Rchr
J-GLOBAL ID:201801002171353204   Update date: Jul. 01, 2022

Ikeda Yoshiki

イケダ ヨシキ | Ikeda Yoshiki
Affiliation and department:
Research field  (1): Pharmaceuticals - chemistry and drug development
Research theme for competitive and other funds  (6):
  • 2021 - 2026 Development of next-generation-antibodies based on shark VNAR platform
  • 2022 - 2024 Novel GBM therapeutic drug development targeting on Integrin
  • 2020 - 2023 Talin1によるインテグリン活性化を介した神経膠(芽)腫悪性化メカニズムの解明
  • 2021 - 2022 未利用水産資源を有効活用する次世代抗体作製技術のフィー ジビリティスタディ
  • 2020 - 2022 Discovery and Development of Drugs for Glioblastoma based on Integrin inhibition
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Papers (15):
  • Koh Takeuchi, Yoshiki Ikeda, Miki Senda, Ayaka Harada, Koji Okuwaki, Kaori Fukuzawa, So Nakagawa, Hong Yang Yu, Lisa Nagase, Misaki Imai, et al. The GTP responsiveness of PI5P4Kβ evolved from a compromised trade-off between activity and specificity. Structure (London, England : 1993). 2022. 30. 6. 886-899
  • Yoshiki Ikeda, Akiyoshi Hirayama, Satoshi Kofuji, Yoshihisa Hirota, Ryo Kamata, Natsuki Osaka, Yuki Fujii, Mika Sasaki, Satsuki Ikeda, Eric P Smith, et al. SI-MOIRAI: A new method to identify and quantify the metabolic fate of nucleotides. The Journal of Biochemistry. 2021
  • Natsuki Osaka, Yoshihisa Hirota, Doshun Ito, Yoshiki Ikeda, Ryo Kamata, Yuki Fujii, Venkat R. Chirasani, Sharon L. Campbell, Koh Takeuchi, Toshiya Senda, et al. Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification. Frontiers in Molecular Biosciences. 2021. 8
  • Kentaro Kawai, Mami Tomonou, Yume Machida, Yukiko Karuo, Atsushi Tarui, Kazuyuki Sato, Yoshiki Ikeda, Tatsuo Kinashi, Masaaki Omote. Effect of Learning Dataset for Identification of Active Molecules: A Case Study of Integrin αIIbβ3 Inhibitors. Molecular informatics. 2021
  • Masanori A. Murayama, Nagisa Arimitsu, Jun Shimizu, Naruyoshi Fujiwara, Kenji Takai, Yoshiki Ikeda, Yoko Okada, Chieko Hirotsu, Erika Takada, Tomoko Suzuki, et al. Female dominance of both spatial cognitive dysfunction and neuropsychiatric symptoms in a mouse model of Alzheimer’s disease. Experimental Animals. 2021. 70. 3. 398-405
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MISC (5):
Patents (2):
  • Therapeutic drug for myasthenia gravis
  • Nitrogen-containing compounds, and markers for predicting tumor malignancy
Books (2):
  • 実験医学増刊 Vol.35 No.10 がん代謝 ワールブルグを超えて全容解明に挑む
    羊土社 2017
  • 大腸菌におけるRNase EとRNA結合タンパク質Hfq間の相互作用領域の解析
    名古屋大学 2011
Lectures and oral presentations  (10):
  • Toward establishment for in silico-oriented Science
    (2021)
  • インテグリン関連疾患治療薬開発に向けた薬剤スクリーニング法の開発
    (スクリーニング学研究会 2019)
  • アカデミア創薬・インテグリン創薬コンソーシアム事業から学ぶアカデミア創薬研究の流れ
    (スクリーニング学研究会 2019)
  • The physiological role of GTP sensing activity of PI5P4Kβ and its evolutional aspects
    (The Molecular Biology Society of Japan 2018 2018)
  • Structure-based screening to identify inhibitor against GTP-sensor kinase, PI5P4Kβ, for cancer therapy.
    (UC symposia conference 2018 2018)
more...
Professional career (1):
  • 理学 (名古屋大学)
Awards (1):
  • 2022/03 - Kansai Medical University Outstanding Researcher evaluates
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