Rchr
J-GLOBAL ID:201801000703926620   Update date: Jun. 04, 2024

Inoue Minoru

Inoue Minoru
Affiliation and department:
Research field  (2): Radiology ,  Tumor biology
Research keywords  (10): microendoscopy ,  edge computing ,  Intravital imaging ,  Reactive Oxygen Species ,  Serum albumin ,  Radiation Therapy ,  Neutrophil Extracellular Traps ,  Redox Homeostasis ,  Cancer ,  Radiation Biology
Research theme for competitive and other funds  (8):
  • 2024 - 2027 放射線抵抗性腫瘍への応用を見据えたIn vivoフェロトーシス誘導法の開発
  • 2021 - 2024 放射線照射により生じる血管内酸化ストレス及びがん転移形質の誘導機構の解明
  • 2022 - 2023 腫瘍内モザイク強度放射線治療の実現を見据えた腫瘍内顕微観察法の開発
  • 2020 - 2021 プレシジョン放射線治療の実現を見据えた機械学習によるがん放射線感受性予測法の開発
  • 2019 - 2021 血清アルブミンの酸化度に基づくがんの放射線感受性予測法の開発
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Papers (27):
  • Noriko Kishi, Masahiro Yoneyama, Hiroyuki Inoo, Minoru Inoue, Hiraku Iramina, Akiyoshi Nakakura, Tomohiro Ono, Hideaki Hirashima, Takanori Adachi, Norimasa Matsushita, et al. Protocol of a phase II study to evaluate the efficacy and safety of deep-inspiration breath-hold daily online adaptive radiotherapy for centrally located lung tumours (PUDDING study). Radiation oncology (London, England). 2024. 19. 1. 32-32
  • Minoru Inoue, Yusuke Iizuka, Kiyonao Nakamura, Genki E Sato, Takashi Mizowaki. Role of albumin Cys34 redox state in the progression of differentiated thyroid carcinoma and induction of ferroptosis. Free radical biology & medicine. 2023. 209. Pt 1. 108-115
  • Yoshiko Doi, Yasushi Nagata, Yasuo Matsumoto, Kazushi Numata, Ryu Sasaki, Takashi Yamada, Hiroshi Igaki, Toshiyuki Imagumbai, Norio Katoh, Tadamasa Yoshitake, et al. Multicenter retrospective study of stereotactic body radiotherapy for patients with previously untreated initial small hepatocellular carcinoma. Hepatology research : the official journal of the Japan Society of Hepatology. 2023. 53. 8. 749-760
  • Yusuke Iizuka, Tomohiro Katagiri, Kengo Ogura, Minoru Inoue, Ryota Nakashima, Kiyonao Nakamura, Takashi Mizowaki. Recurrence-free survival and prognosis after adjuvant therapy with radioactive iodine-131 in patients with differentiated thyroid carcinoma. Scientific reports. 2023. 13. 1. 10795-10795
  • Hajime Torizuka, Minoru Inoue, Yusuke Iizuka, Yosuke Yamada, Takashi Mizowaki. Anaplastic Transformation of Follicular Thyroid Carcinoma in Pulmonary Metastasis With Gradually Progressive Intra-tumoral Cavitation: A Case Report. Cureus. 2022. 14. 11. e31999
more...
MISC (3):
  • 井上実, 吉村通央, BRATMAN Scott V., LIU Fei-Fei, 溝脇尚志. 抗NETs療法による転移性肺腫瘍の予防戦略. 日本癌治療学会学術集会(Web). 2020. 58th
  • 井上 実, 吉村 通央, 溝脇 尚志, Liu Fei-Fei, Bratman Scott V. アルブミン酸化により生じる酸化還元バランス不均衡は肺優位なNETosisと転移を促進する(Plasma Redox Imbalance Caused by Albumin Oxidation Promotes Lung-Predominant NETosis and Metastasis). 日本癌学会総会記事. 2019. 78回. E-1076
  • 小林 稔, 曽 麗華, 後藤 容子, 井上 実, 板坂 聡, 吉村 通央, 原田 浩, 平岡 真寛. IDH3はHIF-1alphaを安定化して腫瘍増殖を亢進する. 2013
Lectures and oral presentations  (7):
  • Inhibition of the forward-mode sodium-calcium exchange induces infection-independent NETotic cell death via activation of NADPH oxidase
    (2021 SfRBM & MCW Redox Biology Symposium 2021)
  • Plasma Redox Imbalance Caused by Albumin Oxidation Promotes Lung-Predominant NETosis and Metastasis in Patients Treated With Definitive Radiation Therapy
    (2018 ASTRO annual meeting 2018)
  • Intravascular redox balance regulates NETosis and cancer metastasis
    (Multidisciplinary Head and Neck Cancers Symposium 2018)
  • Starvation condition triggers neutrophil extracellular traps
    (Personalizing Cancer Medicine in 2016 Conference 2016)
  • PLK1 blockade enhances therapeutic effects of radiation by inducing cell cycle arrest at the mitotic phase
    (2014)
more...
Education (2):
  • 2011 - 2015 京都大学大学院 医学研究科博士課程
  • 2000 - 2006 Hamamatsu University School of Medicine Faculty of Medicine School of Medicine
Professional career (1):
  • 博士(医学) (京都大学)
Work history (4):
  • 2023/12 - Shizuoka Cancer Center, Research Institute
  • 2018/04 - 2023/11 Kyoto University Hospital Department of Radiation Oncology Assistant Professor
  • 2015/04 - 2018/03 University of Toronto, Princess Margaret Cancer Centre Postdoctoral Fellow
  • 2009/04 - 2011/03 静岡県立静岡がんセンター 放射線治療科 非常勤医師
Awards (2):
  • 2021/10 - Society for Leukocyte Biology Abstract Award Inhibition of Na+/Ca2+ exchanger activates NADPH oxidase and induces NETosis
  • 2018/10 - American Society for Radiation Oncology Abstract Award(Basic/Translational Science Award) Plasma Redox Imbalance Caused by Albumin Oxidation Promotes Lung-Predominant NETosis and Metastasis in Patients Treated With Definitive Radiation Therapy
Association Membership(s) (6):
Society for Leukocyte Biology ,  Society for Redox Biology and Medicine ,  JAPAN SOCIETY OF CLINICAL ONCOLOGY ,  THE JAPANESE CANCER ASSOCIATION ,  JAPAN RADIOLOGICAL SOCIETY ,  JAPANESE SOCIETY FOR RADIATION ONCOLOGY
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