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J-GLOBAL ID：201801001493101891   Update date: Jan. 30, 2024

Funakoshi Takeshi

フナコシ タケシ | Funakoshi Takeshi
Affiliation and department：
Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Public Health Forensic Medicine

About Tokyo Medical and Dental University Graduate School of Medical and Dental Sciences Medical and Dental Sciences Public Health Forensic Medicine


Job title： Assistant Professor
Homepage URL  (1)： http://www.tmd.ac.jp/med/legm/legm-J.html
Research field  (1)： Medical biochemistry
Research keywords  (2)： 細胞生化学 ,  中毒学
Research theme for competitive and other funds  (14)：
  • 2017 - 2019 水溶性一酸化炭素発生剤を用いた新規毒性機序の探索
  • 2016 - 2018 ヒ素による細胞死とオートファジー、プロテアソーム系の関与について
  • 2016 - 2018 ターゲットメタボローム法を用いた網羅的薬物毒性機序の解析と新規毒性評価法の研究
  • 2013 - 2015 オミクスの手法を統合したトキシコオミクスによる薬毒物中毒の分子機構解析
  • 2013 - 2015 ヒ素中毒の機序についての分子生化学的研究
Show all
Papers (43)：
  • Shuheng Wen, Kana Unuma, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura. Contraction Band Necrosis with Dephosphorylated Connexin 43 in Rat Myocardium after Daily Cocaine Administration. International journal of molecular sciences. 2022. 23. 19
  • Sho Aoki, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura. Aggregation-prone A53T mutant of α-synuclein exaggerates methamphetamine neurotoxicity in SH-SY5Y cells: Protective role of cellular cholesterol. Toxicol Rep. 2022. 9. 2020-2029
  • Unuma K, Kaga H, Funakoshi T, Nomura M, Aki T, Uemura K. Thymic involution caused by repeated cocaine administration includes apoptotic cell loss followed by ectopic adipogenesis. PloS one. 2022. 17. 11. e0277032
  • Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura. Inverse regulation of GSDMD and GSDME gene expression during LPS-induced pyroptosis in RAW264.7 macrophage cells. Apoptosis. 2022
  • Shuheng Wen, Kana Unuma, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura. Altered cardiac mitochondrial dynamics and biogenesis in rat after short-term cocaine administration. Scientific reports. 2021. 11. 1. 24129-24129
ｍore...
MISC (3)：
  • Shuheng Wen, Toshihiko Aki, Takeshi Funakoshi, Kana Unuma, Koichi Uemura. Role of Mitochondrial Dynamics in Cocaine's Neurotoxicity. International journal of molecular sciences. 2022. 23. 10
  • Toshihiko Aki, Kanako Noritake, Takeshi Funakoshi, Koichi Uemura. Modes of Chemically Induced Cell Death. Comprehensive Toxicology 3rd ed Volume 1 (General subjects). 2017
  • Toshihiko Aki, Takeshi Funakoshi, Koichi Uemura. Regulated necrosis and its implications in toxicology. Toxicology. 2015. 333. 118-126
Books (2)：
  • Comprehensive Toxicology 3rd ed Volume 1
    Elsevier UK 2018 ISBN:9780081006016
  • 差分解説 No.4860 薬毒物機器分析の精度向上と課題
    医事新報 2017
Lectures and oral presentations  (35)：
  • 増加するコカイン関連死の分析とコカイン臓器毒性の実験的検討
  • コカイン短期間投与のラット心筋ミトコンドリアのダイナミクスへの影響
    (第106次日本法医学会学術全国集会)
  • 持続型硫化水素発生剤に対する細胞応答のA549ヒト肺胞上皮細胞モデルを用いた検討
    (第90回日本法医学会学術関東地方集会)
  • 象牙質ラセミ化法による年齢推定における失活歯の影響について
    (第105次日本法医学会学術全国集会)
  • アリストロキア酸による近位尿細管細胞への細胞毒性の検討
    (第105次日本法医学会学術全国集会)
ｍore...
Association Membership(s) (3)：
法医中毒研究会 ,  日本法医学会 ,  日本分子生物学会
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