Rchr
J-GLOBAL ID：201801000602802840   Update date: Mar. 03, 2024

Okuyama Kohei

オクヤマ コウヘイ | Okuyama Kohei
Affiliation and department：
The University of Texas MD Anderson Cancer Center Department of Head and Neck Surgery,

About The University of Texas MD Anderson Cancer Center Department of Head and Neck Surgery,


Job title： Postdoctoral Fellow
Research field  (4)： Tumor biology ,  Cell biology ,  Tumor diagnostics and therapeutics ,  Surgical dentistry
Research keywords  (6)： Cancer-associated nerve ,  Epithelial-mesenchymal transition ,  Cancer-associated fibroblast ,  Cancer microenvironment ,  Cancer Stem Cell ,  Head and Neck Cancer
Research theme for competitive and other funds  (7)：
  • 2024 - 2027 頭頸部がん微小環境における腫瘍関連神経とCAFsのクロストークの解明
  • 2023 - 2026 Cetuximab長期投与が及ぼす腫瘍細胞のpyroptosisへの影響
  • 2021 - 2024 The predictive factor on the cancer treatment with pembrolizumab.
  • 2021 - 2024 The prolonged cetuximab treatment effect for the dynamics of cell cytoskeleton and intracellular protein transportation in tongue squamous cell carcinoma cell.
  • 2022 - 口腔癌発生過程における免疫寛容獲得メカニズムの解明
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Papers (42)：
  • Kohei Okuyama, Tomofumi Naruse, Souichi Yanamoto. Tumor Microenvironment Modulation by Cetuximab and its Contribution to Subsequent Immune-Checkpoint Inhibition Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma. Journal of Oral and Maxillofacial Surgery. 2023. 81. 9. S76-S77
  • Kohei Okuyama, Hiromasa Fukushima, Tomofumi Naruse, Souichi Yanamoto. Cell-in-cell structure in cancer: evading strategies from anti-cancer therapies. Frontiers in Oncology. 2023. 13. 1248097
  • Okuyama, K., Naruse, T., Yanamoto, S. Tumor microenvironmental modification by the current target therapy for head and neck squamous cell carcinoma. Journal of Experimental and Clinical Cancer Research. 2023. 42. 1. 114
  • Blake R. Heath, Wang Gong, Hülya F. Taner, Luke Broses, Kohei Okuyama, Wanqing Cheng, Max Jin, Zackary R. Fitzsimonds, Andriana Manousidaki, Yuesong Wu, et al. Saturated fatty acids dampen the immunogenicity of cancer by suppressing STING. Cell Reports. 2023. 42. 4. 112303
  • Kohei Okuyama, Keiji Suzuki, Souichi Yanamoto. Relationship between Tumor Budding and Partial Epithelial-Mesenchymal Transition in Head and Neck Cancer. Cancers. 2023. 15. 4. 1111
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MISC (12)：
  • Kohei Okuyama, Tomofumi Naruse, Souichi Yanamoto. Tumor Microenvironment Modulation by Cetuximab and its Contribution to Subsequent Immune-Checkpoint Inhibition Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma. Journal of Oral and Maxillofacial Surgery. 2023. 81. 9. S76-S77
  • 奥山 紘平, 鳴瀬 智史, 柳本 惣市, 土橋 宏輝, 戒田 篤志, 三浦 雅彦, 梅田 正博. セツキシマブの長期処理がもたらす舌癌細胞遊走能の抑制は p27Kip1 依存性 G1 アレスト とオートファジーを誘導する. 第39回 日本口腔腫瘍学会森会•学術大会 プログラム・抄録集. 2021. 29
  • 黒嶋 雄志, 小野里祐佑, 及川 悠, 奥山 紘平, 大迫 利光, 釘本 琢磨, 平井 秀明, 富岡 寛文, 島本 裕彰, 道 泰之, et al. 舌扁平上皮癌における舌リンパ節転移の臨床病理学的検討. 第39回 日本口腔腫瘍学会森会•学術大会 プログラム・抄録集. 2021. 12
  • 奥山紘平, 加島義久, 平井秀明, 横川美咲, 山形優子, 道 泰之, 富岡寛文, 土谷麻衣子, 栢森 高, 池田 通, et al. Two cases of epithelial-myoepithelial carcinoma arising in the hard palate. 日本口腔腫瘍学会総会・学術大会プログラム・抄録集. 2021. 39th
