Waseda Masazumi

ワセダマサズミ | Waseda Masazumi

Affiliation and department：

Research field (4)： Immunology , Tumor diagnostics and therapeutics , Cell biology , Molecular biology

Research keywords (7)： Chimeric Antigen Receptor (CAR) , T cell differentiation , Oncolytic virus , Regenerative medicine , induced Pluripotent Stem cells , Cytotoxic T cells , Cancer immunotherapy

Research theme for competitive and other funds (2)：

2022 - 2025 優れた抗腫瘍効果を発揮する再生T細胞療法実現のための新規T細胞分化系の開発
2019 - 2022 ヒト膵臓がん細胞株の麻疹ウイルス感染制御機構の解明

Papers (9)：

Akihiro Ishikawa, Masazumi Waseda, Tomoko Ishii, Mika K Kaneko, Yukinari Kato, Shin Kaneko. Improved anti-solid tumor response by humanized anti-podoplanin chimeric antigen receptor transduced human cytotoxic T cells in an animal model. Genes to cells : devoted to molecular & cellular mechanisms. 2022. 27. 9. 549-558
Bo Wang, Shoichi Iriguchi, Masazumi Waseda, Norihiro Ueda, Tatsuki Ueda, Huaigeng Xu, Atsutaka Minagawa, Akihiro Ishikawa, Hisashi Yano, Tomoko Ishi, et al. Generation of hypoimmunogenic T cells from genetically engineered allogeneic human induced pluripotent stem cells. Nature Biomedical Engineering. 2021. 5. 5. 429-440
Masazumi Waseda, Shin Kaneko. Podoplanin as an Attractive Target of CAR T Cell Therapy. Cells. 2020
Masazumi Waseda, Sumimasa Arimura, Eri Shimura, Susumu Nakae, Yuji Yamanashi. Loss of Dok-1 and Dok-2 in mice causes severe experimental colitis accompanied by reduced expression of IL-17A and IL-22. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. 2016. 478. 1. 135-142
Kawakami, T., Akai, Y., Fujimoto, H., Kita, C., Aoki, Y., Konishi, T., Waseda, M., Takemura, L., Aimoto, S. Sequential peptide ligation by combining the CysPro ester (CPE) and thioester methods and its application to the synthesis of histone H3 containing a trimethyl lysine residue. Bulletin of the Chemical Society of Japan. 2013. 86. 6. 690-697

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MISC (2)：

早稲田真澄, 金子新. 人工胸腺オルガノイドからのCAR-T細胞の分化. 実験医学増刊. 2023. 41. 2
Masazumi Waseda, Shin Kaneko. Development of Regenerative Cancer Immunotherapy using iPS Cell Technologies. 2018. 34. 1

Lectures and oral presentations (2)：

MODELING CANCER IMMUNOTHERAPY IN A PERFUSABLE 3D VASCULARIZED TUMOR-ON-A-CHIP USING HLA-KO UNIVERSAL HUMAN IPSC-DERIVED ENDOTHELIAL CELLS
(ISSCR 2020 Virtual 2020)
Modeling cancer immunotherapy in a perfusable 3D vascularized tumor-on-a-Chip using universal iPSC-derived endothelial cells.
(CiRA 2019 International Symposium 2019)

Education (3)：

2011 - 2015 東京大学大学院医学系研究科病因・病理学専攻
2009 - 2011 Kobe University Graduate School of Medicine Faculty of Biomedical Sciences
2005 - 2009 Osaka University School of Science Department of Chemistry

Work history (2)：

2018/04 - 現在京都大学iPS細胞研究所金子新研究室特定研究員
2016/08 - 2018/03 京都大学iPS細胞研究所金子新研究室教務補佐員

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