Kato Hiroaki

カトウヒロアキ | Kato Hiroaki

Affiliation and department：

Research field (4)： Molecular biology , Applied molecular and cellular biology , Systems genomics , Genomics

Research keywords (9)： RNAi , 熱ショックタンパク質 , R/Bioconductor , ヘテロクロマチン , 分裂酵母 , ヌクレオソーム , バイオインフォマティクス , chromatin , epigenetics

Research theme for competitive and other funds (13)：

2021 - 2024 Development of a translational correction method for resolutional improvement of nucleosome maps
2021 - 2023 High-resolution mapping of transcription-related non-canonical nucleosomes
2019 - 2021 Elucidation of the roles of nucleosomal DNA sequences in chromatin potential
2018 - 2021 ヌクレオソーム動的制御における内部塩基配列の役割の解明
2014 - 2017 Nucleosome formation and chromatin dynamics in microsatellite DNA sequences

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Papers (26)：

Kei Kawakami, Shin-ichi Maeda, Yoshiko Tanimoto, Mitsuhiro Shimizu, Hiroaki Kato. Budding Yeast Cap Analysis of Gene Expression Dataset of Two Cell Types. Genes & Genetic Systems. 2024
Hiroaki Kato, Mitsuhiro Shimizu, Takeshi Urano. Asymmetric patterns of nucleosome positioning sequences in protein-coding regions. 2023
Tomoko Sugiura, Hiroaki Sugiura, Hiroaki Kato, Yuko Nariai, Yuuki Mizumoto, Kozue Hanada, Rieko Takahashi, Yukari Hinotubo, Naoko Tanaka, Mutsumi Sasaki, et al. Kinetics of Anti-SARS-CoV-2 Antibody Response Following Two Doses of the BNT162b2 mRNA Vaccine: A Japanese Single-Center Primary Care Clinic Report Involving Volunteers and Patients with Autoimmune Disease. Infectious Disease Reports. 2022. 15. 1. 24-33
Koji Katsumata, Yuichi Ichikawa, Tomohiro Fuse, Hitoshi Kurumizaka, Akio Yanagida, Takeshi Urano, Hiroaki Kato, Mitsuhiro Shimizu. Sequence-dependent nucleosome formation in trinucleotide repeats evaluated by in vivo chemical mapping. Biochemical and Biophysical Research Communications. 2021. 556. 179-184
Hiroaki Kato, Mitsuhiro Shimizu, Takeshi Urano. Chemical map-based prediction of nucleosome positioning using the Bioconductor package nuCpos. BMC Bioinformatics. 2021. 22. 1. 322

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MISC (14)：

清水光弘, 加藤太陽. ヌクレオソームポジショニングのゲノムワイド解析. 細胞. 2020. 52. 503-507
加藤太陽, 浦野健. 熱ショックタンパク質はヘテロクロマチン形成に寄与する. 島根医学. 2018. 38. 3. 1-7
Takuya Kajitani, Hiroaki Kato, Yuji Chikashige, Hiroshi Kimura, Yasuyuki Ohkawa, Damien Herand, Yota Murakami. Phosphorylation at Ser7 of RNA polymerase II CTD limits transcription speed and transcription elongation. GENES & GENETIC SYSTEMS. 2016. 91. 6. 348-348
Takuya Kajitani, Hiroaki Kato, Yuji Chikashige, Yasushi Hiraoka, Hiroshi Kimura, Yasuyuki Ohkawa, Koji Nagao, Chikashis Obuse, Damien Hermand, Yota Murakavii. Ser7 phosphorylation of RNAPII-CTD ensures on-chromatin retention of nascent ncRNAs, facilitating establishment and epigenetic inheritance of RNAi-depnendent heterochromatin formation. GENES & GENETIC SYSTEMS. 2015. 90. 6. 360-360
Takuya Kajitani, Hiroaki Kato, Yuji Chikashige, Yasushi Hiraoka, Hiroshi Kimura, Yasuyuki Ohkawa, Damien Hermand, Yota Murakami. Phosphorylation at Ser7 of RNAPII-CTD ensures on-chromatin retention of nascent ncRNAs, triggering RNAi-dependent heterochromatin formation. GENES & GENETIC SYSTEMS. 2014. 89. 6. 331-331

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Patents (1)：

Books (1)：

DNA and Histone Methylation as Cancer Targets
Humana Press, Springer International Publishing AG 2017 ISBN:9783319597867

Lectures and oral presentations (5)：

Training a dHMM with a chemical map improved accuracy of nucleosome positioning prediction in yeasts
(Cold Spring Harbor Laboratory Meeting on Epigenetics & Chromatin 2018)
Relationship between base composition and occupancy of nucleosomes in transcribed, non-coding regions
(NCU Global Young Investigator Forum 2018 on "Regulatory Mechanisms of Epigenetic Information and Their Clinical and Applications" 2018)
細胞内のヌクレオソーム配置:予測と実測の比較から見えてきたこと
(日本農芸化学会中四国支部第26回若手研究者シンポジウム「農芸化学の新潮流を探る」 2017)
酵母から学ぶ遺伝子発現制御システム DNA配列から眺めた酵母のエピジェネティクス
(日本生化学会大会プログラム・講演要旨集 2016)
Spt6 prevents transcription-coupled loss of posttranslationally modified histone H3
(Message from Yeast to Epigenetics 2013)

Works (2)：

CRAN package AntibodyTiters
Yuuki Mizumoto, Hiroaki Kato, Takeshi Urano 2021 - 現在
Bioconductor package nuCpos
Hiroaki Kato, Takeshi Urano 2018 -

Education (4)：

Professional career (1)：

Work history (4)：

Committee career (1)：

Awards (3)：

2022/12 - 大隅基礎科学創成財団酵母コンソーシアムフェロー
2021/11 - The Genetics Society of Japan Best Papers Award 2021 Prediction of nucleosome positioning with a chemical hybrid model
2014 - 島根大学若手研究者優秀論文賞医科学研究における独創的で優れた論文

Association Membership(s) (3)：

THE MOLECULAR BIOLOGY SOCIETY OF JAPAN , THE JAPANESE SOCIETY FOR EPIGENETICS , THE GENETICS SOCIETY OF JAPAN

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