Rchr
J-GLOBAL ID：201801000732538400   Update date: Nov. 07, 2024

Kentaro Sahashi

サハシ ケンタロウ | Kentaro Sahashi
Affiliation and department：
Nagoya University Graduate School of Medicine Department of Neurology

About Nagoya University Graduate School of Medicine Department of Neurology


Homepage URL  (1)： https://nrid.nii.ac.jp/ja/nrid/1000090710103/
Research field  (2)： Neuropathology ,  Neurology
Research keywords  (5)： spinal muscular atrophy ,  antisense oligonucleotide ,  ポリグルタミン病 ,  タウオパチー ,  motor neuron disease
Research theme for competitive and other funds  (28)：
  • 2024 - 2027 孤発性ALS病態を反映した動物モデル作成とTDP-43凝集抑制療法の開発
  • 2024 - 2026 ALSに関連する運動ニューロン周囲オリゴデンドロサイトの機能と役割の解明
  • 2024 - 2026 神経変性疾患に対する先駆的核酸創薬研究
  • 2023 - 2026 Elucidation of temporal alteration in motor neuron-oligodendrocyte interaction in motor neuron diseases
  • 2022 - 2025 Therapeutic development against protein aggregation
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Papers (35)：
  • 辻河 高陽, 佐橋 健太郎, 勝野 雅央. 【タウ研究update】タウ凝集と細胞骨格の関連. Dementia Japan. 2024. 38. 2. 196-204
  • Masaki Hirano, Kentaro Sahashi, Yuki Ichikawa, Masahisa Katsuno, Atsushi Natsume. A rapid and easy-to-use spinal muscular atrophy screening tool based on primers with high specificity and amplification efficiency for SMN1 combined with single-stranded tag hybridization assay. PloS one. 2024. 19. 8. e0308179
  • Tomoyuki Kazuta, Ayuka Murakami, Seiya Noda, Satoko Hirano, Hiroshi Kito, Koyo Tsujikawa, Hirotaka Nakanishi, Seigo Kimura, Kentaro Sahashi, Haruki Koike, et al. Clinicopathological features of graft versus host disease-associated myositis. Annals of clinical and translational neurology. 2023
  • Tomoki Hirunagi, Hideaki Nakatsuji, Kentaro Sahashi, Mikiyasu Yamamoto, Madoka Iida, Genki Tohnai, Naohide Kondo, Shinichiro Yamada, Ayuka Murakami, Seiya Noda, et al. Exercise attenuates polyglutamine-mediated neuromuscular degeneration in a mouse model of spinal and bulbar muscular atrophy. Journal of cachexia, sarcopenia and muscle. 2023
  • Mayumi Kataoka, Kentaro Sahashi, Koyo Tsujikawa, Jun-Ichi Takeda, Tomoki Hirunagi, Madoka Iida, Masahisa Katsuno. Dysregulation of Aldh1a2 underlies motor neuron degeneration in spinal muscular atrophy. Neuroscience research. 2023
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MISC (27)：
  • 佐橋 健太郎, 勝野 雅央. 【治る,予防できる脳神経疾患-現状と将来】運動ニューロン疾患発症予防に向けた創薬開発. 医学のあゆみ. 2024. 289. 12. 892-897
  • 伊藤 大輔, 佐橋 健太郎, 勝野 雅央. 本年の動向 SOD1変異ALSに対する核酸医薬. Annual Review神経. 2024. 2024. 89-94
  • 佐橋 健太郎. 核酸医薬治療の最前線 脊髄性筋萎縮症に対するアンチセンス核酸治療. 日本内科学会雑誌. 2024. 113. 臨増. 98-99
  • 佐橋 健太郎, 勝野 雅央. 【核酸医薬と神経疾患】疾患治療 脊髄性筋萎縮症(成人). Clinical Neuroscience. 2023. 41. 5. 713-715
  • 佐橋 健太郎, 勝野 雅央. 【遺伝性神経・筋疾患-診療と研究の最前線】その他の神経・筋疾患の病態・診断・治療法開発 脊髄性筋萎縮症の治療法確立とその先. 医学のあゆみ. 2022. 283. 10. 1024-1031
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Patents (9)：
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Education (2)：
  • 2004 - 2008 Nagoya University Graduate School of Medicine (Ph.D.)
  • 1993 - 1999 Nagoya University Graduate School of Medicine (M.D.)
Work history (4)：
  • 2023/05 - 現在 Nagoya University Graduate School of Medicine Department of Neurology Associate professor
  • 2020/11 - 2023/04 Nagoya University Hospital
  • 2016/11 - 2020/10 Nagoya University Hospital Hospital Center for postgraduate clinical training and career development
  • 2008/09 - 2013/03 Cold Spring Harbor Laboratory
Association Membership(s) (4)：
THE JAPANESE SOCIETY OF INTERNAL MEDICINE ,  JAPANESE SOCIETY OF NEUROLOGY ,  日本核酸医薬学会 ,  日本神経治療学会
※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

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