Rchr
J-GLOBAL ID:201801001239074264
Update date: Oct. 31, 2024
Park Eun Jeong
Park Eun Jeong
Affiliation and department:
Job title:
Associate Professor
Research field (2):
Pathobiochemistry
, Immunology
Research keywords (10):
MicroRNA
, Cell-adhesion molecules
, Innate lymphoid cell
, Sepsis
, Exosomes
, Extracellular vesicles
, Cell migration
, Inflammatory bowel diseases
, Intestinal epithelial cell
, Intestinal immunity
Research theme for competitive and other funds (16):
- 2024 - 2028 Development of a novel treatment and prognostic model for post-cardiac arrest syndrome using the M2 Macrophage Designer Exosome
- 2022 - 2025 Targeting integrin signaling for the treatment of COVID-19
- 2022 - 2025 Elucidation of role of thrombomodulin in recovery of mucosal tissue in inflammatory bowel disease
- 2022 - 2025 Identifying PD-L1-mediated immune dysregulation in post-cardiac arrest syndrome.
- 2022 - 2025 Exosomes and miRNAs of intestinal epithelial cells regulate inflammations in sepsis
- 2021 - 2024 Elucidation of the mechanism by which exosomal PD-L1 induces septic immune paralysis
- 2021 - 2024 ILC2 exhaustion and metabolic dysregulation in septic myopathy: implications of PD-L1 exosomes
- 2021 - 2024 Development of integrin-targeted therapy for novel coronavirus-induced ARDS
- 2019 - 2024 Trans-Kingdom RNA Interference Elicited by Thai Traditional Medicinal Plant-derived MicroRNAs for Anti-Inflammation
- 2019 - 2022 Elucidation of role of thrombomodulin in recovery of mucosal tissue in inflammatory bowel disease
- 2019 - 2022 Study of the anti-inflammatory roles of the exosomes from intestinal epithelial cells in sepsis via a paracrine effect
- 2018 - 2021 Exosomal regulation of leukocyte trafficking
- 2016 - 2019 The peritoneum omentum exosomes in the septic immune paralysis
- 2016 - 2019 Examination of regulatory network profiles for gene expression of intestinal epithelial barrier dysfunction in aging
- 2016 - 2018 The ability of human extracellular vesicles to augment inflammatory host response in septic shock
- 2016 - 2018 Interaction between beta2 integrin and thrombomodulin effect to immunothrombosis
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Papers (69):
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Arong Gaowa, Supasuta Leangpanich, Eun Jeong Park, Eiji Kawamoto, Motomu Shimaoka. Irisin promotes intestinal epithelial cell proliferation via Wnt/β-catenin and focal adhesion kinase signaling pathways. Scientific reports. 2024. 14. 1. 25702-25702
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Yuichi Akama, Eun Jeong Park, Naoko Satoh-Takayama, Atsushi Ito, Eiji Kawamoto, Arong Gaowa, Eri Matsuo, Satoshi Oikawa, Masafumi Saito, Shigeaki Inoue, et al. Roles of programmed death-1 and muscle innate lymphoid cell-derived interleukin 13 in sepsis-induced intensive care unit-acquired weakness. Journal of cachexia, sarcopenia and muscle. 2024
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Khwanchanok Mokmued, Gideon Obeng, Eiji Kawamoto, Siqingaowa Caidengbate, Supasuta Leangpanich, Yuichi Akama, Arong Gaowa, Motomu Shimaoka, Eun Jeong Park. miR-200c-3p regulates α4 integrin-mediated T cell adhesion and migration. Experimental cell research. 2024. 440. 2. 114146-114146
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Ryo Esumi, Asami Ito-Masui, Eiji Kawamoto, Mami Ito, Tomoyo Hayashi, Toru Shinkai, Atsuya Hane, Fumito Okuno, Eun Jeong Park, Ryuji Kaku, et al. Correlation Between Social Network Structure and Well-being of Healthcare Workers in Intensive Care Units: A Prospective Observational Study. Interactive Journal of Medical Research. 2023
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Takanori Yamaguchi, Arong Gaowa, Eun Jeong Park, Isao Tawara, Motomu Shimaoka. Recombinant soluble thrombomodulin attenuates cisplatin-induced intestinal injury by inhibiting intestinal epithelial cell-derived cytokine secretion. Molecular Biology Reports. 2023. 50. 10. 8459-8467
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MISC (58):
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Mokmued Khwanchanok, Obeng Gideon, Matsuo Eri, Gaowa Arong, Shimaoka Motomu, Park Eun Jeong. miRNA-200c-3p controls alpha4beta7 integrin-mediated T-cell adhesion and migration. 第52回 日本免疫学会総会・学術集会記録. 2023. 52. Proceedings. 149-149
