Rchr
J-GLOBAL ID:201801002340898142   Update date: Jun. 20, 2024

Nakamura Akira

ナカムラ アキラ | Nakamura Akira
Affiliation and department:
Research field  (3): Immunology ,  Experimental pathology ,  Respiratory medicine
Research keywords  (6): serine protease inhibitor ,  セリンプロテアーゼインヒビター ,  Fc receptor ,  Fc受容体 ,  immunoglobulin-like receptor ,  免疫グロブリン様受容体
Research theme for competitive and other funds  (20):
  • 2020 - 2023 セリンプロテアーゼインヒビターを標的とした好酸球性炎症の病態解明と治療法の開発
  • 2013 - 2019 セリンプロテアーゼインヒビター欠損細胞を用いた化学物質過敏症の高感度in vitro評価系の開発
  • 2014 - 2018 A DNA damage-independent role for 53BP1 in apoptotic cells
  • 2016 - 2018 免疫グロブリン様受容体によるウイルス誘導性脱随疾患モデルの発症機序の解明と制御
  • 2013 - 2015 セリンプロテアーゼインヒビターによるアレルギー反応の制御機構の解明
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Papers (56):
  • Atsuya Sawabe, Shogo Okazaki, Akira Nakamura, Ryo Goitsuka, Tomonori Kaifu. The orphan G protein-coupled receptor 141 expressed in myeloid cells functions as an inflammation suppressor. Journal of leukocyte biology. 2024
  • Kazuya Takeda, Tomonori Kaifu, Ryunosuke Michihata, Naotaka Kinugawa, Atushi Fujioka, Ayaka Tateno, Kaoru Toshima, Hirotaka Kanoh, Kei-Ichiro Inamori, Keiju Kamijo, et al. Chronic encephalomyelitis virus exhibits cellular tropism and evades pDCs by binding to sialylated integrins as the cell surface receptors. European Journal of Immunology. 2023
  • Tomonori Kaifu, Takumi Maruhashi, Soo-Hyun Chung, Kenji Shimizu, Akira Nakamura, Yoichiro Iwakura. DCIR suppresses osteoclastic proliferation and resorption by downregulating M-CSF and RANKL signaling. Frontiers in immunology. 2023. 14. 1159058-1159058
  • Yuki Kohada, Akito Kuromoto, Kazuya Takeda, Hiromichi Iwamura, Yuri Atobe, Jun Ito, Tomonori Kaifu, Yasuhiro Kaiho, Ichiro Nakashima, Nobuyuki Hinata, et al. Circulating PMN-MDSC level positively correlates with a poor prognosis in patients with metastatic hormone-sensitive prostate cancer. Frontiers in Urology. 2022. 2
  • Akito Morimoto, Junichi Kikuta, Keizo Nishikawa, Takao Sudo, Maki Uenaka, Masayuki Furuya, Tetsuo Hasegawa, Kunihiko Hashimoto, Hiroyuki Tsukazaki, Shigeto Seno, et al. SLPI is a critical mediator that controls PTH-induced bone formation. Nature Communications. 2021. 12. 1. 2136-2136
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MISC (92):
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Patents (5):
  • リウマチ関節炎好発モデル動物
  • 移植片対宿主病(GVHD)モデル動物
  • グッドパスチャー症候群モデルマウス
  • ギラン・バレー症候群及び/又はフィッ シャー症候群発症モデル非ヒト動物
  • 全身性エリテマトーデスモデル非ヒト動物
Books (4):
  • 標準免疫学
    医学書院 2013
  • 内科診断学
    医学書院 2010
  • Multichain Immune Recognition Receptor Signaling: From Spatiotemporal Organization to Human Disease
    Landes bioscience 2008
  • Activating and Inhibitory Immunoglobulin-Like Receptors
    Springer-Verlag Tokyo 2001
Lectures and oral presentations  (2):
  • TLR signals posttranscriptionally regulate the cytokine trafficking mediator sortilin
    (Gordon Research Conference on Protein Processing, Trafficking and Secretion 2016)
  • Development of high sensitivity in vitro assessment system of chemical- mediated hypersensitivity by using serine protease inhibitor-deficient cells
    (International Council of Chemical Associations' Long-Range Research Initiative Workshop 2016)
Education (2):
  • 1998 - 2001 Tohoku University Graduate School of Medicine
  • 1988 - 1994 Akita University School of Medicine
Professional career (1):
  • 博士(医学) (東北大学大学院医学研究科)
Work history (10):
  • 2016/04 - 現在 Tohoku Medical and Pharmaceutical University
  • 2010/09 - 2016/03 Kanazawa Medical University School of Medicine
  • 2007/10 - 2010/08 Tohoku University Institute of Development, Aging and Cancer
  • 2004/10 - 2007/09 Tohoku University Institute of Development, Aging and Cancer
  • 2002/04 - 2004/09 Tohoku University Institute of Development, Aging and Cancer
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Committee career (3):
  • 2018/04 - 現在 公私立大学実験動物施設協議会 代議員
  • 2010/04 - 現在 Journal of Biochemistry Editorial board
  • 1999/04 - 2009/03 日本生化学会 企画協力委員
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