  • 奥山紘平, 鈴木啓司, 鳴瀬智史, 柳本惣市, 梅田正博, 三浦雅彦, 原田浩之. セツキシマブによる頭頸部扁平上皮癌細胞の高度の細胞運動能低下は遅発性に抗腫瘍効果をもたらす. 第79回 日本癌学会総会記事 PJ6-2. 2020
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Books (1)：
  • 月刊「細胞」10月臨時増刊号
    New Science, Co. Ltd 2023
Lectures and oral presentations  (61)：
  • Tumor Microenvironment Modulation by Cetuximab and its Contribution to Subsequent Immune-Checkpoint Inhibition Therapy in Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma
    (105th American Association of Oral and Maxillofacial Surgeons (AAOMS), Annual Meeting 2023)
  • BATF2 suppresses cancer initiation by promoting γδ T-cell-mediated immunity
    (IOTN Semi-Annual SC Meeting 2023)
  • Resolving an Immune Tolerogenic Niche at the Earliest Phase of Oral Cancer Initiation
    (AACR ANNUAL MEETING 2023 2023)
  • IL-1α Mediated Suppressive Myeloid Function in Head and Neck Cancer
    (The 52nd meeting of the AADOCR, and 47th meeting of the CADR 2023)
  • Sox2-driven Epithelial Transformation Promotes IL1-mediated Peripheral Immune Tolerance
    (University of Michigan School of Dentistry Research Day 2023 2023)
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Education (2)：
  • 2012 - 2016 Department of Maxillofacial Surgery, Division of Maxillofacial and Neck Reconstruction, Graduate School of Tokyo Medical and Dental University, Tokyo, Japan.
  • 2005 - 2011 Tohoku University School of Dentistry
Professional career (1)：
  • Ph.D (Dentistry) (Tokyo Medical and Dental University)
Work history (11)：
  • 2023/11 - 現在 The University of Texas MD Anderson Cancer Center Department of Head and Neck Surgery Postdoctoral Fellow
  • 2022/12 - 現在 Department of Cell Biology, Nagasaki University Graduate School of Biomedical Sciences Adjunct Lecturer
  • 2022/07 - 現在 東京医科歯科大学大学院医歯学総合研究科顎口腔腫瘍外科学分野 (名称変更) 非常勤講師
  • 2021/09 - 2023/10 University of Michigan School of Dentistry Department of Periodontics & Oral Medicine Postdoctoral Research Fellow
  • 2021/09 - 2023/10 University of Michigan Rogel Cancer Center
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Committee career (1)：
  • 2023/01 - 現在 Oncology Letters (Spandidos Publications) : Editorial Board Member
Awards (7)：
  • 2021/12 - AME Publishing Company Reviewer of the Month / Translational Cancer Research (TCR) /
  • 2016/05 - 独立行政法人日本学生支援機構 (JASSO) 「特に優れた業績をあげた大学院第一種奨学生に対する返還免除制度」による第一種奨学金返還免除(全額)
  • 2016/01 - Annual Meeting of Japanese Society of Oral Oncology Poster award
  • 2015/10 - 60th Annual Meeting of Japanese Society of Oral and Maxillofacial Surgery Poster award
  • 2015/05 - 15th International Congress of Radiation Research (ICRR) Young Investigators Travel Award
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Association Membership(s) (8)：
JAPANESE SOCIETY OF DENTISTRY FOR MEDICALLY COMPROMISED PATIENT ,  JAPANESE STOMATOLOGICAL SOCIETY ,  THE JAPANESE CANCER ASSOCIATION ,  JAPAN SOCIETY FOR HEAD AND NECK CANCER ,  JAPANESE SOCIETY OF ORAL ONCOLOGY ,  JAPANESE SOCIETY OF ORAL AND MAXILLOFACIAL SURGEONS ,  Japan Oral Oncology Group ,  日本口腔診断学会
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