Hasebe Takashi

ハセベタカシ | Hasebe Takashi

Affiliation and department：

Research field (1)： Structural biochemistry

Research theme for competitive and other funds (7)：

2017 - 2021 Identification of genes specific to the intestinal epithelial stem cells and their functional analysis by making use of transgenic frogs
2015 - 2018 Lineage analysis of intestinal stem cells and development of the culture system to study the stem cell niche
2013 - 2017 Origin of the adult epithelial stem cell in the Xenopus laevis intestine and the role of Notch signaling in the stem cell regulation
2012 - 2015 Molecular mechanisms of development of the stem cell niche regulating intestinal epithelial dedifferentiation
2010 - 2014 The study for the mechanism of steroid hormone-dependent sex determination in amphibians

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Papers (48)：

Kenta Fujimoto, Yuki Shibata, Takashi Hasebe. Thyroid Hormone-Activated Signaling Pathways are Essential for Development of Intestinal Stem Cells. Journal of Nippon Medical School = Nippon Ika Daigaku zasshi. 2023. 90. 3. 246-252
Takashi Hasebe, Kenta Fujimoto, Atsuko Ishizuya-Oka. Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the amphibian intestine during metamorphosis. Vitamins and hormones. 2023. 122. 1-22
Takashi Hasebe, Kenta Fujimoto, Atsuko Ishizuya-Oka. Essential roles of YAP-TEAD complex in adult stem cell development during thyroid hormone-induced intestinal remodeling of Xenopus laevis. Cell and tissue research. 2022
Takashi Hasebe, Kenta Fujimoto, Atsuko Ishizuya-Oka. Thyroid hormone-induced expression of Foxl1 in subepithelial fibroblasts correlates with adult stem cell development during Xenopus intestinal remodeling. Scientific reports. 2020. 10. 1. 20715-20715
Takashi Hasebe. Stem cell development involves divergent thyroid hormone receptor subtype expression and epigenetic modifications in the Xenopus metamorphosing intestine. General and comparative endocrinology. 2020. 292. 113441-113441

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MISC (2)：

Takashi Hasebe, Rebecca Hartman, Liezhen Fu, Tosikazu Amano, Yun-Bo Shi. Evidence for a cooperative role of gelatinase A and membrane type-1 matrix metalloproteinase during Xenopus laevis development (vol 124, pg 11, 2007). MECHANISMS OF DEVELOPMENT. 2007. 124. 5. 407-408
Fujimori Hisashi, Iwata Takeo, Hasebe Takashi, Obinata Takashi, Kikuyama Sakae. CLONING OF A NOVEL ISOFORM OF PARVALBUMIN cDNA FROM THE SKELETAL MUSCLE OF THE BULLFROG, RANA CA TESBEIANA(Endocrinology,Abstracts of papers presented at the 74^<th> Annual Meeting of the Zoological Society of Japan) :. Zoological science. 2003. 20. 12. 1607-1607

Professional career (1)：

Work history (5)：

2022/04 - 現在 Nippon Medical School Department of Biology Professor
2012/04 - 2022/03 Nippon Medical School Department of Biology Associate Professor
2006/04 - 2012/03 Nippon Medical School Department of Biology Senior Assistant Professor
2003/04 - 2006/03 National Institutes of Health SMM/LGRD/NICHD Visiting Fellow
2000/04 - 2003/03 Waseda University Department of Biology, School of Education Research Associate

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