Rchr
J-GLOBAL ID：201801001873685039
Update date: Jun. 08, 2023
Okashita Naoki
オカシタ ナオキ | Okashita Naoki
Affiliation and department：
Job title：
助教
Homepage URL (1)：
https://tachibana-lab.net/
Research field (1)：
Molecular biology
Research keywords (2)：
エピジェネティクス
, 性決定
Research theme for competitive and other funds (4)：
- 2020 - 2023 体外培養条件による性決定エピゲノム変異克服への挑戦
- 2018 - 2020 体外受精が胎児の性決定に及ぼす影響
- 2016 - 2018 ほ乳類の性決定に関わる新規エピゲノム制御因子の同定
- 2015 - 2016 多能性獲得・維持におけるRNAメチル化によるncRNAの安定化及び生成制御の役割
Papers (12)：
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Naoki Okashita, Ryo Maeda, Makoto Tachibana. CDYL reinforces male gonadal sex determination through epigenetically repressing Wnt4 transcription in mice. Proceedings of the National Academy of Sciences of the United States of America. 2023. 120. 20. e2221499120
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Naoki Okashita, Makoto Tachibana. Transcriptional Regulation of the Y-Linked Mammalian Testis-Determining Gene SRY. Sexual Development. 2021. 1-9
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Shingo Miyawaki, Shunsuke Kuroki, Ryo Maeda, Naoki Okashita, Peter Koopman, Makoto Tachibana. The mouse Sry locus harbors a cryptic exon that is essential for male sex determination. Science (New York, N.Y.). 2020. 370. 6512. 121-124
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Maiko Yamamoto, Yoshiaki Suwa, Kohta Sugiyama, Naoki Okashita, Masanori Kawaguchi, Naoki Tani, Kazumi Matsubara, Akira Nakamura, Yoshiyuki Seki. PRDM14-CtBP1/2-PRC2 complex regulates transcriptional repression during transition from primed to naïve pluripotency. Journal of Cell Science. 2020. jcs.240176-jcs.240176
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Naoki Okashita, Shunsuke Kuroki, Ryo Maeda, Makoto Tachibana. TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression. Scientific reports. 2019. 9. 1. 13462-13462
ｍore...
MISC (2)：
Lectures and oral presentations (1)：
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Elucidation of novel epigenetic regulatory machanism of the sex-determining gene “Sry”
(KEY Forum 2018 2018)
Education (3)：
- 2012 - 2015 Kwansei Gakuin University
- 2010 - 2012 Kwansei Gakuin University
- 2006 - 2010 Kwansei Gakuin University School of Science and Technology Department of Bioscience
Professional career (1)：
Work history (2)：
- 2019/04 - 現在 Osaka University Graduate School of Frontier Biosciences
- 2015/04 - 2019/03 The University of Tokushima
Association Membership(s) (2)：
THE MOLECULAR BIOLOGY SOCIETY OF JAPAN
, 日本エピジェネティクス研究会