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Arong Gaowa, Yamaguchi Takanori, Park Eun Jeong, Shimaoka Motomu. 組換え型可溶性トロンボモジュリンは腸上皮細胞由来のサイトカイン分泌を抑制することでシスプラチンによる胃腸障害を抑制する(Recombinant soluble thrombomodulin attenuates cisplatin-induced intestinal injury by inhibiting intestinal epithelial cell-derived cytokine secretion). 第52回 日本免疫学会総会・学術集会記録. 2023. 52. Proceedings. 380-380
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朴 恩正, 島岡 要. 腸管上皮細胞のマイクロRNA分析から,敗血症に特徴的な臓器特異的炎症反応制御の複雑さが見える. 細胞. 2023. 55. 11. 898-901
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朴 恩正, Caidengbate Siqingaowa, 赤間 悠一, Banerjee Anik, Mokmued Khwanchanok, 川本 英嗣, 阿栄高娃, Lee Juneyoung, McCullough Louise D., 島岡 要. 敗血症モデルマウスの腸管上皮細胞のマイクロRNAプロファイル. Shock: 日本Shock学会雑誌. 2023. 37. 1. 83-83
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Gaowa Arong, Park Eun Jeong, Shimaoka Motomu. Mucosal and Skin Surface Barrier(Irisin promotes intestinal epithelial cell proliferation via Wnt/beta-catenin and integrin beta 1/FAK signaling pathway). 日本免疫学会総会・学術集会記録(0919-1984)51巻Proceedings. 2022. 51. WS19-09-P
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Patents (5):
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Detoxified mutants of Escherichia coli heat-labile enterotoxin
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Nucleic acid encoding angiogenesis inhibitor
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A novel angiogenesis inhibitor
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Novel angiogenesis inhibitor
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Angiogenesis inhibitor
Books (3):
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Mucosal Vaccines (Ed. Hiroshi Kiyono): Innovation for Preventing Infectious Diseases. 2nd Edition
Elsevier 2020
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Examination of immunological memory induced by MucoRice-CTB, a rice-based oral vaccine.
The Tojuro Iijima Foundation for Food Science and Technology (Annual Report) 2014
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Leukocyte Adhesion (Ed. Klaus Ley). Current Topics in Membranes, Volume 64
Elsevier 2009
Lectures and oral presentations (63):
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miRNA-200c-3p controls alpha4beta7 integrin-mediated T-cell adhesion and migration
(52nd Annual Meeting of Japanese Society for Immunology 2024)
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Recombinant soluble thrombomodulin attenuates cisplatin-induced intestinal injury by inhibiting intestinal epithelial cell-derived cytokine secretion
(52nd Annual Meeting of Japanese Society for Immunology 2024)
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Dynamic Functionalities of Cellular and Exosomal Integrins
(Invited Seminar (Faculty of Medicine, Thammasat University) 2023)
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MicroRNA Profiles in Intestinal Epithelial Cells in a Mouse Model of Sepsis
(37th Annual Meeting of Japan Shock Society 2023)
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Irisin promotes intestinal epithelial cell proliferation via Wnt/beta-catenin and integrin beta 1/FAK signaling pathway
(51st Annual Meeting of Japanese Society for Immunology 2022)
more...
Education (3):
- 2000 - 2004 Osaka University Graduate School of Medicine Course of Molecular Medicine
- 1993 - 1995 Sungkyunkwan University College of Science Biological Sciences
- 1986 - 1993 Sungkyunkwan University College of Science Biological Sciences
Professional career (1):
Work history (6):
Committee career (1):
- 2009 - 2010 Immune Disease Institute Institutional Animal Care and Use Committee Member
Awards (5):
- 2019/01 - Mie University Medical School/Graduate School of Medicine Education Contribution Award
- 2016/04 - Mie Prefecture Healthcare Management Center Research Scientific Award Mechanism of mucosal immune system down-regulation induced by colon cancer
- 2013/04 - Japan Society of Nutrition and Food Science Scientific Research Award Examination of immunological memory induced by MucoRice-CTB, a rice-based oral vaccine
- 2009 - GlaxoSmithKline-Immune Disease Institute Alliance Research Fellowship Award
- 2003 - Yoneyama Rotary Foundation Scholarship
Association Membership(s) (3):
THE JAPANESE SOCIETY FOR IMMUNOLOGY
, THE JAPANESE SOCIETY ON THROMBOSIS AND HEMOSTASIS
, The Japan Shock Society
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