Le Thi Thanh Thuy

レティタントゥイ | Le Thi Thanh Thuy

Affiliation and department：
Job title： Associate Professor

Research field (1)： Gastroenterology

Research theme for competitive and other funds (10)：

2023 - 2026 慢性肝疾患において肝線維化が改善すると門脈圧は低下するか?その限界はどこか?
2022 - 2025 肝細胞のがん化における細胞間相互作用を介した星細胞の役割
2022 - 2025 Novel anti-fibrotic properties of heme binding proteins including Neuroglobin, Myoglobin, and Hemoglobin in comparison with Cytoglobin in vitro and in vivo
2021 - 2024 Cytoglobin (CYGB)-overexpression and targeted demethylation of CYGB promoter impair liver and pancreatic tumor growth
2021 - 2024 B型肝炎の治療抵抗性および病態進展における免疫チェックポイント分子の関与

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Papers (36)：

Ngo Vinh Hanh, Le Thi Thanh Thuy, Vu Ngoc Hieu, Hoang Hai, Hiroko Ikenaga, Misako Sato-Matsubara, Sawako Uchida-Kobayashi, Hayato Urushima, Nguyen Van Khanh, Nguyen Thi Ha, et al. Poorly Differentiated Hepatocellular Carcinoma Cells Avoid Apoptosis by Interacting with T Cells via CD40-CD40 Ligand Linkage. The American journal of pathology. 2024. 194. 7. 1230-1247
Elena Porto, Joey De Backer, Le Thi Thanh Thuy, Norifumi Kawada, Thomas Hankeln. Transcriptomics of a cytoglobin knockout mouse: Insights from hepatic stellate cells and brain. Journal of inorganic biochemistry. 2024. 250. 112405-112405
Masaru Enomoto, Cheng-Hao Tseng, Yao-Chun Hsu, Le Thi Thanh Thuy, Mindie H Nguyen. Collaborating with AI in literature search-An important frontier. Hepatology communications. 2023. 7. 12
Yoshinori Okina, Misako Sato-Matsubara, Yasutoshi Kido, Hayato Urushima, Atsuko Daikoku, Chiho Kadono, Yu Nakagama, Yuko Nitahara, Truong Huu Hoang, Le Thi Thanh Thuy, et al. Nitric Oxide Derived from Cytoglobin-Deficient Hepatic Stellate Cells Causes Suppression of Cytochrome c Oxidase Activity in Hepatocytes. Antioxidants & redox signaling. 2023. 38. 7-9. 463-479
Savneet Kaur, Srivatsan Kidambi, Martí Ortega-Ribera, Le Thi Thanh Thuy, Natalia Nieto, Victoria C Cogger, Wei-Fen Xie, Frank Tacke, Jordi Gracia-Sancho. In Vitro Models for the Study of Liver Biology and Diseases: Advances and Limitations. Cellular and molecular gastroenterology and hepatology. 2023. 15. 3. 559-571

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Lectures and oral presentations (6)：

Insight profiling of non-parenchymal cells in liver fibrosis progression and regression by single-cell RNA sequencing analysis
(22nd International Symposium on Cells of Hepatic Sinusoid (ISCHS) 2024)
Single-cell RNA sequencing analysis of non-parenchymal cells in liver fibrosis progression and regression
(Asian Pacific Association for the Study of the Liver (APASL) 2024)
. Cell-cell interaction of LSECs-HSCs in the microenvironment of Diethyl nitrosamine treated Cytoglobin Knock-out mice
(Asian Pacific Association for the Study of the Liver (APASL) 2024)
Characteristics of consultation contents of Vietnamese migrants receiving free health consultations in Tokyo and Osaka
(The Global Health Joint Conference 2023)
Interaction between HSC and LSEC populations in the premalignant environment of DEN-treated Cytoglobin knock-out mice
(Asian Pacific Association for the Study of the Liver (APASL) STC Oncology 2023)

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