18. 2004
Y. Tanabe, M. Hagihara, S. Sato, K. Ohkubo, T. Morii. Tailoring receptors and sensors from an RNA-peptide assmebly. International symposium on Nano-organization and Function,Tokyo,2004.11.11-12. 2004

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Patents (4)：

Books (3)：

Methods in Molecular Biology, Vol. 1111, P. 197-208
Springer 2014
Chembiomolecular Science, At the Frontier of Chemistry and Biology, P. 59-67
Springer 2011
Peptide Revolution: Genomics, Proteomics & Therapeutics. P. 556-558
American Peptide Society 2004

Education (3)：

Work history (7)：

2012/04 - 現在 Hirosaki University Graduate School of Science and Technology
2007/04 - 2012/03 Osaka University The Institute of Scientific and Industrial Research
2005/07 - 2007/03 Osaka University The Institute of Scientific and Industrial Research
2005/04 - 2005/06 Osaka University The Institute of Scientific and Industrial Research
2004/09 - 2005/03 科学技術振興機構博士研究員(京都大学中谷和彦助教授)

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Committee career (1)：

Awards (1)：

Association Membership(s) (2)：

JAPANESE SOCIETY FOR CHEMICAL BIOLOGY , THE CHEMICAL SOCIETY OF JAPAN

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