Honda Kotaro

ホンダコウタロウ | Honda Kotaro

Affiliation and department：

Research field (3)： Animals: biochemistry, physiology, behavioral science , Developmental biology , Pathobiochemistry

Research keywords (7)：行動 , Electrophysiology , かゆみ , 掻痒 , tissue engineering , taste , itch

Research theme for competitive and other funds (6)：

2022 - 2027 Development of oral antipruritic drugs by elucidating the spinal alloknesis circuitry
2020 - 2025 Elucidation of control mechanisms of itch targeting mu opioid receptors distributed in skin and development of novel antipruritic drugs
2022 - 2024 掻破行動を司る止痒成功確率に関する法則の解明
2020 - 2021 痒み-掻破ループ志向性の行動学的究明
2018 - 2021 Elucidation of the mechanisms of alloknesis (itch hypersensitivity) and development of treatment

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Papers (14)：

Go Kojima, Eriko Komiya, Kotaro Honda, Takahide Kaneko, Yasushi Suga, Mitsutoshi Tominaga, Kenji Takamori. Model of Chronic Itch in Aged Mice: Beneficial Effects of Drugs Affecting Descending Modulatory Systems. Acta Dermato-Venereologica. 2024. 104. adv39950-adv39950
Qiaofeng Zhao, Mitsutoshi Tominaga, Sumika Toyama, Eriko Komiya, Tomohiro Tobita, Motoki Morita, Ying Zuo, Kotaro Honda, Yayoi Kamata, Kenji Takamori. Effects of Psychological Stress on Spontaneous Itch and Mechanical Alloknesis of Atopic Dermatitis. Acta dermato-venereologica. 2024. 104. adv18685
Kotaro Honda, Mitsutoshi Tominaga, Fumiya Kusube, Kenji Takamori. Potential antipruritic neuronal targets of nalfurafine in the murine spinal dorsal horn. Itch. 2023. 8. e66
Eriko Komiya, Mitsutoshi Tominaga, Ryo Hatano, Yuji Kamikubo, Sumika Toyama, Hakushun Sakairi, Kotaro Honda, Takumi Itoh, Yayoi Kamata, Munehiro Tsurumachi, et al. Peripheral endomorphins drive mechanical alloknesis under the enzymatic control of CD26/DPPIV. Journal of Allergy and Clinical Immunology. 2021. 149. 3. 1085-1096
Yayoi Kamata, Mitsutoshi Tominaga, Yoshie Umehara, Kotaro Honda, Atsuko Kamo, Catharina Sagita Moniaga, Eriko Komiya, Sumika Toyama, Yasushi Suga, Hideoki Ogawa, et al. Calcium-inducible MAPK/AP-1 signaling drives semaphorin 3A expression in normal human epidermal keratinocytes. The Journal of investigative dermatology. 2020. 140. 7. 1346-1354

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MISC (19)：

Kotaro Honda, Mitsutoshi Tominaga, Kenji Takamori. New insight to understand the itch sensation as numerical data in mice. JOURNAL OF INVESTIGATIVE DERMATOLOGY. 2023. 143. 5S, Supplement 1. S234-S234
Kotaro Honda, Mitsutoshi Tominaga, Kenji Takamori. How to describe the quality of itching with objective probability of success. 2023
Honda Kotaro. New methodology to evaluate itch levels in mice. 2021. 183-183
古宮栄利子, 冨永光俊, 冨永光俊, 波多野良, 外山扇雅, 伊藤匠, 鎌田弥生, 鎌田弥生, 本田耕太郎, 大沼圭, et al. CD26/dipeptidyl-peptidase IVは機械的かゆみの調節因子である. 日本病態プロテアーゼ学会学術集会プログラム抄録集. 2021. 26th
Kotaro Honda, Mitsutoshi Tominaga, Fumiya Kusube, Fumiyuki Yamakura, Hisashi Naito, Kenji Takamori. Investigation of the antipruritic mechanism of the kappa opioid receptor agonist in the murine spinal dorsal horn. The Journal of Physiological Sciences. 2020. 70. supplement1. S125-S125

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Lectures and oral presentations (8)：

A problem of individual differences of behavioral data for itch-induced scratching bouts in mice
(The 101st Annual Meeting of The Physiological Society of Japan 2024)
Random repeat length of scratching bouts derived from Bernoulli trials
(12th World Congress on Itch 2023)
New insight to understand the itch sensation as numerical data in mice
(1st International Societies for Investigative Dermatology Meeting 2023)
How to describe the quality of itching with objective probability of success
(The 100th Anniversary Annual Meeting of The Physiological Society of Japan 2023)
Estimation of severity of itch from success probability of itch-extinguishing in mice
(The 47th Annual Meeting of the Japanese Society for Investigative Dermatology 2022)

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Education (2)：

2010 - 2016 Tokyo University of Science Graduate school of Industrial Science and Technology Department of Biological Science and Technology
2004 - 2010 Tokyo University of Science Faculty of Industrial Science and Technology Department of Biological Science and Technology

Professional career (1)：

Work history (3)：

2022/04 - 現在順天堂大学大学院医学研究科環境医学研究所非常勤助教
2017/04 - 2022/03 Juntendo University Institute for Environmental and Gender-Specific Medicine Postdoctoral Fellow
2016/12 - 2017/03 Tokyo University of Science Graduate School of Industrial Science and Technology Research Assistant

Awards (1)：

2017/01 - The society for in vitro biology JOURNAL HIGHLIGHT Nerve-independent and ectopically additional induction of taste buds in organ culture of fetal tongues

Association Membership(s) (3)：

THE JAPANESE ASSOCIATION FOR THE STUDY OF TASTE AND SMELL , THE JAPANESE SOCIETY FOR INVESTIGATIVE DERMATOLOGY , THE PHYSIOLOGICAL SOCIETY OF JAPAN

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