Rchr
J-GLOBAL ID:201801000820485074   Update date: Sep. 24, 2024

Makoto Shirakawa

シラカワ マコト | Makoto Shirakawa
Affiliation and department:
Research field  (4): Clinical pharmacy ,  Pharmaceuticals - analytical and physicochemistry ,  Neurosurgery ,  Radiology
Research keywords  (4): イオン液体 ,  Liposome ,  Drug Delivery System ,  Boron Neutron Capture Therapy
Research theme for competitive and other funds  (13):
  • 2023 - 2026 Development of a novel multifunctional nanoliposome-based system for maintaining active agent concentration in tumor tissue during boron-neutron capture therapy
  • 2023 - 2026 ホウ素中性子捕捉療法の承認薬(p-boronophenylalanine)に対する新規水溶性溶媒の開発
  • 2022 - 2025 BNCT用ホウ素薬剤BPAの溶解度向上による治療効果改善を目指した製剤学的研究
  • 2019 - 2022 Boron distribution study for newly developed BNCT agents
  • 2019 - 2022 Evaluation of a novel drug (BAMP) for Boron Neutron Capture Therapy
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Papers (27):
  • Takuya Fujimoto, Osamu Yamasaki, Noriyuki Kanehira, Hirokazu Matsushita, Yoshinori Sakurai, Naoya Kenmotsu, Ryo Mizuta, Natsuko Kondo, Takushi Takata, Mizuki Kitamatsu, et al. Overcoming immunotherapy resistance and inducing abscopal effects with boron neutron immunotherapy (B-NIT). Cancer science. 2024
  • Makoto Shirakawa. [Chasing New Cancer Treatments: Current Status and Future Development of Boron Neutron Capture Therapy]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. 2024. 144. 9. 871-876
  • Kengo Banshoya, Yoshiharu Kaneo, Makoto Shirakawa, Yuhzo Hieda, Aoi Machida, Masatoshi Ohnishi, Tetsuro Tanaka. Preparation and in vitro evaluation of amphotericin B-loaded nano-formulations for both intravenous and ophthalmic administration using 3-aminophenylboronic acid-conjugated styrene-maleic acid copolymers. Journal of Drug Delivery Science and Technology. 2023. 90. 105176-105176
  • Kengo Banshoya, Makoto Shirakawa, Yuhzo Hieda, Masatoshi Ohnishi, Yuhki Sato, Atsuko Inoue, Tetsuro Tanaka, Yoshiharu Kaneo. A Novel Amphotericin B Hydrogel Composed of Poly(Vinyl Alcohol)/Borate Complex for Ophthalmic Formulation. Chemical & pharmaceutical bulletin. 2023. 71. 1. 70-73
  • Yuhki Sato, Ayana Michihara, Yuka Nagatsuka (Handa, Kouichi Yamamoto, Makoto Shirakawa, Hirokazu Katayama. High performance liquid chromatography coupled with mass spectrometry for simultaneous determination of rivastigmine and its metabolite in rat plasma. Acta Chromatographica. 2021
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MISC (14):
  • 海渡遥菜, 有田はるか, 亀川展幸, 竹内亮太, 堀均, 堀均, 本田真知子, 今重之, 佐藤雄己, 白川真, et al. Analysis of therapeutic effect by BAMP developed for BNCT. 日本薬学会年会要旨集(Web). 2021. 141年会. 29P01-090S
  • 坂居知憲, 中野智恵美, 堀均, 奥田綾, 杉山正明, 重永章, 佐藤雄己, 白川真, 白川真. Synthesis of a novel boron compounds added nuclear translocation abilities by a peptides. 日本薬学会年会要旨集(Web). 2021. 141st
  • 石原和樹, 河上清香, 亀川展幸, 竹内亮太, 堀均, 堀均, 中井啓, 松村明, 佐藤雄己, 白川真, et al. Development of novel formulation Using Ionic Liquids for insoluble amino acid BPA. 日本薬学会年会要旨集(Web). 2020. 140th
  • 白川真, 白川真, 大本拓実, 重藤真希, 中井啓, 吉田文代, 竹内亮太, 堀均, 堀均, 松村明, et al. 新規PEG化ホウ素化合物の生体内分布とBNCTによる治療効果の評価. 日本薬学会年会要旨集(CD-ROM). 2019. 139th
  • 白川真, 白川真, 柏田啓江, 中井啓, 中井啓, 吉田文代, 栗林ひかり, 南田幸子, 松村明, 冨田久夫. 新規ホウ素リポソーム製剤の生体内分布とその治療効果の評価. 日本薬学会年会要旨集(CD-ROM). 2018. 138th
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Patents (1):
  • ホウ素クラスター修飾PEG脂質誘導体およびこれを用いたリポソーム
Education (3):
  • 2009 - 2013 University of Tsukuba Graduate School of Comprehensive Human Sciences
  • 2007 - 2009 University of Tsukuba Graduate School of Comprehensive Human Sciences
  • 2003 - 2007 Toho University Faculty of Pharmaceutical Sciences School of Pharmaceutical Sciences
Professional career (1):
  • 博士(医学) (筑波大学)
Work history (8):
  • 2023/09 - 現在 Okayama University Neutron Therapy Research Center
  • 2014/01 - 2024/03 University of Tsukuba Faculty of Medicine
  • 2019/04 - 2023/09 Fukuyama University
  • 2016/04 - 2019/03 Fukuyama University Faculty of Pharmacy and Pharmaceutical Sciences
  • 2015/03 - 2019/03 味の素株式会社 研究コンサルティング (兼任)
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Awards (5):
  • 2022/11 - 日本薬学会中国四国支部 奨励賞
  • 2019/09 - 日本中性子捕捉療法学会 ベストプレゼンテーション賞
  • 2018/03 - 福山大学 教員表彰
  • 2017/11 - 9th young researcher’s Boron Neutron Capture Therapy Best Presentation Award
  • 2010/10 - 14th International Congress on Neutron Capture Therapy Fairchild Award
Association Membership(s) (6):
Sigma Xi ,  THE PHARMACEUTICAL SOCIETY OF JAPAN ,  日本中性子捕捉療法学会 ,  イオン液体研究会 ,  日本薬剤学会 ,  THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM
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