Yoshiyuki Manabe

マナベヨシユキ | Yoshiyuki Manabe

Affiliation and department：
Job title： Assistant Professor

Research field (1)： Bioorganic chemistry

Research keywords (3)：ケミカルバイオロジー , グリコシル化 , 糖鎖

Research theme for competitive and other funds (18)：

2020 - 2025 Elucidation of glycan function by synthetic glycans and glycan remodeling systems and their application to new immunotherapies
2021 - 2024 糖鎖・糖鎖修飾膜タンパク質を「つくる」ことによるタンパク質膜動態の可視化
2021 - 2024 Regulation of membrane dynamics by glycan chemical knock-in
2020 - 2023 シアリル糖鎖による免疫調節の分子基盤解明を目指したボトムアップアプローチ
2020 - 2022 Analysis and control of glycan function on cell surface crowding biosytems by synthetic biology

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Papers (97)：

Yoshiyuki Manabe, Brandon Gárate-Reyes, Keita Ito, Ramón Hurtado-Guerrero, Kazuya Kabayama, Koichi Fukase. Synthesis and immunological evaluation of TLR1/2 ligand-conjugated RBDs as self-adjuvanting vaccine candidates against SARS-CoV-2. Chemical communications (Cambridge, England). 2024
Kumpei Yano, Takuya Yoshimoto, Yoshiyuki Manabe, Koichi Fukase, Masato Tsutsui. Validation and Application of an Innovative Protective Group Concept: Enhancing Substrate Reactivity in Glycosylations by Disrupting Intermolecular Interactions. Synlett. 2024
Al Arofatus Naini, Tri Mayanti, Rani Maharani, Desi Harneti, Nurlelasari, Kindi Farabi, Sofa Fajriah, Erina Hilmayanti, Kazuya Kabayama, Atsushi Shimoyama, et al. Paraxylines A-G: Highly oxygenated preurianin-type limonoids with immunomodulatory TLR4 and cytotoxic activities from the stem bark of Dysoxylum parasiticum. Phytochemistry. 2024. 114009-114009
Koichi Fukase, Yoshiyuki Manabe, Atsushi Shimoyama. Diacetyl strategy for synthesis of NHAc containing glycans: enhancing glycosylation reactivity via diacetyl imide protection. Frontiers in Chemistry. 2023. 11
Keita Ito, Hiroto Furukawa, Hiroshi Inaba, Shino Ohshima, Yoshie Kametani, Masatoshi Maeki, Manabu Tokeshi, Xuhao Huang, Kazuya Kabayama, Yoshiyuki Manabe, et al. Antigen/Adjuvant-Displaying Enveloped Viral Replica as a Self-Adjuvanting Anti-Breast-Cancer Vaccine Candidate. Journal of the American Chemical Society. 2023. 145. 29. 15838-15847

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MISC (46)：

伊藤啓太, 古川寛人, 真鍋良幸, 大島志乃, 亀谷美恵, 樺山一哉, 稲葉央, 松浦和則, 深瀬浩一. Tumor-antigen-displayed Enveloped Viral Replica (2): Immunological Evaluation. 日本化学会春季年会講演予稿集(Web). 2023. 103rd
三浦彩音, 樺山一哉, 樺山一哉, 真鍋良幸, 真鍋良幸, 三宅秀斗, 白川明日香, 初村洋紀, 山地俊之, 鈴木健一, et al. Observation of Membrane Molecular Dynamics in Glycan Chemical Knockin Cells. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
飯塚結貴, 樺山一哉, 樺山一哉, 樺山一哉, 真鍋良幸, 真鍋良幸, 真鍋良幸, 深瀬浩一, 深瀬浩一, 深瀬浩一. Development of Antibody-drug Conjugate for Nuclear-selective Drug Delivery. 日本分子生物学会年会プログラム・要旨集(Web). 2022. 45th
伊藤啓太, 真鍋良幸, 真鍋良幸, 大島志乃, 亀谷美恵, 真栄城正寿, 渡慶次学, 樺山一哉, 樺山一哉, 深瀬浩一, et al. 抗原-自然免疫リガンド共集積化リポソームワクチンの調製と機能評価. 日本ワクチン学会学術集会プログラム・抄録集. 2022. 26th
平尾宏太郎, 真鍋良幸, 真鍋良幸, 樺山一哉, 樺山一哉, 深瀬浩一, 深瀬浩一. Synthesis of fluorescent labeled dolichol-phosphate mannose for analyzing post-translational mannosylation mechanism. 日本化学会春季年会講演予稿集(Web). 2022. 102nd

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Books (2)：

セルフアジュバンティングストラテジーによる合成ワクチン開発
技術情報協会 2017 ISBN:9784861046872
Glycochemical Synthesis: Strategies and Applications, Chapter8, Sugar Synthesis by microfluidic Techniques
Wiley 2016 ISBN:9781118299845

Education (3)：

Professional career (1)：

Work history (3)：

Awards (2)：

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