Hirano Tetsushi

ヒラノテツシ | Hirano Tetsushi

Affiliation and department：

Research field (2)： Hygiene and public health (laboratory) , Environmental effects of chemicals

Research theme for competitive and other funds (15)：

2023 - 2027 Creation of a platform for the evaluation of signal toxicity, starting with the development of methods for the detection and diagnosis of brain function disruption.
2022 - 2025 Elucidation of mechanisms of generational toxicology of developmental neurotoxicity - Developmental program and epigenomic toxicity of pesticides
2023 - 2025 神経炎症に起因する神経毒性に関するメカニズム解明と新規バイオマーカーの開発
2022 - 2025 Construction and practice of MITA system for more sensitive and efficient toxicity testing
2022 - 2024 神経炎症を介した農薬類の神経毒性機序の解明とmicroRNAバイオマーカーの同定

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Papers (48)：

Anri Hirai, Chitoku Toda, Yared Beyene Yohannes, Nimako Collins, Mai Tamba, Kei Nomiyama, Akifumi Eguchi, Nobuhiko Hoshi, Tetsushi Hirano, Shouta M M Nakayama, et al. Role of brain monoamines in acetamiprid-induced anxiety-like behavior. Toxicology. 2024. 153839-153839
Tetsushi Hirano, Shuji Ohno, Yoshinori Ikenaka, Kanoko Onaru, Shizuka Kubo, Yuka Miyata, Mizuki Maeda, Youhei Mantani, Toshifumi Yokoyama, Collins Nimako, et al. Quantification of the tissue distribution and accumulation of the neonicotinoid pesticide clothianidin and its metabolites in maternal and fetal mice. Toxicology and applied pharmacology. 2024. 116847-116847
Yukako Hara, Asuka Shoda, Sakura Yonoichi, Yuya Ishida, Midori Murata, Mako Kimura, Makiko Ito, Sarika Nunobiki, Ayano Yoshimoto, Youhei Mantani, et al. No-observed-adverse-effect-level (NOAEL) clothianidin, a neonicotinoid pesticide, impairs hippocampal memory and motor learning associated with alteration of gene expression in cerebellum. The Journal of veterinary medical science. 2024
Yuya Ishida, Sakura Yonoichi, Yukako Hara, Asuka Shoda, Mako Kimura, Midori Murata, Makiko Ito, Sarika Nunobiki, Ayano Yoshimoto, Youhei Mantani, et al. Effect of clothianidin exposure at the no-observed-adverse-effect level (NOAEL) in a mouse model of atopic dermatitis. The Journal of veterinary medical science. 2024
Sakura Yonoichi, Yukako Hara, Yuya Ishida, Asuka Shoda, Mako Kimura, Midori Murata, Sarika Nunobiki, Makiko Ito, Ayano Yoshimoto, Youhei Mantani, et al. Effects of exposure to the neonicotinoid pesticide clothianidin on α-defensin secretion and gut microbiota in mice. The Journal of veterinary medical science. 2024

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MISC (2)：

平野哲史. 複数の化学物質が中枢神経系に及ぼす複合リスク評価. Endocrine Disrupter News Letter (Web). 2023. 25. 4
表原拓也, 永堀健太, 河田晋一, 李忠連, 宮宗秀伸, 伊藤正裕, 南貴一, 万谷洋平, 梅村ゆりあ, 西田美穂, et al. ニワトリ胚におけるセルトリ細胞の起源(The origin of Sertoli cells in the chicken embryo). 東京医科大学雑誌. 2018. 76. 1. 139-140

Lectures and oral presentations (99)：

フィプロニル代謝物が引き起こすミクログリアの活性化がエクソソームを介してニューロンに及ぼす影響
(The Journal of Toxicological Sciences 2023)
フィプロニル代謝物によるミクログリアの活性化およびエクソソーム分泌を介したニューロンへの作用
(環境化学物質3学会合同大会要旨集 2023)
低出力パルス超音波による骨分化誘導促進作用におけるアクチン細胞骨格の関与の検討
(超音波医学 2023)
胎子授乳期ネオニコチノイド系農薬曝露が海馬記憶と小脳運動学習機能に及ぼす継世代影響
(日本獣医学会学術集会講演要旨集 2023)
HeLa細胞の温熱誘導細胞障害に対するBag3の細胞保護作用:その機能ドメインの役割解析
(Thermal Medicine 2022)

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Education (2)：

2013 - 2017 Kobe University Graduate School of Agricultural Science Department of Bioresource Science
2009 - 2013 Kobe University Faculty of Agriculture Department of Bioresource Science

Professional career (1)：

博士(農学) (神戸大学)

Work history (3)：

2019/10 - 現在富山大学学術研究部薬学・和漢系助教
2017/04 - 現在 University of Toyama
2016/04 - 2017/03 日本学術振興会特別研究員 DC2

Committee career (2)：

2022/06 - 環境化学物質3学会合同大会実行委員
2022/05 - 日本内分泌撹乱物質学会(環境ホルモン学会) 評議員

Awards (2)：

2022/06 - 環境化学物質3学会合同大会日本内分泌撹乱物質学会(環境ホルモン学会) 森田賞
2021/07 - 日本毒性学会第48回日本毒性学会学術年会優秀研究発表賞

Association Membership(s) (3)：

日本内分泌撹乱物質学会(環境ホルモン学会) , THE JAPANESE SOCIETY OF TOXICOLOGY , Society of Toxicology

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