Komizu Yuji

コミズユウジ | Komizu Yuji

Affiliation and department：

Research field (1)： Biomedical engineering

Research theme for competitive and other funds (7)：

2022 - 2025 肝星細胞の三次元培養による脂肪肝炎治療薬の新規スクリーニング系の開発
2020 - 2023 シリカ繊維三次元培養担体によるがん細胞薬剤耐性の再現と新規スクリーニング系の構築
2019 - 2022 Inhibitory Effects of Hybrid Nanoparticles Targeting Cancer Stem Cells and Their Application to Cancer Therapy
2016 - 2019 Selective elimination of tumorigenic hepatic stem cells using hybrid liposomes for application of regenerative medicine
2014 - 2017 Studies on the evaluation method for chemical compound toxicity to human hepatocytes by using hollow fiber type three dimensional culture module

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Papers (48)：

Shinichiro Horiuchi, Yukie Kuroda, Ryota Oyafuso, Yuji Komizu, Kazuya Maeda, Seiichi Ishida. Formation of functional, extended bile canaliculi, and increased bile acid production in sandwich-cultured human cryopreserved hepatocytes using commercially available culture medium. Archives of Toxicology. 2024. 98. 8. 2605-2617
Riko Jinno, Moe Tanaka, Yuji Komizu, Yoko Matsumoto, Taku Matsushita, Seiichi Ishida. Selective elimination of tumorigenic cells from mixed culture of normal and tumorigenic cells using hybrid liposomes aimed at realizing of cell therapy. Cytotechnology. 2024. 76. 2. 247-258
Shinichiro Horiuchi, Yukie Kuroda, Yuji Komizu, Seiichi Ishida. Consideration of Commercially Available Hepatocytes as Cell Sources for Liver-Microphysiological Systems by Comparing Liver Characteristics. Pharmaceutics. 2022. 15. 1. 55-55
Shinichiro Horiuchi, Yukie Kuroda, Ryota Oyafuso, Yuji Komizu, Takashi Takaki, Kazuya Maeda, Seiichi Ishida. Construction of a culture protocol for functional bile canaliculi formation to apply human iPS cell-derived hepatocytes for cholestasis evaluation. Scientific reports. 2022. 12. 1. 15192-15192
Riko Jinno, Yuji Komizu, Yurina Kado, Hideaki Ichihara, Yoko Matsumoto, Seiichi Ishida, Taku Matsushita. Evaluation for Inhibitory Effects of Hybrid Liposomes on the Growth of Breast Cancer Stem Cells using Soft Agar Colony Formation Assay. Alternatives to Animal Testing and Experimentation. 2021. 26. 1. 1-8

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MISC (16)：

親富祖亮太, 坂田望, 古水雄志, 岩佐卓哉, 佐々木皓平, 小島理恵, 川部雅章, 石田誠一, 石田誠一, 松下琢. 3次元培養担体Cellbedを用いた肝細胞の胆汁排泄機能の再構築に関する研究. 日本再生医療学会総会(Web). 2021. 20th
前田光平, 久保拓海, 堀内新一郎, 藤居瑠彌, 黒田幸恵, 古水雄志, 松下琢, 石田誠一, 石田誠一. 肝小葉zonationのMicrophysiological Systemsを用いた再構築に向けた検討. 日本再生医療学会総会(Web). 2021. 20th
角祐里奈, 陳野莉子, 古水雄志, 松本陽子, 松下琢, 石田誠一, 石田誠一. ハイブリッドリポソームの乳がん幹細胞に対する増殖抑制効果. 日本再生医療学会総会(Web). 2021. 20th
前田光平, 陳野莉子, 星野美宙, 井野川人姿, 古水雄志, 友重竜一, 松下琢. ハイドロキシアパタイト培養担体を用いた骨芽細胞様細胞の細胞増殖及び分化誘導に関する研究. 日本再生医療学会総会(Web). 2020. 19th
柄本和実, 井野川人姿, 古水雄志, 友重竜一, 松下琢. ハイドロキシアパタイト担体上におけるヒト骨芽細胞の分化誘導に関する研究. 日本再生医療学会総会(Web). 2019. 18th

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Professional career (1)：

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