HIKITA TOMOYA

ヒキタトモヤ | HIKITA TOMOYA

Affiliation and department：
Homepage URL (1)： https://w3pharm.u-shizuoka-ken.ac.jp/radiobio/index.html

Research field (3)： Pharmaceuticals - health and biochemistry , Cell biology , Tumor biology

Research theme for competitive and other funds (9)：

2022 - 2025 生体イメージングに基づいたがん細胞外小胞による脂肪分解機構の解析
2022 - 2024 持続的な培地回収システムを用いた高機能エクソソームの探索と薬物送達への応用
2019 - 2022 In vivo imaging system of cancer-derived exosome using a BRET reporter
2017 - 2019 Mycoplasma hyorhinis as an infectious tumor-promoting factor
2017 - 2018 マイコプラズマのがん感染性因子としての重要性の解明

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Papers (23)：

Ryosuke Hayasaka, Sho Tabata, Masako Hasebe, Satsuki Ikeda, Tomoya Hikita, Chitose Oneyama, Jun Yoshitake, Daisuke Onoshima, Kumiko Takahashi, Takahiro Shibata, et al. Metabolomics of small extracellular vesicles derived from isocitrate dehydrogenase 1-mutant HCT116 cells collected by semi-automated size exclusion chromatography. Frontiers in Molecular Biosciences. 2023. 9
Tomoya Hikita, Chitose Oneyama. Quantification and Imaging of Exosomes via Luciferase-Fused Exosome Marker Proteins: ExoLuc System. Bioluminescence. 2022. 281-290
Fumie Mitani, Jianyu Lin, Tatsuya Sakamoto, Ryo Uehara, Tomoya Hikita, Takuya Yoshida, Andi Setiawan, Masayoshi Arai, Chitose Oneyama. Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function. Scientific Reports. 2022. 12. 1
Tomoya Hikita, Ryo Uehara, Reina E. Itoh, Fumie Mitani, Mamiko Miyata, Takuya Yoshida, Rui Yamaguchi, Chitose Oneyama. MEK/ERK-mediated oncogenic signals promote secretion of extracellular vesicles by controlling lysosome function. Cancer Science. 2022. 113. 4. 1264-1276
Shin Morioka, Hiroki Nakanishi, Toshiyoshi Yamamoto, Junya Hasegawa, Emi Tokuda, Tomoya Hikita, Tomoko Sakihara, Yuuki Kugii, Chitose Oneyama, Masakazu Yamazaki, et al. A mass spectrometric method for in-depth profiling of phosphoinositide regioisomers and their disease-associated regulation. Nature Communications. 2022. 13. 1

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MISC (1)：

Yuuki Ishida, Chiaki Fuse, Tomoya Hikita, Kosuke Shimizu, Tomohiro Asai, Naoto Oku. Functional analysis of junctional adhesion molecule-C (JAM-C) in cancer metastasis. CLINICAL & EXPERIMENTAL METASTASIS. 2007. 24. 4. 255-255

Education (3)：

2006 - 2010 大阪大学大学院医学系研究科予防環境学専攻
2004 - 2006 University of Shizuoka Graduate School of Pharmaceutical Sciences
2000 - 2004 University of Shizuoka School of Pharmaceutical Sciences Division of Medicinal Science

Professional career (1)：

Work history (5)：

Awards (4)：

2017/08 - 第4回日本細胞外小胞学会優秀奨励賞 Src enhances exosome production via interaction with ESCRT-associated protein, ALIX
2013/05 - 第40回日本マイコプラズマ学会学術集会優秀発表賞卵巣癌におけるマイコプラズマ感染の関与
2013/01 - 大阪大学微生物病研究所業績発表会微研財団優秀研究奨励賞 Involvement of mycoplasma infection in ovarian cancer progression
2010/01 - 研究奨励賞 Purvalanol A, a CDK inhibitor, effectively suppresses Src-mediated transformation by inhibiting both CDKs and c-Src

Association Membership(s) (3)：

JAPANESE SOCIETY OF EXTRACELLULAR VESICLES , JAPAN SOCIETY FOR CELL BIOLOGY , THE JAPANESE CANCER ASSOCIATION

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