Toshiaki Shirai

シライトシアキ | Toshiaki Shirai

Affiliation and department：
Job title： Assistant Professor
Research theme for competitive and other funds (1)：

Papers (21)：

Tomoyuki Sasaki, Osamu Inoue, Shinji Ogihara, Kayo Kubokawa, Saori Oishi, Toshiaki Shirai, Keisuke Iwabuchi, Katsue Suzuki-Inoue. Detection of SARS-CoV-2 RNA Using RT-qPCR in Saliva Samples and Nasopharyngeal, Lingual, and Buccal Mucosal Swabs. JAPANESE JOURNAL OF INFECTIOUS DISEASES. 2022. 75. 1. 102-104
Shimon Otake, Tomoyuki Sasaki, Toshiaki Shirai, Nagaharu Tsukiji, Shogo Tamura, Katsuhiro Takano, Yukio Ozaki, Katsue Suzuki-Inoue. CLEC-2 stimulates IGF-1 secretion from podoplanin-positive stromal cells and positively regulates erythropoiesis in mice. Journal of Thrombosis and Haemostasis. 2021. 19. 6. 1572-1584
Heme activates platelets, exacerbates rhabdomyolysis-induced acute kidney injury via CLEC, GPVI/FcRγ. Heme activates platelets and exacerbates rhabdomyolysis-induced acute kidney injury via CLEC-2 and GPVI/FcRγ. Blood Advances. 2021. 5. 7. 2017-2026
大竹志門, 大石沙織, 築地長治, 大石直輝, 佐々木知幸, 白井俊光, 高野勝弘, 近藤哲夫, 井上克枝. ヘミンはCLEC-2とGPVI/FcRγを介して血小板を活性化し、横紋筋融解による急性腎障害を悪化させる. 日本透析医会雑誌. 2021. 36. 1. 141-145
Suguru Maruyama, Hiroshi Kono, Shinji Furuya, Hiroki Shimizu, Ryo Saito, Katsutoshi Shoda, Hidenori Akaike, Naohiro Hosomura, Yoshihiko Kawaguchi, Hidetake Amemiya, et al. Platelet C-Type Lectin-Like Receptor 2 Reduces Cholestatic Liver Injury in Mice. AMERICAN JOURNAL OF PATHOLOGY. 2020. 190. 9. 1833-1842

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Lectures and oral presentations (46)：

Cancer-associated fibroblasts promote venous thrombosis through C-type lectin-like receptor 2/podoplanin in 3LL lung cancer mouse model
(ISTH2022 2022)
癌関連線維芽細胞はCLEC-2/PDPNを介して癌関連血栓症を増悪させる
(第44回日本血栓止血学会学術集会 2022)
硫酸化多糖カラギーナンはCLEC-2依存症に血小板を活性化する
(第44回日本血栓止血学会学術集会 2022)
CLEC-2 promotes IGF-1 secretion from PDPN+ stromal cells and positively regulates erythropoiesis
(第83回日本血液学会学術集会 2021)
横紋筋融解症に併発する腎障害における血小板CLEC-2及びGPVIの役割
(第43回日本血栓止血学会学術集会 2021)

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Education (1)：

Professional career (4)：

Awards (3)：

2020/07/01 - 一般社団法人日本血栓止血学会学術奨励賞(基礎) C-type Lectin-Like Receptor 2 Promotes Hematogenous Tumor Metastasis and Prothrombotic State in Tumor-Bearing Mice
2019/07/09 - Early Career Award
2018/12/03 - ASH Abstract Achievement Award

Association Membership(s) (2)：

The Japanese Society on Thrombosis and Hemostasis , International Society on Thrombosis and Haemostasis

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