2018 - 2021 Establishment of Identification of TCR antigen and prediction of side effects for TCR gene therapy
2018 - 2021 抗フラビウイルス薬の創製を目指した中和モノクローナル抗体認識の立体構造基盤
2018 - 2021 The induced RNA-binding protein, HuR targets of IL-6 mRNA and enhances its stabilization in periodontitis
2019 - 2021 Establishment of cancer immunotherapy using rabbit-derived humanized T cell receptor-like antibody
2017 - 2020 Development of Zika fever- and AIDS-peptide vaccine using next generation chip, T-ISAAC
2017 - 2020 New immune-Kampo therapy for breast cancer patients
2016 - 2019 Noncanonical activation of receptor tyrosine kinases: next target mechanisms for cancer progression
2017 - 2019 Development of an innovative isolation method for T cell receptor-like antibodies using lymphocyte chip for cancer therapy
2015 - 2018 Generation of individualized cancer immuno-therapy independent of HLA-haplotypes
2015 - 2018 Challenge to establish new preventive and therapeutic methods for rheumatoid arthritis
2016 - 2018 日本人のHLAに至適化したネオアンチゲンの迅速同定法の開発
2014 - 2017 Development of an innovative lymphocyte chip to establish personalized immuno-therapy for infectious diseases
2013 - 2016 Study of prognostic biomarker KLF4 and Her4 for triple negative breast cancer
2013 - 2016 Challenge the infectious diseases and cancers using innovative array technology: Development of hTEC10
2012 - 2014 Detection of cancer specific T cells on a chip
2011 - 2014 Establishment of personalized immunotherapy method for virus-infected diseases using lymphocyte chip
2011 - 2012 Development of rapid generation of antibodies with high affinity for improvement of detection limi
2009 - 2010 Isolation and characterization of a human monoclonal antibody against M2 of influenza A virus for reduction of avian influenza
2008 - 2010 A new strategy for antibody-therapy against infectious diseases and bacterial terrorism using lymphocyte-chip
2008 - 2010 Preparation of CCP antibodies library in Rheumatoid Arthritis and its clinical application
2008 - 2009 次世代マイクロチップを用いた単一リンパ球機能のハイスループット解析法の開発
2006 - 2007 リンパ球マイクロアレイを用いた免疫機能の診断・治療システムの開発
2006 - 2007 Development of rapid production of human monoclonal antibodies against emerging infectious pathogens using lymphocyte chip
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Papers (73)：
Kohdai Yamada, Fumiya Soga, Soh Tokunaga, Hikaru Nagaoka, Tatsuhiko Ozawa, Hiroyuki Kishi, Eizo Takashima, Tatsuya Sawasaki. GATS tag system is compatible with biotin labelling methods for protein analysis. Scientific Reports. 2023. 13. 1
Shohei Kikuchi, Akinori Wada, Yusuke Kamihara, Kosuke Okazaki, Paras Jawaid, Mati Ur Rehman, Eiji Kobayashi, Takeshi Susukida, Tomoki Minemura, Yoshimi Nabe, et al. DPP8 Selective Inhibitor Tominostat as a Novel and Broad-Spectrum Anticancer Agent against Hematological Malignancies. Cells. 2023. 12. 7
Tsukasa Osaki, Masayoshi Souri, Tatsuhiko Ozawa, Atsushi Muraguchi, Akitada Ichinose. Epitope analysis of human monoclonal antibodies from a patient with autoimmune factor XIII deficiency reveals their inhibitory mechanisms. FEBS Letters. 2023. 597. 9. 1275-1289
My Thi Viet Ha, Hiroshi Hamana, Kiyomi Shitaoka, Abdul Hayee, Eiji Kobayashi, Toshiaki Yoshikawa, Tetsuya Nakatsura, Reiko Saikawa, Eri Sato, Mitsujiro Osawa, et al. Selection of highly responsive T cell receptors by an analysis combining the expression of multiple markers. Cancer science. 2023
Kuang-Yu Chen, Jayaprakash Karuppusamy, Mary B. O’Neill, Vaitea Opuu, Mathieu Bahin, Sophie Foulon, Pablo Ibanez, Lluis Quintana-Murci, Tatsuhiko Ozawa, Sylvie van der Werf, et al. High-throughput droplet-based analysis of influenza A virus genetic reassortment by single-virus RNA sequencing. Proceedings of the National Academy of Sciences. 2023. 120. 6
