Akihiro Sugai

スガイアキヒロ | Akihiro Sugai

Affiliation and department：

Research field (1)： Neurology

Research theme for competitive and other funds (4)：

2022 - 2025 脳小血管線維化促進細胞の同定による脳小血管老化の解明
2020 - 2023 選択的スプライシングの操作により天然変性領域を制御するALS治療戦略の検証
2017 - 2020 Therapeutic strategy for ALS with nucleic acid technology focusing on the vulnerability of TDP-43 autoregulation
2015 - 2017 Modeling ALS with TDP-43 proteinopathy

Papers (32)：

Akihiro Sugai, Takuma Yamagishi, Shingo Koide, Osamu Onodera. The Multifaceted Regulation of TDP-43 Condensates at the Intersection of Physiology and Pathology: Implications for Neurodegenerative Diseases. Phase Separation in Living Cells. 2023. 253-270
Yuka Koike, Akihiro Sugai, Norikazu Hara, Junko Ito, Akio Yokoseki, Tomohiko Ishihara, Takuma Yamagishi, Shintaro Tsuboguchi, Mari Tada, Takeshi Ikeuchi, et al. Age-related demethylation of the TDP-43 autoregulatory region in the human motor cortex. Communications Biology. 2021. 4. 1. 1107-1107
Taisuke Kato, Ri-Ichiroh Manabe, Hironaka Igarashi, Fuyuki Kametani, Sachiko Hirokawa, Yumi Sekine, Natsumi Fujita, Satoshi Saito, Yusuke Kawashima, Yuya Hatano, et al. Candesartan prevents arteriopathy progression in cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy model. The Journal of clinical investigation. 2021. 131. 22
小池佑佳, 須貝章弘, 原範和, 伊藤絢子, 横関明男, 石原智彦, 山岸拓磨, 坪口晋太朗, 他田真理, 池内健, et al. 加齢と関連したDNA脱メチル化がTDP-43量の自己調節機構を障害する. Dementia Japan. 2021. 35. 4. 610-610
Kosei Nakamura, Akihiro Sugai, Etsuji Saji, Kensaku Kasuga, Osamu Onodera. Refractory Myositis Affecting the Intrinsic Muscles of the Hand. Internal medicine (Tokyo, Japan). 2020. 59. 9. 1211-1214

ｍore...

MISC (30)：

ｍore...

Professional career (1)：

Work history (6)：

2023/04 - 現在新潟大学医歯学総合病院脳神経内科
2019/10 - 2023/03 Niigata University Brain Research Institute Center for Bioresources Brain Science Branch Department of Molecular Neuroscience
2019/04 - 2019/09 Niigata University Medical and Dental Hospital
2017/11 - 2019/03 Niigata University University Medical and Dental Hospital Advanced Disaster Medical and Emergency Critical Care Center Specially Appointed Assistant Professor
2016/06/01 - 2017/10/31 Niigata University University Medical and Dental Hospital Neurology Specially Appointed Assistant Professor

Show all

Awards (1)：

※ Researcher’s information displayed in J-GLOBAL is based on the information registered in researchmap. For details, see here.

Return to Previous Page