Kuwahara Yasumichi

クワハラヤスミチ | Kuwahara Yasumichi

Affiliation and department：
Job title： Associate professor

Research field (3)： Fetal medicine/Pediatrics , Medical biochemistry , Genomics

Research keywords (9)： Rhabdoid tumor , Chromatin Remodeling , SWI/SNF complex , SNF5 , RUNX1 , 小児悪性固形腫瘍 , Developmental Disorder , 行動分析学 , 行動医学

Research theme for competitive and other funds (13)：

2022 - 2025 Establishment of new intervention methods for hematopoietic transcriptional control for clinical application.
2022 - 2025 Functional analysis of transcription factors and novel SWI/SNF complexes in the tumorigenesis of rhabdoid tumors.
2019 - 2022 造血転写制御への新規介入方法の探索とその臨床応用に向けた研究
2019 - 2022 スーパーエンハンサー機能異常を介した悪性ラブドイド腫瘍の分子病態の解明
2019 - 2022 造血転写制御への新規介入方法の探索とその臨床応用に向けた研究

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Papers (38)：

Yaniv Kazansky, Daniel Cameron, Helen S Mueller, Phillip Demarest, Nadia Zaffaroni, Noemi Arrighetti, Valentina Zuco, Yasumichi Kuwahara, Romel Somwar, Marc Ladanyi, et al. Overcoming clinical resistance to EZH2 inhibition using rational epigenetic combination therapy. Cancer discovery. 2024
Yasumichi Kuwahara, Tomoko Iehara, Akifumi Matsumoto, Tsukasa Okuda. Recent insights into the SWI/SNF complex and the molecular mechanism of hSNF5 deficiency in rhabdoid tumors. Cancer medicine. 2023
Masamitsu Mikami, Tatsuya Masuda, Takuya Kanatani, Mina Noura, Katsutsugu Umeda, Hidefumi Hiramatsu, Hirohito Kubota, Tomoo Daifu, Atsushi Iwai, Etsuko Yamamoto Hattori, et al. RUNX1-Survivin Axis Is a Novel Therapeutic Target for Malignant Rhabdoid Tumors. Molecules and cells. 2022. 45. 12. 886-895
Haruka Shinohara, Rie Sawado, Makoto Nakagawa, Ayuna Hattori, Kazutsune Yamagata, Kimiharu Tauchi, Jumpei Ito, Yasumichi Kuwahara, Tsukasa Okuda, Chitose Ogawa, et al. Dual targeting of EZH1 and EZH2 for the treatment of malignant rhabdoid tumors. Molecular therapy oncolytics. 2022. 27. 14-25
Akifumi Matsumoto, Tatsushi Yoshida, Takahiro Shima, Kenta Yamasaki, Kenjiro Tadagaki, Noriko Kondo, Yasumichi Kuwahara, Dong-Er Zhang, Tsukasa Okuda. C11orf21, a novel RUNX1 target gene, is down-regulated by RUNX1-ETO. BBA Advances. 2022. 2. 100047

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MISC (21)：

岩橋瞳, 諸戸雅治, 桑原康通. 併存疾患を含む小児のASD,ADHD症例におけるWISC-IVのプロフィールの分析. 小児科. 2023. 64. 3. 263-270
隅田靖之, 福井勇人, 吉田秀樹, 諸戸雅治, 桑原康通. 心肺停止で搬送された両側緊張性気胸の14歳男児の1例. 日本救急医学会雑誌. 2020. 31. 8. 293-298
Hitomi Iwahashi,, Hiroaki Miya, Yasumichi Kuwahara. Successful intervention to improve an utterance behavior using behavioral therapy approach in a case with selective Mutism. Medical Journal of Fukuchiyama City Hospital. 2019. 4. 52-58
桑原康通, 忠垣憲次郎, 奥田司. 【がん研究・診療を巡る最新トピックス】エンハンサー制御と腫瘍発生. 京都府立医科大学雑誌. 2019. 128. 2. 69-78
平田真知佳, 宮裕昭, 足立晃平, 秋岡親司, 桑原康通. 歩行および登校が困難であった転換性障害患者に対する応用行動分析学的介入を行った一例. 市立福知山市民病院医学雑誌. 2016. 1. 62-67

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Education (2)：

2000 - 2004 Kyoto Prefectural University of Medicine Graduate School of Medical Science
1990 - 1996 Kyoto Prefectural University of Medicine

Professional career (1)：

博士(医学) (京都府立医科大学)

Work history (11)：

2022/07 - 現在 Kyoto Prefectural University of Medicine Department of Biochemistry and Molecular Biology Associate professor
2015/08 - 2022/06 Kyoto Prefectural University of Medicine
2013/04 - 2015/07 Kyoto Prefectural University of Medicine
2011/04 - 2013/03 Kyoto Prefectural University of Medicine
2010/11 - 2011/03 Kyoto Prefectural University of Medicine

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Committee career (2)：

『小児がん診療ガイドライン』2016 年版作成委員
小児血液がん学会評議員

Awards (2)：

2024/03 - 日本子ども健康科学会学術大会優秀発表賞
2005 - 京都府立医科大学学友会第15回京都府立医科大学学友会青蓮賞

Association Membership(s) (15)：

日本場面緘黙研究会 , 日本行動医学会 , 強度行動障害医療学会 , 日本子ども健康科学会 , THE JAPANESE ASSOCIATION FOR BEHAVIOR ANALYSIS , THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE BIOCHEMICAL SOCIETY , JAPANESE SOCIETY OF PEDIATRIC PSYCHIATRY AND NEUROLOGY , THE JAPANESE SOCIETY OF HEMATOLOGY , 日本エピジェネティクス研究会 , AMERICAN ASSOCIATION FOR CANCER RESEARCH , JAPAN SOCIETY OF CLINICAL ONCOLOGY , THE JAPANESE CANCER ASSOCIATION , THE JAPANESE SOCIETY OF PEDIATRIC HEMATOLOGY/ONCOLOGY , JAPAN PEDIATRIC SOCIETY

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