Rchr
J-GLOBAL ID:201801001655972913   Update date: Sep. 12, 2020

Yanagiya Akiko

ヤナギヤ アキコ | Yanagiya Akiko
Affiliation and department:
Job title: 研究員
Research field  (4): Cell biology ,  Molecular biology ,  Animals: biochemistry, physiology, behavioral science ,  Laboratory animal science
Research keywords  (4): Spermatogenesis ,  Insulin biosynthesis ,  Translational control ,  Post-transcriptional regulation
Research theme for competitive and other funds  (3):
  • 2020 - 2022 膵β細胞の恒常性維持に重要なオートファジーの転写後制御の解析
  • 2018 - 2021 Analysis of the post-transcriptional regulation in glucose-induced insulin biosynthesis in pancreatic beta cells.
  • 2004 - 2006 Analysis of translational control in viral pathogenesis caused by RNA viruses
Papers (29):
  • Dina Mostafa, Akiko Yanagiya, Eleni Georgiadou, Yibo Wu, Theodoros Stylianides, Guy A. Rutter, Toru Suzuki, Tadashi Yamamoto. Loss of β-cell identity and diabetic phenotype in mice caused by disruption of CNOT3-dependent mRNA deadenylation. Communications Biology. 2020. 3. 1
  • Akinori Takahashi, Toru Suzuki, Shou Soeda, Shohei Takaoka, Shungo Kobori, Tomokazu Yamaguchi, Haytham Mohamed Aly Mohamed, Akiko Yanagiya, Takaya Abe, Mayo Shigeta, et al. The CCR4-NOT complex maintains liver homeostasis through mRNA deadenylation. Life Science Alliance. 2020. 3. 5
  • Mostafa, D., Takahashi, A., Yanagiya, A., Yamaguchi, T., Abe, T., Kureha, T., Kuba, K., Kanegae, Y., Furuta, Y., Yamamoto, T., et al. Essential functions of the CNOT7/8 catalytic subunits of the CCR4-NOT complex in mRNA regulation and cell viability. RNA Biology. 2020. 17. 3
  • Zakaria, C., Sean, P., Hoang, H.-D., Leroux, L.-P., Watson, M., Workenhe, S.T., Hearnden, J., Pearl, D., Truong, V.T., Robichaud, N., et al. Active-site mTOR inhibitors augment HSV1-dICP0 infection in cancer cells via dysregulated eIF4E/4E-BP axis. PLoS Pathogens. 2018. 14. 8
  • Bhat, M., Yanagiya, A., Graber, T., Razumilava, N., Bronk, S., Zammit, D., Zhao, Y., Zakaria, C., Metrakos, P., Pollak, M., et al. Metformin requires 4E-BPs to induce apoptosis and repress translation of Mcl-1 in hepatocellular carcinoma cells. Oncotarget. 2017. 8. 31. 50542-50556
more...
MISC (8):
  • Sooncheol Lee, Syed I. A. Bukhari, Samuel S. Truesdell, Swapna Kollu, Anthony Classon, Myriam Boukhali, Esha Jain, David Sweetser, Richard D. Mortensen, Akiko Yanagiya, et al. A specialized translation program in quiescent cancer cells. CLINICAL CANCER RESEARCH. 2017. 23. 24. 30-30
  • Shobha Vasudevan, Syed Irfan Ahmed Bukhari, Samuel Spencer Truesdell, Sooncheol Lee, Swapna Kollu, Anthony Classon, Myriam Boukhali, Esha Jain, Akiko Yanagiya, Ruslan Sadyrev, et al. A Specialized Mechanism of MicroRNA-mediated Translation in Quiescence. FASEB JOURNAL. 2016. 30
  • Shobha Vasudevan, Syed Irfan Ahmed Bukhari, Samuel Spencer Truesdell, Sooncheol Lee, Swapna Kollu, Anthony Classon, Myriam Boukhali, Esha Jain, Akiko Yanagiya, Ruslan Sadyrev, et al. A Specialized Mechanism of MicroRNA-mediated Translation in Quiescence. FASEB JOURNAL. 2016. 30
  • Peter S. Vosler, Yanqin Gao, Christopher S. Brennan, Akiko Yanagiya, Yu Gan, Guodong Cao, Feng Zhang, Simon J. Morley, Nahum Sonenberg, Michael V. L. Bennett, et al. NEUROSCIENCE (vol 108, pg 18102, 2011). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2013. 110. 49. 19968-19968
  • Peter S. Vosler, Yanqin Gao, Christopher S. Brennan, Akiko Yanagiya, Yu Gan, Guodong Cao, Feng Zhang, Simon J. Morley, Nahum Sonenberg, Michael V. L. Bennett, et al. Ischemia-induced calpain activation causes eukaryotic (translation) initiation factor 4G1 (eIF4GI) degradation, protein synthesis inhibition, and neuronal death (vol 108, pg 18102, 2011). PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. 2012. 109. 10. 4021-4021
more...
Lectures and oral presentations  (26):
  • Post-transcriptional regulation in insulin biosynthesis by the Ccr4-Not deadenylase complex in mouse pancreatic islets.
    (The 20th Annual Meeting of The RNA Society of Japan 2018)
  • Post-transcriptional regulation in glucose-stimulated insulin biosynthesis by the Ccr4-Not deadenylase complex in mouse pancreatic islets.
    (The 23rd Annual Meeting of the RNA Society 2018)
  • Post-transcriptional regulation via the mRNA poly(A) tail during spermatogenesis.
    (The 40th Annual Meeting of the Molecular Biology Society of Japan, ConBio2017 2017)
  • Translational control in spermatogenesis by poly(A)-binding protein-interacting protein 1.
    (The 19th Annual Meeting of The RNA Society of Japan. Toyama, Toyama, Japan 2017)
  • The physiological role of poly(A)-binding protein-interacting protein 1 in male germ cell development and memory formation.
    (Invited lecture at The Okinawa Institute of Science and Technology Graduate University 2016)
more...
Professional career (1):
  • 博士(薬学) (東京大学)
Work history (5):
  • 2017/04 - 現在 The Okinawa Institute of Science and Technology Graduate University Cell Signal unit Staff Scientist
  • 2008/04 - 2017/04 McGill University Department of Biochemistry Research Associate
  • 2003/06 - 2008/03 McGill University Department of Biochemistry Postdoctoral researcher
  • 2004/04 - 2006/03 McGill University Department of Biochemistry JSPS Overseas Research Fellow
  • 2003/04 - 2003/06 The University of Tokyo Graduate School of Medicine and Faculty of Medicine Researcher
Awards (1):
  • 2011/03 - McGill University McGill MedStar Award
Association Membership(s) (3):
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN ,  RNA Society ,  THE RNA SOCIETY OF JAPAN
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